23
2
8
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2391 | Camostat mesylate | FOY-S980,FOY305,Camostat mesilate | Serine/threonin kinase , SARS-CoV , Sodium Channel |
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function. | |||
T34123 | Pranazepide | FR120480,FK 480,FR-120480 | cholecystokinin |
Pranazepide (FK 480) is a small molecule cholecystokinin receptor antagonist used to study digestive disorders and pancreatitis. | |||
T74140 | β-D-Glucan | Others | |
β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis. | |||
T0372 | Gabexate mesylate | FOY | Factor Xa , Serine Protease , Proteasome |
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh... | |||
T9670L | Patamostat HCl | Patamostat HCl(114568-26-2 Free base) | Serine Protease , Protease |
Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50 values of 39 nM, 950 nM, and 1.9 μM, respectively.Patamosta... | |||
T28248 | Ono-3307 mesylate | Ono-3307,Ono3307,Ono 3307 | Protease |
Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar ... | |||
T67749 | Fuzapladib | IS-741 | Phospholipase |
Fuzapladib (IS-741) (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of adhesion molecules (integrin) expressed on the inflammator... | |||
T13662 | Diarylalkane derivative 1 | Others | |
Diarylalkane derivative 1 is used for the research of pancreatitis. | |||
T25275 | Crambene | NSC 321802,NSC-321802,NSC321802 | |
Crambene results in the induction of apoptosis by protects mice against acute pancreatitis via anti-inflammatory pathways. | |||
T78376 | Rimtoregtide | ||
Rimtoregtide, a polypeptide, markedly attenuates the elevations in blood amylase and lipase levels associated with acute pancreatitis, suggesting its potential utility in the research of pancreatitis and acute pancreatit... | |||
T37771 | Taurolithocholic Acid 3-sulfate (sodium salt) | ||
Taurolithocholic acid 3-sulfate (TLCA3S) is a metabolite of the conjugated bile acid taurolithocholic acid . TLCA3S has been used to study bile acid transport in cellular models and to induce pancreatitis in mouse models... | |||
T31569 | DP-b99 | DP-b-99,DP-BAPTA-99,DPb-99,DPBAPTA-99,DP-b 99 | |
DP-B 99 (DP-B 99, DP-BAPTA-99, DPB-99, DP-BAPTA-99) is a potential chelating agent for the treatment of acute pancreatitis. | |||
T33314 | Methantheline Bromide | Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide | |
Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre... | |||
T10055 | (Iso)-FK-480 | CHEMBL333994 | cholecystokinin |
(Iso)-FK-480 is a novel orally available cholecystokinin A (CCK-A) antagonist for investigational treatment of chronic pancreatitis. | |||
T38521 | Patamostat mesylate | E-3123 mesylate | |
Patamostat mesylate (E-3123) is a highly potent protease inhibitor, displaying strong inhibitory activity against trypsin, plasmin, and thrombin, with IC 50 values of 39 nM, 950 nM, and 1.9 μM, respectively. This compoun... | |||
T22506 | 3,4-DAA | NOS | |
3,4-DAA has anti-inflammatory activity, ameliorates acute hepatic allograft injury, and alleviates severe acute pancreatitis by inhibiting intestinal barrier dysfunction and NF-κB activation.3,4-DAA inhibits EOC20 cell-i... | |||
T36623 | Antileukinate | ||
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutro... | |||
T71955 | C3001a | ||
C3001a is a selective activator for TREK, against other two-pore domain K+(K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a targets TREK channels in the peripheral nervous sy... | |||
T79258 | SEH inhibitor-16 | Epoxide Hydrolase | |
sEH Inhibitor-16, a potent soluble epoxide hydrolase (sEH) inhibitor, exhibits an IC50 of 2 nM. It diminishes inflammatory damage associated with cerulein-induced acute pancreatitis (AP) in mice, making it suitable for i... | |||
T28933 | TCV-309 | TCV309 | |
TCV-309 is an inhibitor of platelet activating factor (PAF). TCV-309 reduces graft PMN infiltration and enhances early function of 24-hour-preserved rat kidneys with long warm ischemia. TCV-309 attenuates the priming eff... | |||
T9670 | Patamostat | ||
Patamostat (E-3123) is a potent protease inhibitor that effectively inhibits trypsin, plasmin, and thrombin, exhibiting IC50 values of 39 nM, 950 nM, and 1.9 µM, respectively. Research suggests that Patamostat might supp... | |||
T69035 | Camostat free base | ||
Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or... | |||
T36408 | Rhein-13C4 | Rhein-13C4 | |
Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerei... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8198 | Visnagin | Others | |
Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase. | |||
T5352 | GLYCODEOXYCHOLIC ACID | Others , Endogenous Metabolite | |
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00057 | REG3G Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Pancreatitis-associated protein IB, Regenerating islet-derived protein III-gamma, is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the pancreas and also expressed in test... | |||
TMPY-01897 | PRSS3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on... | |||
TMPJ-00733 | SPINK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise... | |||
TMPJ-00601 | Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His) | Human | E. coli |
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is ... | |||
TMPJ-00796 | Serpin E2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc... | |||
TMPJ-01083 | Serpin E2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea... | |||
TMPY-02480 | Chymotrypsin C Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two... | |||
TMPY-01406 | REG3G Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in var... |