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T11064 |
DMT1 blocker 2
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Others
|
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DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo. |
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T20984 |
Lumogallion
|
4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid |
Others
|
|
Lumogallion (4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid) is an azo reagent used in the determination of metal ions, such as the research of V, Fe, and Al. |
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T39477 |
Ca-DTPA trisodium salt hydrate
|
Ca-DTPA trisodium salt hydrate,Calcium trinatrium diethylenetriaminepentaacetic acid hydrate |
Others
|
|
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Ca-DTPA tris... |
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T0420 |
Pentetic Acid
|
Acidum penteticum,Detarex,Detapac,DTPA,diethylenetriaminepentaacetic acid |
Others
|
|
Pentetic Acid (Detarex) is an edetate and a chelating agent used in preparing radiopharmaceuticals. |
|
T2096 |
Framycetin sulfate
|
Neomycin Sulphate B,Framycetin sulphate |
Antibacterial
,
Antibiotic
|
|
Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds. |
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T38476 |
Metallo β-lactamase ligand 1
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|
Antibacterial
|
|
Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities. |
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T60694 |
Metallo-β-lactamase-IN-4
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|
|
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Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1]. |
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T72261 |
Metallo-β-lactamase-IN-9
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|
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Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1]. |
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T60239 |
Metallo-β-lactamase-IN-6
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|
|
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Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lac... |
|
T40816 |
Metalaxyl-M
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Metalaxyl-M,(R)-Metalaxyl |
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Metalaxyl-M ((R)-Metalaxyl), the active (R)-enantiomer of Metalaxyl, is a broad-spectrum fungicide that targets protein and ribosomal RNA synthesis in fungi. It is employed in the research of plant diseases attributed to... |
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T60914 |
Metallo-β-lactamase-IN-8
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|
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Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity. The IC50 values of Metallo-β-lactamase-IN-8 against L1, Imi... |
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T60282 |
Metallo-β-lactamase-IN-3
|
|
|
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Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor that has the potential to restore the activity of current β-lactam antibiotics and to offer an orthogonal strategy to the discovery ... |
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T20066 |
Metalaxyl
|
Ridomil 72WP,Allegiance,CGA48988,CGA-48988,CGA 48988,Metalaxil |
|
|
Metalaxyl is an acylalanine fungicide with systemic function. It can be used to control Pythium in a number of vegetable crops, and Phytophthora in peas. |
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T60370 |
Metallo-β-lactamase-IN-2
|
|
|
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Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for IMP-7, respectively [1]. |
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T79435 |
Metallo-β-lactamase-IN-11
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|
|
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Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against the bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At a concentration of 10 µM, ... |
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T60494 |
Metallo-β-lactamase-IN-7
|
|
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Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM -Type metallo-β-lactamase with IC 50 s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacter... |
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T61173 |
Metallo-β-lactamase-IN-5
|
|
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Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactama... |
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T31479 |
Diisopropyl xanthogen disulfide
|
NSC1339,NSC 1339,Isopropylxanthic disulfide,NSC-1339 |
Others
|
|
Diisopropyl xanthogen disulfide (NSC-1339) can be used to synthesize a proligand for metal complexes related to the molybdenum cofactor. |
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T9241 |
O-Cresolphthalein Complexone
|
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Others
|
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o-Cresolphthalein Complexone is a metal complexing indicator and an acid-base indicator. |
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T19936 |
Xantphos
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|
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Xantphos, a ligand in the coupling reaction of Buchwald, Suzuki and others, is a metal chelating ligand that can be used to catalyze the reaction. |
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T15213 |
Emeramide
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BDTH2 |
Reactive Oxygen Species
|
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Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator. |
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T65167 |
EDTA copper(II) disodium salt
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Antibiotic
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EDTA copper(II) disodium salt is a metal chelator with antimicrobial, anti-inflammatory and antioxidant activity, slows down damage caused by metal ions, maintains osmotic pressure during protein purification, and can be... |
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T73718 |
MDCG sodium
|
NOX 100 sodium,N-methyl-N-dithiocarboxyglucamine sodium |
Endogenous Metabolite
|
|
MDCG sodium (N-methyl-N-dithiocarboxyglucamine sodium) is a metal chelator that promotes biliary excretion of Cd. |
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T20736 |
Cryptating agent 222
|
Cryptate 222,NSC 264495,NSC-264495,NSC264495 |
Others
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Cryptating agent 222 (NSC-264495) is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion and forms ligands with metal cations. |
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T0423 |
Ethylenediaminetetraacetic acid trisodium salt
|
Edetate Trisodium,ethylenediaminetetraacetic acid Trisodium,EDTA Trisodium,Trisodium EDTA,Edetate Trisodium,EDTA trisodium salt |
Others
,
Ferroptosis
|
|
Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy. |
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T22402 |
Potassium thioacetate
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Others
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Potassium thioacetate has been employed for the synthesis of polymers, heterocycles, nanoparticles, transition-metal ligands, bioactive compounds and macromolecular inclusion complexes. |
