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カタログ番号 | 製品名 | 別名 | ターゲット |
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T3146 | BMS-202 | PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2 | Apoptosis , PD-1/PD-L1 |
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction. | |||
T9292 | ALE-0540 | ALE0540 | Others , Trk receptor |
ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA, as well as signal transduction and biological responses mediated by TrkA receptors. | |||
T4236 | AR-M 1000390 hydrochloride | ARM390 Hydrochloride,ARM-390 HCl | Opioid Receptor |
AR-M 1000390 hydrochloride (ARM-390 HCl) , also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic resp... | |||
T26082 | RID-F | Ridaifen-F,Ridaifen F | |
RID-F is an inhibitor of the nonpeptidic proteasome. | |||
T26439 | A 74273 | A-74273,A74273 | |
A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition. | |||
T27661 | JNJ-10329670 | ||
JNJ 10329670 is a highly potent (Ki of approximately 30 nM), nonpeptidic, noncovalent inhibitor of human cathepsin S with immunosuppressive activity. | |||
T33734 | NS 11 | NS-11,NS11 | |
NS 11 is an RGD-nonpeptidic mimetic. | |||
T70946 | SC 51316 | ||
SC 51316 is a nonpeptidic angiotensin II (AII) receptor antagonist. | |||
T69170 | ATC0065 HCl | ||
ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist. | |||
T16851 | SB-267268 | Others | |
SB-267268 inhibits human and mouse αvβ3 (IC50s: 0.68 and 0.29 nM, respectively). SB-267268 is a selective and nonpeptidic alpha(v)beta3 and alpha(v)beta5 integrins antagonist (Kis: 0.9, 0.5 and 0.7 nM for human αvβ3, mon... | |||
T12072 | ML-00253764 hydrochloride | Others | |
ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively). | |||
T14781 | Brilacidin | PMX 30063 | Others |
T11369 | GB-110 | Others | |
GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. | |||
T11630L | IFN alpha-IFNAR-IN-1 | Others | |
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50: 2-8 μM). | |||
T13846 | PROTAC RIPK degrader-2 | Others | |
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation. | |||
T11369L | GB-110 hydrochloride (1252806-70-4 free base) | GB-110 hydrochloride | Others |
GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR... | |||
T61210 | R-PSOP | ||
R-PSOP is a potent and selective nonpeptidic NMUR2 antagonist, exhibiting binding affinity to human and rat NMUR2 with Ki values of 52 nM and 32 nM, respectively. This compound demonstrates moderate central nervous syste... | |||
T73854 | GB-110 hydrochloride | ||
GB-110 hydrochloride, a potent and orally active nonpeptidic agonist of the protease-activated receptor 2 (PAR2), selectively triggers PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM [1]. | |||
T79455 | SARS-CoV-2 Mpro-IN-9 | SARS-CoV | |
SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) and improved physicochemical and drug metabolism and pharma... | |||
T21786 | Apogossypolone (ApoG2) | ||
Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i values of 35, 25 and 660 nM for Bcl-2, Mcl-1 and Bcl-X L, respe... | |||
T36393 | CAY10727 | ||
CAY10727 is an inhibitor of protein arginine deiminase 3 (PAD3; kinact/KI= 15,600 M-1min-1).1It is selective for PAD3 over PAD1, -2, and -4 (kinact/KIs = 360, 1,110, and 1,460 M-1min-1, respectively). 1.Jamali, H., Khan,... | |||
T38372 | 2-Fluoro-4-iodo benzonitrile | ||
2-Fluoro-4-iodo benzonitrile is a building block.1,2It has been used in the synthesis ofL. infantumtrypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.12-Fluoro-4-iodo benzonitrile has a... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T6485 | Embelin | NSC 91874,Emberine,Embelic acid | Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy |
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM). |