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Search Results for " hyperlipidemic "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
T24865	Tenivastatin	L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid	ROS , HMG-CoA Reductase
	Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia.		ROS , HMG-CoA Reductase
T4179	Probucol disuccinate		LDL
	Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.		LDL
T68030	Acitemate	Chinoin 123	Others
	Acitemate(Chinoin 123) has an inhibitory effect on atherosclerosis and reduces the permeability of the aorta in rabbits fed a hyperlipidemic diet, which can be used to study atherosclerosis.		Others
T16240	N,N'-Diacetyl-L-cystine	(Ac-Cys-OH)2,DiNAC	Others
	N,N'-Diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL...		Others
T61430	S-2E
	S-2E is a compound that functions as an orally active, noncompetitive inhibitor of both HMG-CoA reductase and acetyl-CoA carboxylase. It exhibits an anti-hyperlipidemic action, making it suitable for studying conditions ...
T21814	ONO 4817
	ONO-4817 is a broad-spectrum matrix metalloproteinase (MMP) inhibitor that potentially mitigates atherosclerotic neointimal proliferation and atheromatous plaque progression by suppressing matrix metalloproteinases (MMPs...
T64171	LXR antagonist 2
	LXR antagonist 2 (compound 10rr) is a potent LXR (liver X receptor) inverse agonist, acting on LXRβ (IC50: 0.36 μM) and LXRα (IC50: 2.25 μM). LXR antagonist 2 is an adipogenesis inhibitor that downregulates LXR target ge...

Compounds

YM-750

T23550

Synonym: YM 750

Target: Acyltransferase

Tenivastatin

T24865

Synonym: L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid

Target: ROS, HMG-CoA Reductase

N,N'-Diacetyl-L-cystine

T16240

Synonym: (Ac-Cys-OH)2,DiNAC

カタログ番号	製品名	別名	ターゲット
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
T8158	Tilianin		Others
	Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.		Others
T0254	Probucol	DH-581	Virus Protease , ABC , Lipid
	Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.		Virus Protease , ABC , Lipid
TN1438	Beta-Amyrin acetate		Antioxidant , HMG-CoA Reductase , Epoxide Hydrolase , Antifungal
	beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
T5S0662	Gelsemine	Gelsemin	Antioxidant
	1. Gelsemine (Gelsemin) has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cance...		Antioxidant
T7529	Yamogenin		Others
	Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.		Others
TN1097	β-Boswellic acid	Beta-boswellic acid	Lipoxygenase , DNA/RNA Synthesis
	β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.		Lipoxygenase , DNA/RNA Synthesis
T83562	(2R)-Flavanomarein
	'(2R)-Flavanomarein, a major flavonoid from Coreopsis tinctoria Nutt, exhibits protective effects against diabetic nephropathy and possesses antioxidative, antidiabetic, antihypertensive, and anti-hyperlipidemic properti...

天然物製品

Target: Virus Protease, ABC, Lipid

beta-Amyrin acetate

TN1438

Synonym:

Target: Antioxidant, HMG-CoA Reductase, Epoxide Hydrolase, Antifungal

Synonym: Beta-boswellic acid

Target: Lipoxygenase, DNA/RNA Synthesis

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02686	PON3 Protein, Human, Recombinant (S50N, His)	Human	Baculovirus Insect Cells
	PON3 was enriched in the mitochondria-associated membrane fraction of hepatocytes. PON3 deficiency resulted in impaired mitochondrial respiration, increased mitochondrial superoxide levels, and increased hepatic expressi...

PON3 Protein, Human, Recombinant (S50N, His)

TMPY-02686

Species: Human

Expression System: Baculovirus Insect Cells