ホーム 計算ツール
代理店ログイン
製品 阻害剤 ライブラリー リコンビナントタンパク質 キット サービス お問い合わせ
ペプチド 抗体 色素試薬 PROTAC バーチャルスクリーニング TargetMolキット Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails 天然化合物 フェノール類 アルカロイド類 フラボノイド類
阻害剤 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK
膜輸送体・イオンチャネル 代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム 幹細胞 チロシンキナーゼ・アダプター ユビキチン PROTAC
化合物ライブラリー 生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー 天然化合物ライブラリー HTS用天然物ライブラリー 分野別 天然化合物ライブラリー 天然物誘導体ライブラリー CADD用天然物ライブラリー ドラッグライク 化合物ライブラリー フラグメントライブラリー カスタム化合物ライブラリー
シグナル伝達経路 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル
DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK 膜輸送体・イオンチャネル
代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム
幹細胞 チロシンキナーゼ・アダプター ユビキチン その他 PROTAC
生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー
天然化合物ライブラリー HTS用天然物ライブラリー 分野別 天然化合物ライブラリー 天然物誘導体ライブラリー CADD用天然物ライブラリー
ドラッグライク 化合物ライブラリー ドラッグライクライブラリー
フラグメントライブラリー ゼネラルフラグメントライブラリー 特徴的なフラグメントライブラリー カスタム化合物ライブラリー
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

検索結果

Search Results for " chymotrypsin-like "

ターゲット

Proteasome

27

阻害剤

3

天然化合物

23

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T17011 TCH-165 Proteasome
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.
T6027 Delanzomib CEP-18770 Apoptosis , NF-κB , Proteasome
Delanzomib (CEP-18770) is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and peptidylglutamyl activities of the proteosome.
T21854 Proteasome inhibitor IX PS-IX,AM114 Proteasome
Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). Proteasome inhibitor IX shows potent anticancer activity. Proteasome inhibitor IX exhibits HCT116 p53+/+ c...
T6941 PI-1840 PI 1840 PARP , Proteasome
PI-1840（IC50 = 27 nM）is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
T7016 VR23 Apoptosis , Proteasome , Caspase
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.
T63321 20S Proteasome activator 1 Proteasome
20S Proteasome activator 1 is a 20S proteasome activator with IC50 of 0.3 μM for trypsin-like sites, 0.7 μM for chymotrypsin-like sites and 1.8 μM for caspase sites. 20S Proteasome activator 1 prevents the accumulation o...
T8350 TPCK Proteasome
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis
T2016 MLN9708 Ixazomib Citrate Proteasome
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 (Ixazomib Citrate) is MLN2238 in aqueous solutions or plasma.
T2122 Ixazomib MLN2238 Proteasome , Caspase , Autophagy
Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also i...
T21617 MG-115 Z-LL-Nva-CHO Proteasome
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteas...
T36352 Suc-Leu-Tyr-AMC
Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; em...
T26202 SP-Chymostatin B alpha-Mapi
SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. I...
TP1308 Suc-Leu-Leu-Val-Tyr-AMC
Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases.
T37418 Z-LLL-AMC
Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core. Chymotrypsin-like activity can be quantified by fluorescent detection of free AMC (also known as 7-am...
T80102 Z-Leu-Leu-Tyr-COCHO Proteasome
