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Search Results for " PTX "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T83638	IR820-PTX		Others
	IR820-PTX is a nanoparticle composed of IR-820 and paclitaxel that is highly permeable and tumor-targeting.IR820-PTX can be used for near-infrared fluorescence imaging and tumor diagnostics.9-cis-Retinoic Acetylcholine (...		Others
T19699	Triciribine phosphate	TCN-P,VD 002,VQD-002	Apoptosis , Akt
	Triciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia.		Apoptosis , Akt
T16413	OTX008	Calixarene 0118,PTX008	Galectin
	OTX008 (PTX008) is a selective galectin-1 inhibitor.		Galectin
T34056	PhTX-343 TFA	(S)-PhTX 343,PhTX-343,(S)-PTX 343,(S)-Philanthotoxin 343,PhTX= 343
	PhTX-343, also known as Philanthotoxin 343, is synthetic analogue of Philanthotoxin 433. PhTX-343 blocks NMDA-gated ion channels; synthetic analog of the wasp polyamine amide toxin δ-philanthotoxin.
T80042	GpTx-1		Sodium Channel
	GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].		Sodium Channel
T69976	WS-691
	WS-691 is a highly Potent and Orally Active ABCB1 Modulator. WS-691 significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC50 = 22.02 nM). WS-691 significantly increased the...
T36896	6α-hydroxy Paclitaxel	6alpha-hydroxypaclitaxel	Drug Metabolite
	6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.		Drug Metabolite
T64016	WS-898
	WS-898 is a potent inhibitor of ABCB1 that reverses resistance to paclitaxel (PTX) in drug-resistant SW620/Ad300, KB-C2 and HEK293/ABCB1 cells with IC50 values of 5.0, 3.67 and 3.68 nM, respectively.
T63267	P-gp/BCRP-IN-1
	P-gp/BCRP-IN-1 (compound 19) is a relatively safe, orally active, and efficient inhibitor of the efflux transporters P-gp and BCRP. By inhibiting their efflux function, it reverses resistance and enhances the oral bioava...
T69162	Ki23057
	Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treatin...
T72473	NOD1/2 antagonist-1
	NOD1/2 Antagonist-1 is a potent dual inhibitor of nucleotide-binding oligomerization domain-like receptors 1 and 2 (NOD1/2), displaying inhibitory concentrations (IC50) of 1.13 μM for NOD1 and 0.77 μM for NOD2. It exhibi...

Compounds

Triciribine phosphate

T19699

Synonym: TCN-P,VD 002,VQD-002

Target: Apoptosis, Akt

OTX008

T16413

Synonym: Calixarene 0118,PTX008

Target: Galectin

PhTX-343 TFA

T34056

Synonym: (S)-PhTX 343,PhTX-343,(S)-PTX 343,(S)-Philanthotoxin 343,PhTX= 343

Target: Sodium Channel

6α-hydroxy Paclitaxel

T36896

Synonym: 6alpha-hydroxypaclitaxel

Target: Drug Metabolite

カタログ番号	製品名	別名	ターゲット
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T37219	N-Palmitoyl Glycine
	The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolam...

天然物製品

Pentoxifylline

T0070

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00207	PTX S1 Protein, Bordetella pertussis, Recombinant (His)	Bordetella pertussis	P. pastoris (Yeast)
	S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the a...
TMPY-03195	Serum Amyloid P Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743.
TMPY-03363	C-Reactive Protein Protein, Human, Recombinant	Human	HEK293 Cells
	C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
TMPK-00114	C-Reactive Protein /CRP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPK-00765	Pentraxin 2/SAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human ...
TMPY-01816	Pentraxin 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin dom...
TMPK-00113	Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human ...
TMPY-06808	Serum Amyloid P Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743.
TMPY-06937	C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.3 kDa and the accession number is P02741-1.
TMPY-05336	C-Reactive Protein Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	C-Reactive Protein Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
TMPK-01333	C-Reactive Protein /CRP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-02200	Peroxiredoxin 2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P32119.
TMPH-02807	NPTXR Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPH-02808	NPTX1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPY-05000	NPTXR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NPTXR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.8 kDa and the accession number is O95502.
TMPJ-00981	PTX3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory...
TMPJ-01130	NPTX1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co‑expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) a...
TMPY-06779	NPTX2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NPTX2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.41 kDa and the accession number is P47972.