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Search Results for " STAT4 "

ターゲット

3

阻害剤

2

天然化合物

13

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T21694 (R)-Lisofylline (R)-Lisophylline STAT
(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat...
T21729 (±)-Lisofylline Others
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.
T22148 (S)-Lisofylline Others
(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes.
カタログ番号 製品名 別名 ターゲット
T5681 ETHYL CAFFEATE ETHYL 3,4-DIHYDROXYCINNAMATE NF-κB , COX , PGE Synthase , NO Synthase
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...
T3S0013 Ethyl trans-caffeate Ethyl caffeate,Caffeic Acid Ethyl Ester Others
1. Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) has anti-inflammatory activity. 2. Ethyl trans-caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl trans-caffeate is a...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02581 STAT4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription f...
TMPY-01767 IL-12RB2 Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleu...
TMPY-04793 IL-35 Protein, Human, Recombinant (Flag & His) Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPH-01558 IL12RB2 Protein, Human, Recombinant (His) Human Yeast
Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenoty...
TMPH-01777 TYK2 Protein, Human, Recombinant (E. coli, His) Human E. coli
Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin...
TMPH-01778 TYK2 Protein, Human, Recombinant (His) Human Baculovirus
Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin...
TMPY-06105 IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His) Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPY-03879 IL-35 Protein, Human, Recombinant Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPJ-00398 IL-12RB2 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits tha...
TMPY-06428 IL-12RB2 Protein, Cynomolgus, Recombinant (mFc) Cynomolgus HEK293
Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleu...
TMPY-01409 IL-12A Protein, Human, Recombinant (His) Human HEK293
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ...
TMPY-00838 IL-12A Protein, Human, Recombinant (hFc) Human HEK293
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ...
TMPY-04105 IL-12A Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 ...
カタログ番号 製品名
L3700 JAK-STAT Compound Library

252 compounds
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;