Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 22,500 | |||
10 mg | 在庫あり | ¥ 35,500 | |||
25 mg | 在庫あり | ¥ 66,000 | |||
50 mg | 在庫あり | ¥ 103,500 | |||
100 mg | 在庫あり | ¥ 137,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively). |
ターゲット&IC50 | FGFR4:30 nM, FGFR3:1.2 nM, FGFR1:0.4 nM, FGFR2:0.5 nM |
In vitro | In cells expressing FGFR2-CLIP1 fusion are sensitive to Pemigatinib (INCB054828; IC50 value of 10.16 nM)[3]. |
別名 | INCB054828 |
分子量 | 487.5 |
分子式 | C24H27F2N5O4 |
CAS No. | 1513857-77-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.88 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Pemigatinib 1513857-77-6 Angiogenesis Tyrosine Kinase/Adaptors FGFR Fibroblast growth factor receptor INCB054828 inhibit cholangiocarcinoma Orally INCB 054828 INCB-054828 Inhibitor antineoplastic inhibitor