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T1698 |
Carvedilol EP IMpurity E
|
Carvedilol USP E,Carvedilol Impurity E |
Others
|
|
Carvedilol EP IMpurity E (Carvedilol USP E) is used as a pharmaceutical intermediate. |
|
T1733 |
Ciprofloxacin EP IMpurity A
|
Q-Acid,Fluoroquinolonic Acid,Ciprofloxacin Impurity A |
Antibiotic
|
|
Ciprofloxacin EP IMpurity A (Fluoroquinolonic Acid) is an antibiotic and antimicrobial agent. |
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T8752 |
BAR 501 impurity
|
|
GPCR19
|
|
BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase act... |
|
T11007L |
Levofloxacin Hydrochloride Impurity A
|
Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base) |
Antibacterial
|
|
Levofloxacin Hydrochloride Impurity A I, one of the quinolones, has a broad spectrum of antibacterial action. |
|
T31204 |
Darapladib-impurity
|
|
Others
|
|
Darapladib-impurity is the impurity of Darapladib. Darapladib inhibits lipoprotein-associated phospholipase A2 (Lp-PLA2). |
|
T9042 |
Teriflunomide impurity 3
|
4-Amino-N-(4-trifluoromethylphenyl)benzamide |
COX
|
|
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM). |
|
T12962 |
Sofosbuvir impurity G
|
|
HCV Protease
|
|
Sofosbuvir impurity G is a diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
|
T0667 |
Flecainide Impurity D
|
|
Others
|
|
Flecainide Impurity D is used as an intermediate in industry. |
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T1690 |
BroMhexine IMpurity B
|
|
Others
|
|
Bromhexine Impurity B reagent used in the preparation of Ambroxol and Bromhexine (B678600) metabolites Ambroxol EP Impurity E. |
|
T67853 |
Rivaroxaban Impurity
|
Rivaroxaban-10 |
Factor Xa
|
|
Rivaroxaban Impurity (Rivaroxaban-10) is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM. |
|
T0550 |
Domperidone EP Impurity A
|
|
Others
|
|
Domperidone EP Impurity A is used as pharmaceutical intermediates. |
|
T1357 |
TriMetazidine EP IMpurity-D
|
|
Others
|
|
TriMetazidine EP Impurity-D is the starting material for the synthesis of TriMetazidine and an intermediate for the synthesis of various compounds. |
|
T3097 |
Mycophenolic Acid Impurity
|
5,7-dihydroxy-4-methylphthalide |
Others
|
|
Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part... |
|
T1689 |
Enalapril IMpurity B
|
(+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine |
Others
|
|
Enalapril IMpurity B ((+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine) is Moexipril intermediate and is the main metabolite of Imidapril. |
|
T4196 |
Betahistine EP Impurity C
|
NSC19005 |
Others
,
Histamine Receptor
|
|
Betahistine EP Impurity C (NSC19005) is structurally related to Betahistine. Betahistine EP Impurity C is a dimer of Betahistine. |
|
T12961 |
Sofosbuvir impurity F
|
Sofosbuvir 3',5'-Bis-(S)-phosphate |
HCV Protease
|
|
Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA replication. |
|
T9084 |
Cetirizine Impurity B dihydrochloride
|
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride |
Histamine Receptor
|
|
Cetirizine Impurity B dihydrochloride (De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride) is an impurity of Cetirizine dihydrochloride. Cetirizine is a second-generation antihistamine. Cetirizine is a specific, o... |
|
T21113 |
N2-Acetylaciclovir
|
Aciclovir EP Impurity F |
Antibacterial
|
|
N2-Acetylaciclovir (Aciclovir EP Impurity F) is a derivative of the antiviral compound Aciclovir, which has selective T-cell immunotoxicity. |
|
T32550 |
Lamivudine impurity A RS
|
Lamivudine impurity A,Lamivudine specified impurity A |
|
|
Lamivudine impurity A RS is a bioactive chemical. |
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T39031 |
Olmesartan impurity
|
|
|
|
Olmesartan impurity, a compound related to Olmesartan, is an angiotensin II receptor (AT1R) antagonist utilized in the study of high blood pressure. Olmesartan (RNH-6270) is the parent compound with similar properties an... |
|
T20997 |
Amlodipine besilate impurity B
|
Amlodipine EP Impurity B |
|
|
Amlodipine besilate impurity B is a biochemical. |
|
T20995 |
Amlodipine besilate impurity D
|
Amlodipine Related Compound A,Amlodipine impurity A |
|
|
Amlodipine besilate impurity D is a biochemical. |
|
T2692 |
A40926
|
Dalbavancin Impurity |
Antibacterial
|
|
A40926 (Dalbavancin Impurity) is effective against Gram positive bacteria. |
|
T37026 |
Mesalamine impurity P
|
|
|
|
Mesalamine impurity P is an impurity of Mesalamine . 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1].
[1]. Kyle Dammann, et al.PAK1 modulat... |
|
T37704 |
Olanzapine Lactam Impurity
|
|
|
|
Olanzapine lactam impurity is a potential impurity found in commercial preparations of olanzapine.1It is a degradation product formed by exposure to thermal or oxidative stress.
1.Baertschi, S.W., Brunner, H., Bunnell, C... |
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T37628 |
Ibuprofen impurity 1
|
|
|
|
Ibuprofen impurity 1 is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].
