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T35903 |
N-acetyl Dapsone
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Antibacterial
,
Parasite
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N-acetyl Dapsone is an anti-inflammatory and antimicrobial compound widely used in the treatment of leprosy, malaria, acne and various immune disorders. |
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T7195 |
GSK369796 Dihydrochloride
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N-tert-butylisoquine |
Potassium Channel
,
Parasite
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GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization(IC50 of 7.5 μM) |
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T5493 |
Pyronaridine
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Others
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Pyronaridine is an orally active, mannitol-containing anti-malarial compound that acts by interfering with the replication of the malaria parasite (Plasmodium) within red blood cells. Pyronaridine is often used in combin... |
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T4382 |
Proguanil hydrochloride
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Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil |
Others
,
Dehydrogenase
,
DNA/RNA Synthesis
,
Antifolate
,
Parasite
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Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine ... |
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T0860L |
Mefloquine
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Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 |
Others
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Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l... |
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T10685L |
Carpaine hydrochloride
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Others
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Carpaine hydrochloride, an alkaloid isolated from Carica papaya Linn, has anti-thrombocytopenic activity. It has the anti-plasmodial activity to prevent malaria. |
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T60411 |
Primaquine
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Primaquine is the generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the potent gametocytocide in falciparum malaria [1] [2]. |
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TMIH-0362 |
N-Acetyl Dapsone-d4
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N-Acetyl Dapsone-d4 is a deuterated compound of N-Acetyl Dapsone. N-Acetyl Dapsone has a CAS number of 565-20-8. N-acetyl Dapsone is an anti-inflammatory and antimicrobial compound widely used in the treatment of leprosy... |
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T64286 |
Quinidine polygalacturonate
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Quinidine polygalacturonate is a potent, selective, orally active inhibitor of cytochrome P450db (cytochrome P450db) and a potent K+channel blocker with an IC50 value of 19.9 μM, which also induces apoptosis. Quinidine p... |
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T61971 |
CHMFL-PI4K-127
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CHMFL-PI4K-127 (compound 15g) is a highly selective inhibitor of PfPI4K (Plasmodium falciparum PI4K kinase) with oral activity (IC50=0.9 nM). CHMFL-PI4K-127 shows strong inhibitory activity against Plasmodium falciparum ... |
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TMIH-0457 |
Proguanil-d6 HCl
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|
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Proguanil-d6 HCl is a deuterated compound of Proguanil HCl. Proguanil HCl has a CAS number of 637-32-1. Proguanil Hydrochloride is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria a... |
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TMIH-0146 |
Chloroquine-d5
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Chloroquine-d5 is a deuterated compound of Chloroquine. Chloroquine has a CAS number of 54-05-7. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory ... |
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T78184 |
MMV009085
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MMV009085 is a potent inhibitor of the Plasmodium falciparum hexose transporter (Pf HT1), with potential as an anti-malarial agent. It also inhibits the human glucose transporter, demonstrating high potency with an IC50 ... |
