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T33766 |
OAB-14
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OAB 14,OAB14 |
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OAB-14 is a Bexarotene derivative that improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the e... |
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T1049L |
Oxybutynin
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Oxytrol,Ditropan,Oxibutyninum |
Potassium Channel
,
AChR
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Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome. |
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T9419 |
Fesoterodine
|
(R) Fesoterodine |
AChR
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Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB). |
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T4612 |
NS309
|
|
EGFR
,
Potassium Channel
,
HER
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NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat... |
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T1049 |
Oxybutynin chloride
|
Oxybutynin hydrochloride,Oxybutynin HCl |
Potassium Channel
,
AChR
|
|
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. |
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T1475 |
Fesoterodine fumarate
|
Toviaz,SPM 907 |
AChR
|
|
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo... |
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T19783 |
Dehydroabiethylamine
|
NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine |
P450
,
PDK
|
|
Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity. |
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T125012 |
7-Oxodehydroabietinol
|
|
|
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7-Oxodehydroabietinol is a useful organic compound for research related to life sciences and the catalog number is T125012. |
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T16370 |
OABK hydrochloride
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Others
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OABK hydrochloride is a small-molecule switch. It also can be used to control protein activity. |
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T74094 |
5,6-Dihydroabiraterone
|
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|
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5,6-Dihydroabiraterone, a metabolic derivative of Abiraterone, is a potent and irreversible inhibitor of CYP17A1, exhibiting antiandrogen and antitumor activities, particularly effective against castration-resistant pros... |
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T40750 |
12,14-Dichlorodehydroabietic acid
|
|
|
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12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, funct... |
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T40751 |
12-Chlorodehydroabietic acid
|
|
|
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12-Chlorodehydroabietic acid is a chlorinated resin acid. |
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T124573 |
Methyl 15-hydroxy-7-oxodehydroabietate
|
|
|
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Methyl 15-hydroxy-7-oxodehydroabietate is a useful organic compound for research related to life sciences and the catalog number is T124573. |
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T126227 |
16-Nor-7,15-dioxodehydroabietic acid
|
|
|
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16-Nor-7,15-dioxodehydroabietic acid is a useful organic compound for research related to life sciences and the catalog number is T126227. |
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T126441 |
Methyl 7β,15-dihydroxydehydroabietate
|
|
|
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Methyl 7β,15-dihydroxydehydroabietate is a useful organic compound for research related to life sciences and the catalog number is T126441. |
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T39306 |
7-Oxodehydroabietic acid
|
|
|
|
7-Oxodehydroabietic acid is a diterpene resin acid found in the roots of Pinus densiflora pine. It acts as a defensive compound against herbivorous insects by disrupting their endocrine system. |
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T40564 |
Neoabietic acid
|
|
|
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Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris . Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro. |
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T126378 |
Isoabsouline
|
|
|
|
Isoabsouline is a useful organic compound for research related to life sciences and the catalog number is T126378. |
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T5023 |
Propiverine hydrochloride
|
|
Others
,
Calcium Channel
,
AChR
|
|
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB). |
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T11275 |
Fesoterodine L-mandelate
|
|
Others
|
|
Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB). |
|
T35052 |
Vibegron
|
MK4618,MK 4618,MK-4618 |
|
|
Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB). |
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T29208 |
ZD-0947
|
AZD0947,AZD-0947,ZD 0947,AZD 0947 |
|
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ZD-0947, a K(ATP) channel activator, is used potentially for the treatment of overactive bladder (OAB). |
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T34774 |
TAK-259 HCl
|
TAK-259,TAK259 |
|
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TAK-259 is a novel, selective, and orally active α1D adrenergic receptor antagonist (α1D, Ki = 1.1 nM) that represents a promising new therapeutic agent for the treatment of symptoms of OAB. It has an anti-frequency effe... |
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T61438 |
Propiverine
|
|
|
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Propiverine is a potent antimuscarinic agent that effectively inhibits cellular calcium influx, leading to the reduction of muscle spasm. It exhibits neurotropic and musculotropic effects specifically on the smooth muscl... |
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T61357 |
EP3 antagonist 3
|
|
|
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EP3 antagonist 3 (compound 2) is a highly effective and specific antagonist of the EP3 receptor. It displays significant oral bioavailability and exhibits a strong pKi value of 8.3. Furthermore, EP3 antagonist 3 possesse... |