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T3952 |
TPEN
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TPEDA |
Apoptosis
,
Reactive Oxygen Species
,
Autophagy
|
|
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. |
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T8813 |
Tetrakis (4-carboxyphenyl) porphyrin
|
TCPP,Tetracarboxyphenylporphine |
Others
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Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover.Tetrakis (4-carboxyphenyl) porphyrin is a fabricated three dimensional Ru polymer complex. It can be grafted on SiO2/Nb2O5 substrate and subse... |
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T20346 |
Salicylaldoxime
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Others
|
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Salicylaldoxime is a chelating agent sometimes used in the analysis of samples containing transition metal ions, with which it often forms brightly colored coordination complexes. |
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T11063 |
DMT1 blocker 1
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Others
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DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo. |
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T12593 |
Pyrithione
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1-hydroxyl-1H-pyridine-2-thione |
Others
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Pyrithione (1-hydroxyl-1H-pyridine-2-thione) is a transition metal complex, a zinc ionophore, that causes elevated zinc levels in mammalian cells. Pyrithione has potent bactericidal and antifungal activity. |
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T20381 |
Cetyl glycol
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NSC-71525,NSC 71525,NSC71525 |
Others
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Cetyl glycol (NSC-71525) favors the decomposition of the metal-organic precursor, formation of an intermediate Co(2+)Fe(3+)-oleate complex, and the nucleation of nanoparticles at lower temperatures. Cetyl glycol is a red... |
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T5321 |
Itaconic anhydride
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Others
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Itaconic anhydride (ITA) is a biobased material that is obtained from renewable resources. It is widely used in metal adhesion promoter, synthetic resin improver, esterification agent, herbicide, insecticide. |
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T0781 |
Dimercaprol
|
Dicaptol,Dithiopropanol |
Others
,
HIV Protease
|
|
Dimercaprol (Dicaptol) is an anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the t... |
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T0666 |
4-Chlorosalicylic acid
|
4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid |
Tyrosinase
,
Antibacterial
,
Antibiotic
,
Antifungal
|
|
4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) is antimicrobial compositions comprising a metal salt and a benzoic acid analog. |
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T6198 |
Dolutegravir
|
S/GSK1349572,GSK1349572 |
HIV Protease
|
|
Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
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T0664 |
Nicotinic acid hydrazide
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|
Others
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Nicotinic acid hydrazide (NAH) is a hydrazide derivative of nicotinic acid, a heterocyclic organic compound. It is a peroxidase inhibitor and can form solid metal complexes with strong biological activity. |
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T5983 |
O-Phenanthroline
|
1,10-Phenanthroline |
MMP
,
Others
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o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene m... |
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T65636 |
BIS-TRIS propane
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BTP |
Others
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BIS-TRIS propane (BTP), a novel multidentate ligand of nickel- and cobalt-based spin clusters, is a metal chelator. BIS-TRIS propane is often used as a zwitterionic buffer for PCR and protein crystallization studies. |
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T22428 |
Sodium Glucoheptonate
|
Sodium glucoheptonate |
Others
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Sodium Glucoheptonate (Sodium glucoheptonate) is used as a kit for radio-labeling with Tc-99m which is kidney- and brain-imaging agent, and can be used in brain-tumor detection[1][2]. Sodium glucoheptonate is also used f... |
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T8422 |
DIETHYLDITHIOCARBAMIC ACID COPPER SALT
|
Cupric diethyldithiocarbamate |
Others
|
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Diethyldithiocarbamic acid copper salt is a chelating agent used in various metal, protein, and enzyme experiments. It can also serve as a complexing agent for synthesizing various organic compounds, including heterocycl... |
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T50056 |
Antibacterial agent 170
|
|
Others
|
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4-(4,5-dibromo-6-oxo-1,6-dihydropyridazin-1-yl)benzene-1-sulfonamide is a sulfonamide derivative used in the synthesis of building blocks for various supramolecular structures such as metal-organic skeletons and coordina... |
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T66155 |
EDTA, Disodium Salt, Dihydrate
|
Ethylenediaminetetraacetic acid disodium dihydrate |
Protease
|
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EDTA, Disodium Salt, Dihydrate (Ethylenediaminetetraacetic acid disodium dihydrate) is a metal ion chelator used as a protease inhibitor.EDTA, Disodium Salt, Dihydrate is a molecule that is ineffective against cellulase ... |
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T22443 |
Triglycidyl isocyanurate
|
Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI |
Apoptosis
|
|
Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk... |
|
T9524 |
Lanthanum trichloride
|
|
Others
|
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Lanthanum trichloride can be used as an analytical reagent and can be used as a raw material for extracting metal lanthanum and as a petroleum cracking catalyst. Lanthanum chloride also has a certain role in the field of... |
|
T8940 |
KUN56321
|
3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl- |
Others
|
|
KUN56321 (3H-Naphth[1,2-d]imidazole, 2-(4-bromophenyl)-3-phenyl-) is a luminescent agent. The application of KUN56321 comprises: coating the film of KUN56321 onto hole transport layer or electron transport layer of ITO g... |
|
T124358 |
Deferoxamine
|
Deferoxamine B,Desferrioxamine B |
Apoptosis
,
Antioxidant
,
HIF
,
Autophagy
|
|
Deferoxamine（Desferrioxamine B） is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may imp... |
|
T41109 |
Phytochelatin 2 (PC2)
|
|
|
|
Phytochelatin 2, a short plant peptide, serves as an essential metal-binding compound. Phytochelatins are a diverse group of plant compounds that play a crucial role in chelating metals, safeguarding against metal toxici... |
|
T30179 |
Astiron
|
Astyron |
|
|
Astiron is a self-expanding bare-metal nitinol stent. |
|
T20841 |
Nitrilotriacetic acid
|
Nitriloacetate,Nitrilotriacetate |
|
|
Nitrilotriacetic acid is a chelating agent, complexing agent, metal masking agent. |
