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Search Results for " LRR "

ターゲット

阻害剤

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T37011	Boc-LRR-AMC		Others
	Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is r...		Others
T8956	BC-1258	BC-1258	Apoptosis
	BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.		Apoptosis
T11878	LRRK2 inhibitor 1		LRRK2 , CDK
	LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.		LRRK2 , CDK
T2246	LRRK2-IN-1		Apoptosis , LRRK2 , CDK
	LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.		Apoptosis , LRRK2 , CDK
T73176	LRRK2-IN-7		Others
	LRRK2-IN-7 is a potent LRRK2 kinase inhibitor that demonstrates high selectivity and central nervous system (CNS) penetration, possessing an IC50 value of 0.9 nM. It exhibits more than 1000-fold selectivity against a bro...		Others
T82929	AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG
	The compound AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG facilitates bone ossification and has potential applications in the study of conditions associated with osteogenic insufficiency or diminished bone mineral densi...
T82170	HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2
	HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2 is a peptide with anti-inflammatory properties [1].
TMAZ-0308B	Anti-LRRC3 Monoclonal Antibody-Biotin

TMAZ-0076B	Anti-LRRN1 Monoclonal Antibody-Biotin

TMAZ-0308A5	Anti-LRRC3 Monoclonal Antibody-AF555

TMAZ-0308	Anti-LRRC3 Monoclonal Antibody

TMAZ-0076	Anti-LRRN1 Monoclonal Antibody

TMAZ-0076A5	Anti-LRRN1 Monoclonal Antibody-AF555

T72421	LRRK2/NUAK1/TYK2-IN-1		Others
	LRRK2/NUAK1/TYK2-IN-1 (compound 226) exhibits inhibitory activity against LRRK2 (Wt), LRRK2 (G2019), TYK2, and NUAK1, demonstrating IC50 values below 10 nM. This compound is useful for research into autoimmune diseases.		Others
T63620	LRRK2-IN-3		Others
	LRRK2-IN-3 is a potent, selective, orally active LRRK2 inhibitor that crosses the blood-brain barrier with an IC50 value of 0.6 nM in hPBMCs. LRRK2-IN-3 can be used to study Parkinson's disease.		Others
T83737	LRRKtide TFA	Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564)
	LRRKtide, a peptide substrate for leucine-rich repeat kinase 2 (LRRK2)—an enzyme often mutated in Parkinson's disease patients—corresponds to amino acids 550-564 of the membrane-organizing extension spike protein (moesin...
T80550	N-myristoyl-RKRTLRRL		PKC
	N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+)- and phosphatidylserine (PS)-dependent phosphorylation of histones, exhibiting an IC50 of 5 μM....		PKC
TMAZ-0076A6	Anti-LRRN1 Monoclonal Antibody-AF647

TMAZ-0076P	Anti-LRRN1 Monoclonal Antibody-PE

TMAZ-0308A6	Anti-LRRC3 Monoclonal Antibody-AF647

TMAZ-0076A	Anti-LRRN1 Monoclonal Antibody-APC

TMAZ-0076A4	Anti-LRRN1 Monoclonal Antibody-AF488

TMAZ-0308A4	Anti-LRRC3 Monoclonal Antibody-AF488

T63621	LRRK2-IN-4		Others
	LRRK2-IN-4 is a potent, selective, orally active, leucine-rich repeat kinase 2 (LRRK2) inhibitor that crosses the blood-brain barrier with an IC50 value of 2.6 nM. LRRK2-IN-3 has shown investigational potential in Parkin...		Others
T63824	LRRK2-IN-2		Others
	LRRK2-IN-2 is a selective, potent, and orally active LRRK2 inhibitor (IC50: 0.6 nM) that crosses the blood-brain barrier. LRRK2-IN-2 can be used to study Parkinson's disease.		Others
T79746	LRRK2-IN-10		LRRK2
	LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2 pS935 and 5.2 nM for G2019S-LRRK2 pS1292. It holds promise for...		LRRK2
TMAZ-0308P	Anti-LRRC3 Monoclonal Antibody-PE

TMAZ-0308A	Anti-LRRC3 Monoclonal Antibody-APC

T62871	LRRK2-IN-6		Others
	LRRK2-IN-6 (compound 22) is an orally active, selective leucine-rich repeat protein kinase 2 gene (LRRK2) inhibitor with blood-brain barrier permeability that inhibits GS LRRK2 (IC50: 4.6 μM) and WT LRRK2 (IC50: 49 μM). ...		Others
T63057	LRRK2-IN-5		Others
	LRRK2-IN-5 (compound 25) is an oral active, blood-brain barrier penetrating, selective leucine-rich repeat protein kinase 2 (LRRK2) inhibitor, which is effective for GS LRRK2 (IC50: 1.2 μM) and WT LRRK2 (IC50:16 μM) had ...		Others
T8553	BC-1471		Others
	BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT, LRR and PYD domains-containing protein 7) [1].		Others