[1]. Noreen Y, et al. Development of a radiochemical c... |
|
T35430 |
Afatinib impurity 11
|
|
|
|
Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1].
[1]. Li D... |
|
T37176 |
Edoxaban impurity 6
|
|
|
|
Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaba... |
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T40785 |
Gefitinib impurity 1
|
|
|
|
Gefitinib impurity 1 is a compound derived from Gefitinib, a potent and selective EGFR tyrosine kinase inhibitor (IC 50 = 33 nM). This orally active compound selectively inhibits tumor cell growth stimulated by EGF (IC 5... |
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T36076 |
Ciprofibrate impurity A
|
|
|
|
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1].
[1]. Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation ... |
|
T40941 |
Olmesartan lactone impurity
|
|
|
|
Olmesartan lactone impurity is a cyclic ester impurity derived from Olmesartan, which is an angiotensin II receptor (AT1R) antagonist with potential applications in the study of high blood pressure. |
|
T1364 |
7-Aminodeacetoxycephalosporanic acid
|
7-ADCA,Cephalexin Impurity B,Cefalexine EP IMpurity B,Deacetoxycephalosporanic Acid,7-Aminodesacetoxycephalosporanic acid |
Antibiotic
|
|
7-Aminodeacetoxycephalosporanic acid (Cefalexine EP IMpurity B) is used as an antibiotic. |
|
T36592 |
Impurity of Calcipotriol
|
|
|
|
Impurity of Calcipotriol is an impurity in calcipotriol, a synthetic VitD3 analog. |
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T35728 |
Hydrochlorothiazide Impurity C
|
|
|
|
Hydrochlorothiazide impurity C is a potential impurity found in commercial hydrochlorothiazide preparations. [1] Hydrochlorothiazide is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter ... |
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T36945 |
Cetirizine Impurity C
|
|
|
|
Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine is a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. It acts as a specific, orally active, and long-acting antagonist of the ... |
|
T37175 |
Edoxaban impurity 4
|
|
|
|
Edoxaban impurity 4, an impurity of Edoxaban (DU-176), is a selective, potent, and orally active inhibitor of factor Xa (FXa), exhibiting Kis of 0.561 nM for free FXa and 2.98 nM for prothrombinase. As an anticoagulant a... |
|
T40752 |
Ibuprofen Impurity F
|
|
|
|
Ibuprofen Impurity F is a known impurity of Ibuprofen, which acts as an anti-inflammatory inhibitor that selectively targets both COX-1 and COX-2 enzymes. It exhibits inhibitory activity with IC50 values of 13 μM and 370... |
|
T40537 |
Ibuprofen Impurity K
|
|
|
|
Ibuprofen Impurity K is a compound that serves as an impurity in Ibuprofen. Ibuprofen itself is an anti-inflammatory inhibitor specifically designed to target COX-1 and COX-2. It exhibits inhibitory activity with IC50 va... |
|
T35876 |
Chlorthalidone Impurity G
|
|
|
|
Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotran... |
|
T0614 |
4-Amino-5-Chloro-2-Methoxybenzoic Acid
|
Metoclopramide EP Impurity C |
Others
|
|
4-Amino-5-Chloro-2-Methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite. |
|
T36006 |
Olmesartan medoxomil impurity C
|
|
|
|
Olmesartan medoxomil impurity C is an impurity of Olmesartan medoxomil, a potent and selective angiotensin AT1 receptor inhibitor with an IC50 of 66.2 μM. |
|
T10957 |
Dapagliflozin impurity
|
|
Others
|
|
Dapagliflozin impurity is the enantiomer of Dapagliflozin, Dapagliflozin is a sodium glucose transporter 2 inhibitor. |
|
T39885 |
Captopril EP Impurity E
|
|
|
|
Captopril EP Impurity E is an impurity of Captopril. Captopril, also known as SQ-14534, is an orally active angiotensin-converting enzyme (ACE) inhibitor that contains a thiol group. It has antihypertensive properties an... |
|
T20996 |
Amlodipine besilate impurity E
|
Amlodipine Diethyl Ester,Amlodipine EP Impurity E,Amlodipine USP Related Compound E |
|
|
Amlodipine besilate impurity E is a biochemical. |
|
T29998 |
Amlodipine besilate impurity F
|
Amlodipine Dimethyl Ester,Amlodipine USP Related Compound F,Amlodipine EP Impurity F |
|
|
Amlodipine besilate impurity F, also known as Amlodipine Dimethyl Ester, is a biochemical. |
|
T2025 |
HDAC-IN-7
|
HBI-8000,CS055,Chidamide impurity |
HDAC
|
|
HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable inhibitor of HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10). |
|
T12960 |
Sofosbuvir impurity E
|
|
Others
|
|
Sofosbuvir impurity E is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity. |
|
T12957 |
Sofosbuvir impurity B
|
|
Others
|
|
Sofosbuvir impurity B is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity. |
|
T12534 |
Prasugrel chloride impurity
|
|
Others
|
|
Prasugrel chloride impurity is an orally active antagonist of P2Y12 receptor, and inhibits ADP-induced platelet aggregation. |
|
T12967 |
Sofosbuvir impurity L
|
|
HCV Protease
|
|
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity. |