Z-Leu-Leu-Tyr-COCHO is a potent inhibitor of chymotrypsin-like activity, exhibiting a Ki value of 3.0 nM [1].
T62080 GSK3494245
GSK3494245 (DDD01305143) is a potent, selective, orally active inhibitor of chymotrypsin-like activity that binds to the proteasome of WTL.donovani at an IC50 of 0.16 μM, sandwiched between the β4 and β5 subunits. GSK349...
T36338 AAF-CMK (trifluoroacetate salt)
Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μ...
T81711 N-Acetyl-DL-phenylalanine β-naphthyl ester
N-Acetyl-DL-phenylalanine β-naphthyl ester serves as a chromogenic substrate specifically for chymotrypsin and microbial serine proteases like subtilisin [1]. This aromatic amino acid ester exhibits color changes upon en...
T81372 Proteasome-activating peptide 1
Proteasome-activating peptide 1 enhances chymotrypsin-like proteasomal catalytic activity, boosting proteolytic rates both in vitro and within cultured cells. Additionally, it inhibits protein aggregation in a cellular m...
T74878 Enzyme-IN-1
Enzyme-IN-1 (compound 1), a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases, specifically targets and inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. This compound may possess pot...
T78640 Z-LLF-CHO Z-Leu-Leu-Phe-CHO Proteasome
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM. Additionally, this compound serves as an inhibitor of NF-κB ...
T63760 3CPLro-IN-2
3CPLro-IN-2 is a potent, orally active inhibitor of SARS-CoV-2 3CLpro (IC50: 1.55 μM, Ki: 6.09 μM). 3-Chymotrypsin-like cysteine protease (3CLpro) is an essential protein for viral replication and is a potential drug tar...
T76243 Proteasome-activating peptide 1 TFA
Proteasome-activating peptide 1 TFA is a potent activator of the proteasome, enhancing chymotrypsin-like proteasomal catalytic activity and thereby increasing proteolytic rates both in vitro and in culture. Additionally,...
T62479 3CPLro-IN-1
3CPLro-IN-1 (compound A17) is a potent, orally active inhibitor of SARS-CoV-2 3CLpro (IC50: 5.65 μM). 3-Chymotrypsin-like cysteine protease (3CLpro), a protein essential for viral replication, is an attractive drug targe...
T80735 Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO Proteasome
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) of 1.5 µM, 2.3 µM, and 40.5 µM for branched-chain amino acid-p...
T73986 ONX-0914 TFA
ONX-0914 (PR-957) TFA is a selective, noncompetitive, irreversible inhibitor targeting the chymotrypsin-like subunit (LMP7) of the immunoproteasome, effectively blocking cytokine production and mitigating the progression...
T69288 CEP-7055
CEP-18770 is an orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome, with potential antineoplastic activity. Proteasome inhibitor CEP 18770 represses the ...
カタログ番号 製品名 別名 ターゲット
TN3228 7-Hydroxy-3-(4-hydroxybenzyl)chroman Others
7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome.
T10238 Aclacinomycin A hydrochloride Aclarubicin hydrochloride Proteasome
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinom...
TN5655 Broussonin B
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsi...

