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Search Results for " p75 "

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カタログ番号	製品名	別名	ターゲット
T64096	Integrase-LEDGF/p75 allosteric inhibitor 1
	Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. It inhibits HIV-1 DNA integration and exhibits antiviral effects, acting on the HIV-1 recombinant mo...
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
T11861	LM11A-31 dihydrochloride		Others
	LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagoni...		Others
T6712	Tyrphostin AG 879	AG 879	Apoptosis , EGFR , Trk receptor , HER , PDGFR
	Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.		Apoptosis , EGFR , Trk receptor , HER , PDGFR
T9292	ALE-0540	ALE0540	Others , Trk receptor
	ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA, as well as signal transduction and biological responses mediated by TrkA receptors.		Others , Trk receptor
T39755	Pirmitegravir	STP0404	HIV Protease
	Pirmitegravir (STP0404) is a potent and selective inhibitor of allosteric integrase (ALLINI) targeting the LEDGF/p75 binding site. Pirmitegravir inhibits PBMC. Pirmitegravir inhibits PBMC.Pirmitegravir has significant an...		HIV Protease
T74097	THX-B
	THX-B, a potent non-peptidic antagonist of the neurotrophin receptor p75 (p75 NTR), is utilized in the study of diabetic kidney disease, neurodegenerative, and inflammatory disorders [1] [2] [3].
T17314	(±)-BI-D		Others
	(±)-BI-D is an effective ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site (IC50: 2.4–2.9 μM).		Others
T69782	GS-9822
	GS-9822 is a novel LEDGIN, an inhibitor that targets the binding pocket of LEDGF/p75 which is a cellular cofactor that substantially contributes to HIV integration site selection, displaying a block-and-lock phenotype in...
TP2069	BDNF (human)
	Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative ...
T75831	NTR 368 TFA
	NTR 368 TFA, a peptide derived from the p75 neurotrophin receptor (p75NTR) and corresponding to residues 368-381 of the human receptor, exhibits a helix-forming propensity in the presence of micellar lipid. It is a poten...
T76813	Bedinvetmab
	Bedinvetmab (ZTS-00508841), a canine monoclonal antibody (mAb) designed to target nerve growth factor (NGF), prevents NGF from interacting with its receptors, tropomyosin receptor kinase A (trkA) and p75 neurotrophin rec...
T78282	Tanezumab	RN-624,PF 4383119
	Tanezumab (RN-624) is a high-affinity, specific humanized anti-NGF monoclonal antibody (mAb) that inhibits nerve growth factor (NGF) from binding to its p75 and TrkA receptors in the peripheral nervous system. It is util...

Compounds

Integrase-LEDGF/p75 allosteric inhibitor 1

Target: Tyrosinase, transporter, HIV Protease

LM11A-31 dihydrochloride

Target: Apoptosis, EGFR, Trk receptor, HER, PDGFR

ALE-0540

T9292

Synonym: ALE0540

Target: Others, Trk receptor

Synonym: RN-624,PF 4383119

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02614	NGFR/p75NTR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NGFR/p75NTR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P08138.
TMPY-01166	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P20333-1.
TMPY-01697	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119.
TMPY-06862	Siglec-7 Protein, Human, Recombinant(aa 1-353, His)	Human	HEK293 Cells
	Siglec-7 Protein, Human, Recombinant(aa 1-353, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9Y286-1.
TMPJ-00515	HCLS1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Hematopoietic lineage cell-specific protein (HCLS1) is a protein that in humans is encoded by the HCLS1 gene. It is expressed only in tissues and cells of hematopoietic origin. It is substrate of the antigen receptor-cou...
TMPY-02588	NGFR/p75NTR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	NGFR/p75NTR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9Z0W1.
TMPY-02541	NGFR/p75NTR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	NGFR/p75NTR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q9Z0W1.
TMPY-02615	NGFR/p75NTR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NGFR/p75NTR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P08138.
TMPJ-01397	Siglec-7 Protein,Human,Recombinant(aa 19-353, His）	Human	HEK293 Cells
	Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by va...
TMPY-00934	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 53 kDa and the accession number is P20333-1.
TMPY-03881	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (aa 1-268, M196A, His)	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (aa 1-268, M196A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is P20333-2.
TMPY-05814	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P20333-1.
TMPY-06600	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.39 kDa and the accession number is NP_001057.1.
TMPJ-00287	TNF RII Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TNF RII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is P20333.
TMPY-01696	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is P25119.
TMPJ-00288	TNF RII Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	TNF RII Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60 KDa and the accession number is P20333.
TMPK-00321	IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293 Cells
	IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.6 kDa and the accession number i...
TMPK-00320	IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.5 kDa and the accession number is P14784.
TMPY-06959	NGFR/p75NTR Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	NGFR/p75NTR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.34 kDa and the accession number is P07174.
TMPY-04831	NGFR/p75NTR Protein, Rabbit, Recombinant (hFc)	Rabbit	HEK293 Cells
	NGFR/p75NTR Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is XP_008269543.1.
TMPY-04646	NGFR/p75NTR Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
	NGFR/p75NTR Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is XP_008269543.1.
TMPY-06973	NGFR/p75NTR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	NGFR/p75NTR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.03 kDa and the accession number is XP_005583674.1.
TMPJ-01468	Pro-Beta NGF Protein, Human, Recombinant	Human	E. coli
	The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite...
TMPJ-00135	BDNF Protein, Human/Murine/Rat, Recombinant	Human,Mouse,Rat	E. coli
	Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPH-03219	Rabies virus (RABV) (strain India) Glycoprotein (His)	RABV	P. pastoris (Yeast)
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPJ-00134	Pro-BDNF Protein, Human, Recombinant	Human	E. coli
	The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, w...
TMPH-03223	Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)	RABV	Baculovirus Insect Cells
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03220	Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03222	Rabies virus (RABV) (strain ERA) Glycoprotein (His)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03221	Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPH-03224	Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)	RABV	E. coli
	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb...
TMPK-01382	TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa....
TMPJ-01312	TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...