3
2
13
1
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21694 | (R)-Lisofylline | (R)-Lisophylline | STAT |
(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat... | |||
T21729 | (±)-Lisofylline | Others | |
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent. | |||
T22148 | (S)-Lisofylline | Others | |
(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5681 | ETHYL CAFFEATE | ETHYL 3,4-DIHYDROXYCINNAMATE | NF-κB , COX , PGE Synthase , NO Synthase |
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s... | |||
T3S0013 | Ethyl trans-caffeate | Ethyl caffeate,Caffeic Acid Ethyl Ester | Others |
1. Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) has anti-inflammatory activity. 2. Ethyl trans-caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl trans-caffeate is a... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02581 | STAT4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription f... | |||
TMPY-01767 | IL-12RB2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleu... | |||
TMPY-04793 | IL-35 Protein, Human, Recombinant (Flag & His) | Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ... | |||
TMPH-01558 | IL12RB2 Protein, Human, Recombinant (His) | Human | Yeast |
Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenoty... | |||
TMPH-01777 | TYK2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin... | |||
TMPH-01778 | TYK2 Protein, Human, Recombinant (His) | Human | Baculovirus |
Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin... | |||
TMPY-06105 | IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His) | Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ... | |||
TMPY-03879 | IL-35 Protein, Human, Recombinant | Human | HEK293 |
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ... | |||
TMPJ-00398 | IL-12RB2 Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits tha... | |||
TMPY-06428 | IL-12RB2 Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 |
Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleu... | |||
TMPY-01409 | IL-12A Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ... | |||
TMPY-00838 | IL-12A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ... | |||
TMPY-04105 | IL-12A Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L3700 | JAK-STAT Compound Library | 252 compounds | |
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening; |