|
T10379 |
Arzoxifene hydrochloride
|
SERM 3,LY 353381 HCl |
Others
|
|
Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue. |
|
T2544 |
Bazedoxifene acetate
|
WAY-TES 424,TSE 424,WAY-140424 |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM). |
|
T0835 |
Tamoxifen Citrate
|
Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate |
Apoptosis
,
Estrogen Receptor/ERR
,
HSP
,
Estrogen/progestogen Receptor
,
Autophagy
|
|
Tamoxifen is an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). |
|
T6404 |
Bazedoxifene hydrochloride
|
Bazedoxifene HCl,TSE-424 |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
Bazedoxifene hydrochloride (TSE-424) is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively. |
|
T6906 |
Tamoxifen
|
ICI 46474,Z-Tamoxifen,trans-Tamoxifen,ICI47699 |
Apoptosis
,
Estrogen Receptor/ERR
,
HSP
,
Estrogen/progestogen Receptor
,
Autophagy
|
|
Tamoxifen (ICI47699) is a selective and orally effective estrogen receptor modulator (SERM). Tamoxifen has both inhibitory (e.g., mammary cells) and activating (e.g., bone, liver, and uterine cells) activity against estr... |
|
T73702 |
Mecasermin
|
|
|
|
Mecasermin (Human IGF-I; FK 780), a recombinant form of human insulin-like growth factor I (IGF-I), holds promise for investigating growth failure attributed to growth hormone (GH) insensitivity, which may be due to defe... |
|
T26186 |
Sermetacin
|
Sermetacina,SH G 318 AB,SHG 318 AB,TVX 3158 |
|
|
Sermetacin is an anti-inflammatory agent. |
|
T25534 |
Indazole-Cl
|
Indazole Cl |
Estrogen/progestogen Receptor
|
|
Indazole-Cl is a selective ERß agonist and a selective estrogen receptor modifier (SERM). |
|
T3645 |
Endoxifen E-isomer hydrochloride
|
E-Endoxifen hydrochloride |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride) , a tamoxifen metabolite, is effective specific Estrogen Response Modifier (SERM). |
|
T27322 |
Fispemifene
|
HM-101,HM 101,HM101 |
Others
|
|
Fispemifene (HM-101) is an estrogen receptor modulator (SERM) used to treat genitourinary syndromes and vaginal atrophy. |
|
T4420 |
4-Hydroxytamoxifen
|
ICI 79280,(Z)-4-hydroxy Tamoxifen,trans-4-Hydroxytamoxifen |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer rese... |
|
T15249 |
Estrogen receptor modulator 1
|
|
Estrogen Receptor/ERR
|
|
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4... |
|
T2569 |
Chlorotrianisene
|
tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
,
COX
|
|
Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but... |
|
T7839 |
Lasofoxifene Tartrate
|
CP-336156 |
Estrogen Receptor/ERR
|
|
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator. |
|
T0139 |
Toremifene
|
GTx 006,Z-Toremifene |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
Toremifene (GTx 006) is a selective estrogen-receptor modulator (SERM). |
|
T28957 |
TFR4OHT
|
TFR-4-OHT,TFR 4 OHT |
|
|
TFR4OHT is a selective ER modulator (SERM). |
|
T25700L |
Levormeloxifene fumarate
|
|
|
|
Levormeloxifene fumarate is an osteoporosis drug and selective estrogen receptor modulator (SERM). |
|
T27946 |
LY-329146
|
LY 329146 |
|
|
LY-329146 is a selective estrogen receptor modulator (SERM). LY-329146 prevents doxorubicin resistance in tumor cells expressing multidrug resistance-associated protein (MRP) by inhibiting the binding of MRP substrates t... |
|
T62119 |
Lasofoxifene
|
|
|
|
Lasofoxifene (CP-336156) is a selective, orally active estrogen receptor modulator (SERM) that inhibits the growth and metastasis of primary tumours and is also anti-osteoporotic. |
|
T13076 |
Tamoxifen-d5
|
ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5 |
HSP
|
|
Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen is a selective modulator of estrogen receptor (SERM). Tamoxifen is a potent activator of Hsp90 and enhances the Hsp90 molecular chaperone ATPase activity. |
|
T21375 |
Clomifene
|
Omifin,D,Chloramiphene,Clomiphene,Clomiphene free base,Citrate |
|
|
Clomifene is a selective estrogen receptor modulator (SERM), it has both estrogenic and anti-estrogenic activities. This agent causes the release of the pituitary gonadotropins follicle-stimulating hormone (FSH) and lute... |
|
T39259 |
Arzoxifene
|
LY353381,Arzoxifene,SERMIII |
|
|
Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator (SERM) exhibiting a fixed ring structure analogous to raloxifene. This compound demonstrates potent antiestrogenic effects on breast cancer ... |
|
T79382 |
ER degrader 6
|
|
Estrogen Receptor/ERR
|
|
ER degrader 6 (compound 35s) is a potent selective estrogen receptor modulator (SERM) with the capacity to degrade Estrogen Receptor (ER)α. It disrupts the microtubule network, inhibiting tubulin polymerization, and effe... |
|
TMIH-0414 |
Ospemifene-d4
|
|
|
|
Ospemifene-d4 is a deuterated compound of Ospemifene. Ospemifene has a CAS number of 128607-22-7. Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate t... |
|
T71578 |
Endoxifen mesylate
|
|
|
|
Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and ot... |
|
T20419 |
Raloxifene
|
Pharoxifene,Raloxifenum,Keoxifene,LY-139481 |
Estrogen Receptor/ERR
,
Others
|
|
Raloxifene (LY-139481) is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk. |