Compounds

Target: Apoptosis, LRRK2, CDK

AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG

T82929

Synonym:

Target:

HSDAVFTDNYTRLRRQLAVRRYLNSILN-NH2

T82170

Synonym:

Target:

Anti-LRRC3 Monoclonal Antibody-Biotin

TMAZ-0308B

Synonym:

Target:

Anti-LRRN1 Monoclonal Antibody-Biotin

TMAZ-0076B

Synonym:

Target:

Anti-LRRC3 Monoclonal Antibody-AF555

TMAZ-0308A5

Synonym:

Target:

Anti-LRRC3 Monoclonal Antibody

TMAZ-0308

Synonym:

Target:

Anti-LRRN1 Monoclonal Antibody

TMAZ-0076

Synonym:

Target:

Anti-LRRN1 Monoclonal Antibody-AF555

TMAZ-0076A5

Synonym:

Target:

LRRK2/NUAK1/TYK2-IN-1

Synonym: Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564)

Anti-LRRN1 Monoclonal Antibody-AF647

TMAZ-0076A6

Synonym:

Target:

Anti-LRRN1 Monoclonal Antibody-PE

TMAZ-0076P

Synonym:

Target:

Anti-LRRC3 Monoclonal Antibody-AF647

TMAZ-0308A6

Synonym:

Target:

Anti-LRRN1 Monoclonal Antibody-APC

TMAZ-0076A

Synonym:

Target:

Anti-LRRN1 Monoclonal Antibody-AF488

TMAZ-0076A4

Synonym:

Target:

Anti-LRRC3 Monoclonal Antibody-AF488

Anti-LRRC3 Monoclonal Antibody-PE

TMAZ-0308P

Synonym:

Target:

Anti-LRRC3 Monoclonal Antibody-APC

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-05085	LRRC32 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRRC32 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7.
TMPJ-00338	LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u...
TMPJ-01222	LRRC25 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Leucine-rich repeat-containing protein 25(LRRC25) is a single-pass type I membrane protein and contains 3 LRR (leucine-rich) repeats. The protein expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendriti...
TMPY-02491	LRRN3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of the leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-...
TMPY-06910	LRRC15 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	LRRC15 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.28 kDa and the accession number is G7NYR2.
TMPY-04856	LRRTM2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LRRTM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is O43300.
TMPY-06148	LRRC15 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is Q8TF66-1.
TMPY-05375	LRRC32 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	LRRC32 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7.
TMPK-01380	LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPK-01070	LRRC15 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPY-01655	LRRTM4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRRTM4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q86VH4-1.
TMPY-06703	LRRC32 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LRRC32 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is G3XA59.
TMPY-00353	LRRC3B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5.
TMPY-06919	LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	LRRC15 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60.74 kDa and the accession number is NP_083249.1.
TMPY-00068	LRRTM4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LRRTM4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80XG9-2.
TMPK-00338	LRRC15 Protein, Human, Recombinant (His & Avi)	Human	CHO Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPJ-00364	LRRC32 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency a...
TMPY-05803	NGL-1/LRRC4C Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NGL-1/LRRC4C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.51 kDa and the accession number is Q9HCJ2.
TMPY-00088	LRRC3B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5.
TMPY-05437	NGL-1/LRRC4C Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	NGL-1/LRRC4C Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.5 kDa and the accession number is BAC27884.1.
TMPY-06705	LRRC32 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LRRC32 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.10 kDa and the accession number is G3XA59.
TMPY-04823	LRRTM2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LRRTM2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is O43300.
TMPK-01309	LRRC15 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPK-01030	LRRN1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction be...
TMPJ-00231	LRG1 Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transducti...
TMPJ-00320	AMIGO2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LR...
TMPY-02484	SLITRK4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family. This protein is characterized as an integral membrane protein that has two leucine-rich repeat (LRR) domains and a carboxy-terminal domai...
TMPY-03058	SLITL2/VASN Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular...
TMPY-03063	SLITRK6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domain...
TMPY-01438	FLRT3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Leucine-rich repeat transmembrane protein FLRT3, also known as Fibronectin-like domain-containing leucine-rich transmembrane protein 3, and FLRT3, is a single-pass type I membrane protein which belongs to the fibronectin...
TMPJ-00924	Decorin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPJ-00277	NgR3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family....
TMPY-02032	FLRT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1...