|
T64722 |
IP Lysis Buffer
|
|
Others
|
|
IP Lysis Buffer is a useful organic compound for research related to life sciences and the catalog number is T64722. |
|
T64696 |
NP-40 Cell Lysis Buffer
|
|
Others
|
|
NP-40 Cell Lysis Buffer is a useful organic compound for research related to life sciences and the catalog number is T64696. |
|
T8129 |
Potassium acetate
|
Diuretic salt,Potassium ethanoate |
Antifungal
|
|
Potassium acetate (Diuretic salt) with antibacterial and antifungal properties. |
|
T6622 |
Oxacillin sodium monohydrate
|
Stapenor monohydrate,Sodium oxacillin monohydrate,Methicillin,Bactocill monohydrate |
Others
,
Antibacterial
,
Antibiotic
|
|
Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class. |
|
T30099 |
Aplysistatin
|
|
Others
|
|
Aplysistatin is a bromosesquiterpene derived from sea mollusks. |
|
T28537 |
Ricasetron
|
Brl 46470,Brl46470,Brl-46470 |
5-HT Receptor
|
|
Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysis and antiemetic properties, and is used in the study of anxiety and anxiety disorders. |
|
T60442 |
NLRP3/AIM2-IN-3
|
|
NOD
,
AIM2
|
|
NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of N... |
|
T23764 |
AZ3976
|
AZ 3976,AZ-3976 |
PAI-1
|
|
AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities. |
|
T7338L |
DHBP
|
Benzoresorcinol |
Others
|
|
DHBP (Benzoresorcinol) is an WalKR TCS activator. It works via targeting walk and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain. |
|
T22831 |
Protein kinase inhibitor H-7 dihydrochloride
|
H-7 dihydrochloride |
PKC
|
|
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-... |
|
T12470 |
Picloxydine
|
|
Antibacterial
|
|
Picloxydine is a heterocyclic biguanide with antiplaque and antibacterial activity. |
|
T1497 |
Liranaftate
|
Piritetrate,M-732 |
Antifungal
|
|
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ... |
|
T1005L |
Amoxicillin trihydrate
|
Amoxycillin trihydrate,Amoxil trihydrate,Amoxipen trihydrate,Moxaline trihydrate |
Antibacterial
,
Antibiotic
|
|
Amoxicillin trihydrate (Moxaline trihydrate) binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Amoxicillin trihydrate is a broad-spectrum, semisyntheti... |
|
T0953 |
Cefazolin sodium
|
Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin |
Others
,
Antibacterial
,
Antibiotic
|
|
Cefazolin sodium (cephazolin sodium) salt binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin sodium salt is the sodium salt of cefazolin, a beta... |
|
T1625 |
Lomefloxacin hydrochloride
|
Lomefloxacin HCl,Okacyn,Maxaquin |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during... |
|
T1224 |
Cefuroxime sodium
|
Anaptivan,Cefuroxime sodium salt,Biociclin |
Antibacterial
,
Antibiotic
|
|
Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime... |
|
T1213 |
Piperacillin sodium
|
Sodium piperacillin,CL227193,Piperacillin sodium salt |
Antibacterial
,
Antibiotic
|
|
(CL227193) )binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis. Piperacilli... |
|
T1005 |
Amoxicillin
|
Amoxycillin |
Antibacterial
,
Antibiotic
|
|
Amoxicillin (Amoxycillin) binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Amoxicillin Anhydrous is the anhydrous form of a broad-spectrum, semisynthet... |
|
T1122 |
Cephalothin sodium
|
Cefalotin sodium,Cephalothin,Cefalotin |
Antibacterial
,
Antibiotic
|
|
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a... |
|
T82252 |
GTPγS tetralithium
|
|
Others
|
|
GTPγS (tetralithium) is a G-protein activator known for its role in preventing proteolytic degradation of proteins, facilitating tyrosine kinase-dependent GLUT4 translocation, stimulating phospholipases, and promoting ac... |
|
T1187 |
Bifonazole
|
Bay H-4502 |
P450
,
Antibiotic
,
Antifungal
|
|
Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essent... |
|
T0932 |
Cefixime
|
FK-027,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635 |
Antibacterial
,
Antibiotic
|
|
Cefixime (FR-17027) is a broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lact... |
|
T1063 |
Ticarcillin disodium
|
Ticarpen,Ticarcillin disodium salt |
Antibacterial
,
Antibiotic
|
|
Ticarcillin disodium (Ticarpen) is the disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Similar to carbenicillin in action... |
|
T1228 |
Cefonicid sodium
|
Monocid sodium,Cefonicid disodium salt |
Antibacterial
,
Antibiotic
|
|
Cefonicid binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Cefonicid sodium (Monocid sodium) is the sodium salt form of cefonicid, a semisynthetic seco... |
|
T3934 |
Isavuconazonium sulfate
|
|
Antifungal
|
|
Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), wh... |
|
T69454 |
Cephradine dihydrate
|
|
Others
|
|
Cephradine dihydrate is the hydrate form of Cephradine (free base), a semi-synthetic cephalosporin antibiotic. Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding pr... |
|
T69070 |
Cephradine sodium
|
|
Others
|
|
Cephradine sodium is the salt form of Cephradine (free base), a semi-synthetic cephalosporin antibiotic. Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins... |
|
T36049 |
Linearmycin B
|
|
Others
|
|
Linearmycin B is a polyene antibiotic that has been found inStreptomyces.1It induces lysis and degradation ofB. subtilisas a component ofStreptomycesMg1 extract.2
1.Sakuda, S., Guce-Bigol, U., Itoh, M., et al.Novel linea... |
|
T81338 |
Pyrromethene 556