天然物製品

7-Hydroxy-3-(4-hydroxybenzyl)chroman
TN3228
Synonym:
Target: Others
Aclacinomycin A hydrochloride
T10238
Synonym: Aclarubicin hydrochloride
Target: Proteasome
Broussonin B
TN5655
Synonym:
Target:

Recombinant Proteins

Species：
Human (10)
Mouse (9)
Borrelia burgdorferi (1)
E. coli (1)
Rat (1)
SARS-CoV-2 (1)
Expression System：
E. coli (11)
HEK293 Cells (7)
Baculovirus Insect Cells (3)
P. pastoris (Yeast) (2)
Tag：
His (7)
N-6xHis (5)
N-10xHis, C-Myc (3)
C-His (2)
N-6xHis, C-Myc (2)
N-6xHis-SUMO (2)
C-6xHis (1)
Tag Free (1)
カタログ番号 製品名 Species Expression System
TMPY-03653 CTRL Protein, Human, Recombinant (His) Human HEK293 Cells
CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is...
TMPH-01093 CELA2A Protein, Human, Recombinant (E. coli, His) Human E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-01094 CELA2A Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-01095 CELA2B Protein, Human, Recombinant (His & SUMO) Human E. coli
Acts upon elastin. CELA2B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.8 kDa and the accession number is P08218.
TMPH-02582 CELA2A Protein, Mouse, Recombinant (His) Mouse E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPJ-00481 CELA3A Protein, Human, Recombinant (His) Human HEK293 Cells
Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymoge...
TMPH-02584 CELA3B Protein, Mouse, Recombinant (His & Myc) Mouse P. pastoris (Yeast)
Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Mouse, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 29.6 kD...
TMPH-01097 CELA3B Protein, Human, Recombinant (His) Human E. coli
Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32....
TMPH-02583 CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc) Mouse E. coli
Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predict...
TMPH-01096 CELA3A Protein, Human, Recombinant (His & SUMO) Human E. coli
Efficient protease with alanine specificity but only little elastolytic activity. CELA3A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular w...
TMPH-00582 Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPH-00209 CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc) Borrelia burgdorferi E. coli
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPH-03329 Mcpt2 Protein, Rat, Recombinant (His & Myc) Rat E. coli
This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates....
TMPH-02778 Mcpt4 Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala...
TMPY-01363 Serpin A11 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPJ-01431 SARS-CoV-2 Papain-Like Protease Protein SARS-CoV-2 E. coli
Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a pap...
TMPY-01855 Serpin A10 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPI...
TMPY-01841 Serpin I2 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPY-02712 Serpin B3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPY-01589 Serpin B10 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-01632 Serpin B4 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-01893 Serpin A12 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin,...
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I...
CTRL Protein, Human, Recombinant (His)
TMPY-03653
Species: Human
Expression System: HEK293 Cells
CELA2A Protein, Human, Recombinant (E. coli, His)
TMPH-01093
Species: Human
Expression System: E. coli
CELA2A Protein, Human, Recombinant (His)
TMPH-01094
Species: Human
Expression System: P. pastoris (Yeast)
CELA2B Protein, Human, Recombinant (His & SUMO)
TMPH-01095
Species: Human
Expression System: E. coli
CELA2A Protein, Mouse, Recombinant (His)
TMPH-02582
Species: Mouse
Expression System: E. coli
CELA3A Protein, Human, Recombinant (His)
TMPJ-00481
Species: Human
Expression System: HEK293 Cells
CELA3B Protein, Mouse, Recombinant (His & Myc)
TMPH-02584
Species: Mouse
Expression System: P. pastoris (Yeast)
CELA3B Protein, Human, Recombinant (His)
TMPH-01097
Species: Human
Expression System: E. coli
CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc)
TMPH-02583
Species: Mouse
Expression System: E. coli
CELA3A Protein, Human, Recombinant (His & SUMO)
TMPH-01096
Species: Human
Expression System: E. coli
Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc)
TMPH-00582
Species: E. coli
Expression System: E. coli
CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc)
TMPH-00209
Species: Borrelia burgdorferi
Expression System: E. coli
Mcpt2 Protein, Rat, Recombinant (His & Myc)
TMPH-03329
Species: Rat
Expression System: E. coli
Mcpt4 Protein, Mouse, Recombinant (E. coli, His)
TMPH-02778
Species: Mouse
Expression System: E. coli
Serpin A11 Protein, Mouse, Recombinant (His)
TMPY-01363
Species: Mouse
Expression System: HEK293 Cells
SARS-CoV-2 Papain-Like Protease Protein
TMPJ-01431
Species: SARS-CoV-2
Expression System: E. coli
Serpin A10 Protein, Mouse, Recombinant (His)
TMPY-01855
Species: Mouse
Expression System: HEK293 Cells
Serpin I2 Protein, Human, Recombinant (His)
TMPY-01841
Species: Human
Expression System: HEK293 Cells
Serpin B3 Protein, Human, Recombinant (His)
TMPY-02712
Species: Human
Expression System: Baculovirus Insect Cells
Serpin B10 Protein, Mouse, Recombinant (His)
TMPY-01589
Species: Mouse
Expression System: Baculovirus Insect Cells
Serpin B4 Protein, Mouse, Recombinant (His)
TMPY-01632
Species: Mouse
Expression System: Baculovirus Insect Cells
Serpin A12 Protein, Human, Recombinant (His)
TMPY-01893
Species: Human
Expression System: HEK293 Cells
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
TMPY-01027
Species: Mouse
Expression System: HEK293 Cells
カタログ番号 製品名
L1710 Anti-COVID-19 Compound Library

1133 compounds
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents；

ライブラリー

Anti-COVID-19 Compound Library
L1710
Compounds: 1133
TARGETMOLについて
会社情報 プライバシー保護について イベント＆ニュース 利用規約
サポート
お問い合わせ 代理店情報 品質管理 技術サポート
技術資料
製品カタログ 引用文献 シグナル伝達経路 溶解計算
ニュースレター登録
ニュースレターで最新の製品情報やお得な情報をお届けします。
ニュースレターで最新の製品情報やお得な情報をお届けします。
TargetMolについて
サポート
技術資料
本ウェブサイトに掲載されている製品は全て研究用試薬です。研究目的以外の用途にはご使用できません。
Copyright © 2015-2023 TargetMol Chemicals Inc. All rights reserved.