|
T1575 |
Nizatidine
|
Axid,Acinon,Zanizal |
AChE
,
Histamine Receptor
|
|
Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity. |
|
T0081 |
Lafutidine
|
FRG-8813 |
5-HT Receptor
,
Histamine Receptor
|
|
Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion. |
|
T4616 |
Metoclopramide
|
5-Chloro-2-methoxyprocainamide |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ... |
|
T1069 |
Metoclopramide hydrochloride
|
Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
|
T8388 |
Vonoprazan
|
TAK-438 (free base) |
Proton pump
|
|
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis |
|
T8385 |
Metoclopramide hydrochloride hydrate
|
Metoclopramide monohydrochloride monohydrate |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic |
|
T0424 |
Bismuth Subsalicylate
|
Bismuth subsalicylat,Bismuth(III) salicylate basic,Bismuth oxysalicylate |
COX
,
PGE Synthase
|
|
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts ... |
|
T21254 |
Vonoprazan Fumarate
|
TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 |
Proton pump
|
|
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19... |
|
T1651 |
Rabeprazole sodium
|
Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium |
Apoptosis
,
Proton pump
|
|
Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch... |
|
T14389 |
AZD 9272
|
|
GluR
|
|
AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux. |
|
T1756L |
Ilaprazole
|
IY81149,IY 81149,IY-81149 |
Proton pump
,
TOPK
|
|
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm... |
|
T2093 |
PF 03716556
|
PF-3716556 |
ATPase
|
|
PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease. |
|
T0161 |
Pantoprazole Sodium Hydrate
|
SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) |
Apoptosis
,
Potassium Channel
,
Proton pump
,
Autophagy
|
|
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
|
T69984 |
Ticalopride
|
|
5-HT Receptor
|
|
Ticalopride is a 5-HT3 receptor agonist used in the treatment of digestive disorders, orofacial disorders, otorhinolaryngologic disorders, and may be used in the study of bulimia nervosa, gastroesophageal reflux, and irr... |
|
T1291 |
Cisapride
|
Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase |
Potassium Channel
,
5-HT Receptor
,
HER
|
|
Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease... |
|
T6928 |
Pantoprazole
|
SKF96022,BY1023 |
Apoptosis
,
Proton pump
,
Autophagy
|
|
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. |
|
T21385 |
Cinitapride
|
Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove |
5-HT Receptor
|
|
Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag... |
|
T8386 |
Esomeprazole Magnesium trihydrate
|
(S)-Omeprazole magnesium trihydrate |
Proton pump
|
|
Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit... |
|
T10221 |
Abeprazan hydrochloride
|
DWP14012 hydrochloride,Fexuprazan hydrochloride |
Proton pump
|
|
Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat... |
|
T33402 |
Mitemcinal fumarate
|
GM 611,Kita-ku Tokyo,GM-611,Kita-ku Toyko,GM611 |
|
|
Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease. |
|
T27640 |
Itriglumide
|
CR-2945,CR2945,CR 2945 |
|
|
Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD). |
|
T30118 |
Arbaclofen placarbil
|
XP 19986,XP19986,XP-19986 |
|
|
Arbaclofen placarbil( XP19986) is a GABA(B) receptor agonist.Arbaclofen Placarbil is a novel R-baclofen prodrug with improved absorption, distribution, metabolism, and elimination properties compared to R-baclofen. And i... |
|
T68662 |
AZD-3355
|
|
|
|
AZD-3355, also known as Lesogaberan, is a GABA(B)-receptor agonist reflux inhibitor. |
|
T26727 |
Azeloprazole
|
E-3710,Z215,E3710,Z 215,E 3710,Z-215 |
|
|
Azeloprazole, a proton pump inhibitor, is used potentially for the treatment of gastroesophageal reflux disease (GERD). |
|
T31743 |
Famotine hydrochloride
|
Famotine HCl,UK-2054 |
|
|
Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease. |
|
T1552L |
Itopride free base
|
HSR803,HSR-803,Itopride hydrochloride,HSR 803 |
|
|
Itopride HCl is an AChE inhibitor and dopamine D2 receptor antagonist. It inhibits lower esophageal sphincter relaxation. It also used to treat functional dyspepsia and gastroesophageal reflux disease |
|
T16737 |
Revexepride
|
|
Others
|
|
Revexepride is a highly selective agonist of the 5-HT4 receptor and a potential inducer of CYP3A4 enzyme. Revexepride is used for the treatment of gastroesophageal reflux disease. |
|
T16683 |
Pumosetrag Hydrochloride
|
MKC-733,DDP-733 |
5-HT Receptor
|
|
|
|
T19929 |
Ranitidine-S-oxide
|
|
|
|
Ranitidine-S-oxide is a metabolite of Ranitidine. It is commonly used in the treatment of peptic ulcer disease, Zollinger–Ellison syndrome，and gastroesophageal reflux disease. |
|
T70127 |
Famotine
|
|
|
|
Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T71049 |
Famotidine disulfide
|
|
|
|
Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T71485 |
Famotidine propionic acid
|
|
|
|
Famotidine propionic acid is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T71509 |
Famotidine sulfamoyl propanamide
|
|
|
|
Famotidine sulfamoyl propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T68725 |
Famotidine propanamide
|
|
|
|
Famotidine propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T70090 |
Nizatidine amide
|
|
|
|
Nizatidine amide is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
|
T61740 |
Esomeprazole hemistrontium
|
|
|
|
Esomeprazole hemistrontium, also known as (S)-Omeprazole, is a potent and orally active proton pump inhibitor that effectively reduces acid secretion by inhibiting the H+, K+-ATPase in gastric parietal cells. This compou... |
|
T61467 |
Esomeprazole magnesium salt
|
|
|
|
Esomeprazole magnesium salt is a potent and orally active proton pump inhibitor that effectively reduces acid secretion in gastric parietal cells by inhibiting the H+, K+-ATPase. This compound has shown promise for the r... |
|
T68250 |
Omeprazole magnesium
|
|
|
|
Omeprazole magnesium, an orally active proton pump inhibitor (PPI), suppresses gastric acid and is utilized for managing symptoms related to acid reflux and frequent heartburn. |
|
T61667 |
Esomeprazole potassium salt
|
|
|
|
Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is an effective and orally active proton pump inhibitor that works by inhibiting the H+, K+-ATPase enzyme in the gastric parietal cells, leading to a reduction ... |
|
T71980 |
Omeprazole acid
|
|
|
|
Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are... |
|
T31404 |
Dextranomer
|
Dextranomere,Dextranomero,Debrisan,Dextranomerum |
|
|
Dextranomer, for treatment of burns; consists of three-dimensional network of dextran polymers cross-linked by epichlorohydrin; dextranomer based implants usedas a bulking agent for endoscopic treatment of pediatric stru... |
|
T70070 |
Cisapride tartrate
|
|
|
|
Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisa... |
|
T61643 |
Vonoprazan hydrochloride
|
|
|
|
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), effectively acts as a potassium-competitive acid blocker (P-CAB) with potent antisecretory activity. It notably inhibits H+,K+-ATPase activity in porcine gastric m... |