|
PM556 |
|
|
Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye utilized in researching membrane fusion, lysis, and gap-junctional communication, as well as in monitoring cell and liposome volume alterations. |
|
T77878 |
Desthiobiotin-Iodoacetamide
|
|
Others
|
|
Desthiobiotin-Iodoacetamide serves as an ADC (Antibody-Drug Conjugate) Linker and functions as a probe for labeling cell lysis in Oridonin-treated cells [1]. |
|
T81517 |
PEP1
|
|
|
|
PEP1 is a biologically active peptide that interacts with POPC supported lipid bilayers (SLBs), binding at low concentrations, while higher concentrations induce POPC SLB lysis. |
|
T81337 |
Pyrromethene 650
|
PM650 |
|
|
Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye employed for studying membrane fusion, lysis, and gap-junctional communication, as well as for detecting volume changes in cells or liposomes. |
|
T36048 |
Linearmycin A
|
|
Others
|
|
Linearmycin A is a polyene antibiotic that has been found inStreptomyces.1It is active against the bacteriaS. aureusandE. coli(MICs = 3.1 and 1.6 μg/disc, respectively), the fungiS. cerevisiaeandC. albicans(MICs = 0.1 an... |
|
T35579 |
PKSI-527
|
|
Others
|
|
PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respect... |
|
T80762 |
XmAb 5592
|
|
|
|
XmAb 5592 is a humanized, Fc-engineered antibody targeting HM1.24 with improved affinity for both FcγRIIIa and FcγRIIa receptors. It enhances lysis of HM1.24-specific multiple myeloma (MM) cells through both antibody-dep... |
|
T77127 |
Pacanalotamab
|
|
|
|
Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) that specifically targets BCMA (B cell maturation antigen) and CD3ɛ. By redirecting T cells to cells expressing BCMA on their surface, Pacanalotama... |
|
T83490 |
[Lys3]-Bombesin
|
|
|
|
[Lys3]-Bombesin is a biologically active peptide used in PET (Positron Emission Tomography) imaging to identify GRPR (gastrin-releasing peptide receptor) positive prostate cancer. The compound, when conjugated with a cor... |
|
T72113 |
6-Aminocaproic acid hydrochloride
|
EACA hydrochloride,EACA hydrochloride ; Epsilon-Amino-n-caproic Acid hydrochloride ; 6-Aminohexanoic acid hydrochloride,6-Aminohexanoic acid hydrochloride,Epsilon-Amino-n-caproic Acid hydrochloride |
Others
|
|
6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid derivative, serves as a potent, orally active antifibrinolytic agent by inhibiting plasmin and plasminogen. It functions through competitive binding to lysin... |
|
T76881 |
Teclistamab
|
|
|
|
Teclistamab, a human bispecific antibody targeting both BCMA on target cells and CD3 on T cells, facilitates T cell-mediated cytotoxicity, which results in T cell activation and subsequent target cell lysis. This compoun... |
|
T38296 |
Alamethicin F50
|
Alamethicin F50 |
Others
|
|
Alamethicin F50 is a peptaibol isolated from Trichoderma. It is a polymer of 20 amino acids that includes modified and non-proteinogenic amino acids. Alamethicin F50 is a mixture of 13 different peptides, with the most a... |
|
T76880 |
Tepoditamab
|
|
|
|
Tepoditamab (MCLA-117) is a bispecific monoclonal antibody designed to target CLEC12A on myeloid cells and CD3 on cytotoxic T cells. CLEC12A serves as a myeloid differentiation antigen. The compound effectively eliminate... |
|
T14566 |
BI-9627
|
|
Sodium Channel
|
|
BI-9627 is a selective and potent sodium hydrogen exchange isomer 1 (NHE1) inhibitor.BI-9627 partially reverses the effects of DMA with IC50 values of 6 and 31 nM in the intracellular pH recovery (pHi) and human platelet... |
|
T38103 |
Defensin HNP-3 (human) (trifluoroacetate salt)
|
|
|
|
Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth o... |
|
T69350 |
Ethionamide HCl
|
|
Others
|
|
Ethionamide HCl is the salt form of Ethionamide, a second-line antitubercular agent that inhibits mycolic acid synthesis. Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis.... |
|
T76843 |
Tebentafusp
|
|
|
|
Tebentafusp (IMCgp100) is a bispecific fusion protein designed to target the gp100 peptide-HLA-A*02:01 complex, a melanoma-associated antigen. It directs T cells towards melanoma cells expressing gp100 through a high-aff... |
|
T79739 |
CYP51/PD-L1-IN-2
|
|
Others
|
|
CYP51/PD-L1-IN-2 (compound L20), a quinazoline with antifungal properties, is a potent dual inhibitor targeting both CYP51 (IC50: 0.263 μM) and PD-L1 (IC50: 0.017 μM). The compound promotes early apoptosis in the fungal ... |
|
T69266 |
Cefcanel free acid
|
|
Others
|
|
Cefcanel is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcanel is active against the species E. coli, K. aerogenes and Proteus mirabilis; H. influenzae and M. catarrhalis has reasonable ... |
|
T79738 |
CYP51/PD-L1-IN-1
|
|
Others
|
|
CYP51/PD-L1-IN-1 (compound L11), a quinazoline with antifungal properties, simultaneously inhibits CYP51 (IC50: 0.884 μM) and PD-L1 (IC50: 0.083 μM). This compound prompts early apoptosis in the fungal cell cycle, marked... |
|
T79740 |
CYP51/PD-L1-IN-3
|
|
Others
|
|
CYP51/PD-L1-IN-3 (compound L21), a quinazoline with antifungal properties, serves as a dual inhibitor targeting CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM). This compound promotes early fungal apoptosis within the ... |
|
T37873 |
CAP 3
|
|
Others
|
|
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increas... |
