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天然化合物

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カタログ番号	製品名	別名	ターゲット
T78811	PROTAC AR-NTD degrader 1		Androgen Receptor
	PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal domain (AR-NTD) of the Androgen Receptor variant AR-V7. By antago...		Androgen Receptor
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
T28502	Ralaniten	EPI-002	Androgen Receptor
	Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites...		Androgen Receptor
T20000	I-XW-053		HIV Protease
	I-XW-053 is a capsid targeted HIV-1 replication inhibitor.		HIV Protease
T36375	Ralaniten triacetate	EPI-506	Androgen Receptor
	Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate...		Androgen Receptor
T35841	5-Benzyloxygramine		Dopamine Receptor , 5-HT Receptor
	5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...		Dopamine Receptor , 5-HT Receptor
T71527	NSC145366
	NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in alloster...
T75171	BacPROTAC-1
	BacPROTAC-1, a potent mSA BacPROTAC degrader, exhibits high affinity for both mSA and the N-terminal domain (NTD) of ClpC, with dissociation constants (K D) of 3.9 μM and 2.8 μM, respectively [1].
T75168	Homo-BacPROTAC7
	Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].
T75167	Homo-BacPROTAC6
	Homo-BacPROTAC6, a ClpC1 NTD BacPROTAC degrader, effectively targets ClpC2, while Homo-BacPROTAC7 has been shown to efficiently kill M. tuberculosis [1].
T78810	BWA-522		Androgen Receptor
	BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL) and the AR-V7 splice variant. It specifically antagonizes the...		Androgen Receptor

Compounds

PROTAC AR-NTD degrader 1

T78811

Synonym:

Target: Androgen Receptor

EPI-001

T6829

Synonym: EPI001,EPI 001

Target: Apoptosis, Androgen Receptor, PPAR

Ralaniten

T28502

Synonym: EPI-002

Target: Androgen Receptor

Target: Androgen Receptor

5-Benzyloxygramine

T35841

Synonym:

Target: Dopamine Receptor, 5-HT Receptor

Target: Androgen Receptor

カタログ番号	製品名	別名	ターゲット
T83582	(±)-Pantothenic acid	(±)-Vitamin B5,(±)-Pantothenate
	(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is essential for coenzyme A (CoA) biosynthesis in mammalian cells and exhibits protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD...

天然物製品

(±)-Pantothenic acid

T83582

Synonym: (±)-Vitamin B5,(±)-Pantothenate

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00444	SARS-COV-2 Spike S1 NTD Protein (His & Flag)	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPY-06114	SARS-CoV-2 Nucleocapsid NTD Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid NTD Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P0DTC9.
TMPY-06007	SARS-CoV-2 Spike S1 NTD Protein (His & Avi)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (His & Avi) is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.89 kDa and the accession number is A0A6G7K2L4.
TMPK-00267	SARS-COV-2 Nucleocapsid Protein NTD Domain (His & Avi), Biotinylated	SARS-CoV-2	E. coli
	Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i...
TMPK-00262	SARS-COV-2 Nucleocapsid Protein NTD Domain (His & Avi)	SARS-CoV-2	E. coli
	Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i...
TMPY-06504	SARS-CoV-2 (BA.2) Spike S1 NTD Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 (BA.2) Spike S1 NTD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.09 kDa and the accession number is YP_009724390.1.
TMPY-05763	SARS-CoV-2 Spike S1 NTD Protein (hFc & Avi)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (hFc & Avi) is expressed in HEK293 mammalian cells. The predicted molecular weight is 61.74 kDa and the accession number is A0A6G7K2L4.
TMPY-05765	SARS-CoV-2 Spike S1 NTD Protein (hFc & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 61.74 kDa and the accession number is A0A6G7K2L4.
TMPY-05764	SARS-CoV-2 Spike S1 NTD Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.89 kDa and the accession number is A0A6G7K2L4.
TMPY-06371	SARS-CoV-2 B.1.1.529 (Omicron) Spike S1 NTD Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 B.1.1.529 (Omicron) Spike S1 NTD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.68 kDa and the accession number is YP_009724390.1.
TMPY-06122	SARS-CoV-2 Spike S1 NTD Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (L18F & D80A & D215G & LAL242-244 deletion & R246I, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.9 kDa and the accession number is A0A6G7K...
TMPY-06422	SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.10 kDa and the accession number is A0A6G7K2L...
TMPK-01496	HLA-A01:01&B2M&CT83 (NTD*NNLAVY) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01494	HLA-A01:01&B2M&CT83 (NTD*NNLAVY) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPJ-00758	AFP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitaminD (Gc) protein, and alpha-albumin. AFP is a major plasma protein produced by the yolk sac and the li...