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Search Results for " PEM "

ターゲット

32

阻害剤

8

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T1425 Pemirolast potassium BMY 26517,TWT-8152 Histamine Receptor
Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx i...
T68126 Pemedolac Dexpemedolac COX
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.
T0296 Pempidine 1,2,2,6,6-Pentamethylpiperidine,Perolysen,Pyrilene Others , AChR
Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.
T0396 Pipemidic acid Acido pipemidico Antibacterial , Antibiotic
Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.
T27322 Fispemifene HM-101,HM 101,HM101 Others
Fispemifene (HM-101) is an estrogen receptor modulator (SERM) used to treat genitourinary syndromes and vaginal atrophy.
T0189L Pemetrexed disodium LY-231514,LY231514 disodium,Pemetrexed Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b...
TQ0107 Pemafibrate (R)-K-13675 PPAR
Pemafibrate ((R)-K-13675) is a highly specific PPARα agonist (EC50: 1 nM).
T15461 Halopemide Others , Phospholipase , Dopamine Receptor
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research.
T6226 Pemetrexed disodium hemipenta hydrate Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 6...
T9908 Pembrolizumab PD-1/PD-L1
Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ...
T12401 Pemigatinib INCB054828 FGFR
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).
T0189 Pemetrexed Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).
T74111 N-Methyl pemetrexed
N-Methyl pemetrexed, an impurity found in Pemetrexed, serves as an antifolate cytotoxic agent utilized in cancer research [1].
T60950 Pirepemat fumarate
Pirepemat (IRL752) fumarate can be used in Parkinson's disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2].
T70583 Pemetrexed Diethyl Ester
Pemetrexed Diethyl Ester is a protected intermediate in the synthesis of Pemetrexed, a multi-targeted anti-folate that inhibits thymidylate synthase as well as other folate dependent enzymes.
T66032 Pemetrexed disodium heptahydrate
Pemetrexed disodium is a guanine-derived antineoplastic agent that functions as a nucleic acid synthesis inhibitor through its binding to, and inhibition of, thymidylate synthase.
T25929 Pemetrexed tromethamine Pemetrexed ditromethamine dihydrate
Pemetrexed tromethamine is a chemotherapy drug used for pleural mesothelioma and non-small cell lung cancer.
T74421 Pemvidutide
Pemvidutide, a dual GLP-1R/GCGR agonist, significantly lowers body weight, liver fat, and serum lipids, holding promise for non-alcoholic steatohepatitis (NASH) and obesity research [1].
TMIH-0422 Pemafibrate-d7
Pemafibrate-d7 is a deuterated compound of Pemafibrate. Pemafibrate has a CAS number of 848259-27-8. Pemafibrate is a highly specific PPARα agonist (EC50: 1 nM).
T12329 Ospemifene D4 FC-1271a D4 Estrogen/progestogen Receptor
Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor.
T10817 Cipemastat Ro 32-3555 Others
Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).
T38610 Pirepemat IRL752
Pirepemat (IRL752) is a cortical-preferring catecholamine agent that enhances cognition. It is utilized in the investigation of Parkinson's disease.
T78658 Pemvidutide TFA
Pemvidutide (TFA), a GLP-1R/GCGR dual agonist, effectively reduces body weight, liver fat, and serum lipid levels, and is utilized in research on non-alcoholic steatohepatitis (NASH) and obesity [1].
T60289 Pemirolast
Pemirolast is an orally active antiallergic agent. Pemirolast attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides, that can be used for bronchial asthma and conjunc...
T69191 Pemaglitazar
Pemaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.
T40860 Ivospemin
Ivospemin is an antineoplastic spermine analog.
T77156 Depemokimab
Depemokimab (GSK-3511294) is a long-acting monoclonal antibody targeting IL-15, utilized in asthma research [1] [2].
T13814 Pemafibrate (racemate) K13675 (racemate) Others
Pemafibrate racemate is the racemate of pemafibrate
T70125 Pemrametostat succinate
Pemrametostat succinate is an orally active, potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models.
TMIH-0414 Ospemifene-d4
Ospemifene-d4 is a deuterated compound of Ospemifene. Ospemifene has a CAS number of 128607-22-7. Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate t...
T68992 Pempidine HCl
Pempidine HCl is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more speci...
T69120 Pempidine tartrate
Pempidine tartrate is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more ...

Compounds

Pemirolast potassium
T1425
Synonym: BMY 26517,TWT-8152
Target: Histamine Receptor
Pemedolac
T68126
Synonym: Dexpemedolac
Target: COX
Pempidine
T0296
Synonym: 1,2,2,6,6-Pentamethylpiperidine,Perolysen,Pyrilene
Target: Others, AChR
Pipemidic acid
T0396
Synonym: Acido pipemidico
Target: Antibacterial, Antibiotic
Fispemifene
T27322
Synonym: HM-101,HM 101,HM101
Target: Others
Pemetrexed disodium
T0189L
Synonym: LY-231514,LY231514 disodium,Pemetrexed
Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy
Pemafibrate
TQ0107
Synonym: (R)-K-13675
Target: PPAR
Halopemide
T15461
Synonym:
Target: Others, Phospholipase, Dopamine Receptor
Pemetrexed disodium hemipenta hydrate
T6226
Synonym: Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate
Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy
Pembrolizumab
T9908
Synonym:
Target: PD-1/PD-L1
Pemigatinib
T12401
Synonym: INCB054828
Target: FGFR
Pemetrexed
T0189
Synonym: Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate
Target: DHFR, DNA/RNA Synthesis, Antifolate, Autophagy
N-Methyl pemetrexed
T74111
Synonym:
Target:
Pirepemat fumarate
T60950
Synonym:
Target:
Pemetrexed Diethyl Ester
T70583
Synonym:
Target:
Pemetrexed disodium heptahydrate
T66032
Synonym:
Target:
Pemetrexed tromethamine
T25929
Synonym: Pemetrexed ditromethamine dihydrate
Target:
Pemvidutide
T74421
Synonym:
Target:
Pemafibrate-d7
TMIH-0422
Synonym:
Target:
Ospemifene D4
T12329
Synonym: FC-1271a D4
Target: Estrogen/progestogen Receptor
Cipemastat
T10817
Synonym: Ro 32-3555
Target: Others
Pirepemat
T38610
Synonym: IRL752
Target:
Pemvidutide TFA
T78658
Synonym:
Target:
Pemirolast
T60289
Synonym:
Target:
Pemaglitazar
T69191
Synonym:
Target:
Ivospemin
T40860
Synonym:
Target:
Depemokimab
T77156
Synonym:
Target:
Pemafibrate (racemate)
T13814
Synonym: K13675 (racemate)
Target: Others
Pemrametostat succinate
T70125
Synonym:
Target:
Ospemifene-d4
TMIH-0414
Synonym:
Target:
Pempidine HCl
T68992
Synonym:
Target:
Pempidine tartrate
T69120
Synonym:
Target:

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04340 Mucin-1/MUC1 Protein, Human, Recombinant Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.4 kDa and the accession number is P15941-11.
TMPY-02005 Mucin-1/MUC1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42 kDa and the accession number is P15941-11.
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire...
TMPY-06707 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-00155 Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated Human HEK293 Cells
Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ...
TMPY-06833 Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His) Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.28 kDa and the accession number is P15941-1.
TMPY-06832 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His) Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.19 kDa and the accession number is P15941-1.
TMPY-02871 Mucin-1/MUC1 Protein, Human, Recombinant (mFc) Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41 kDa and the accession number is P15941-11.