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Search Results for " sulfhydryl "

ターゲット

33

阻害剤

5

天然化合物

2

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T16251 N-Succinimidyl-S-acetylthioacetate SATA Others
N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecule...
T3088 N-Ethylmaleimide 1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM Cysteine Protease , DUB
N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies.
T19780 2,2′-Dipyridyl disulfide 2,2'-Dipyridyl disulfide,OPSS,Aldrithiol 2,Orthopyridyl disulfide Others
2,2′-Dipyridyl disulfide (Aldrithiol 2) is a useful reagent for the determination of sulfhydryl groups. It acts as a peptide coupling reagent and as an oxidizing agent. 2,2′-Dipyridyl disulfide (Aldrithiol 2) is also use...
T20121 L-Albizziin NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin Glutaminase
L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.
T19955 Biotin-HPDP Pyridyldisulfide-biotin,Pyridyldithiol-biotin Others
Biotin-HPDP (Pyridyldithiol-biotin) is a sulfhydryl reactive biotinylation reagent.
T17389 AMAS Others
AMAS is a non-claevable heterobifunctional crosslinker with NHS ester and maleimide groups that enables covalent conjugation of amine- and sulfhydryl-containing molecules.
T1414 Sodium 2-mercaptoethanesulfonate Mitexan,Uromitexan,Mesna,Mesnum,Mesnex Others
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
T21334 Bucillamine DE-019,Thiobutarit,Tiobutarit,SA96,DE 019,DE019 VEGFR , Antioxidant
Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF. Bucillamine is an orally active sulfhydryl donor and antioxidant with antirheumatic and...
T18728 Sulfo-SMCC sodium Others
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable i...
T5030 Zofenopril calcium SQ26991,Zofenopril (calcium) RAAS , Reactive Oxygen Species
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z...
T1484L Perindopril erbumine S9490-3,Perindopril tert-butylamine salt Apoptosis , RAAS , MRP
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril er...
T6741 SPDP SPDP Crosslinker Others
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ...
T0893 Tinidazole CP12574 Antibacterial , Antibiotic
Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitr...
T1756 Ilaprazole sodium IY-81149 sodium Proton pump , TOPK
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...
T26066 Rev 6134 Rev6134,Rev-6134
Rev 6134 is an ACE-inhibitor with non-sulfhydryl containing.
T19956 Iodoacetyl-LC-Biotin Iaa-Biotin
Iodoacetyl-LC-Biotin reacts with sulfhydryl groups to form stable thioether linkages.
T26065 Rev 5975
Rev 5975 is a non-sulfhydryl ACE-inhibitor.
T26067 Rev 6207 Rev-6207
Rev 6207 is a non-sulfhydryl ACE-inhibitor.
T20758 Trandolaprilat RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403
Trandolaprilat is an inhibitor of non-sulfhydryl angiotensin-converting enzyme.
T71555 Moexipril ethyl ester
Moexipril ethyl ester is a long-acting, non-sulfhydryl angiotensine-converting enzyme inhibitor.
T19568 Sulfo-SMPB sodium Others
Sulfo-SMPB sodium is a non-cleavable heterobifunctional chemical cross-linking reagent that combines N-hydroxysuccinimide ester and maleimide groups. This compound enables the covalent conjugation of molecules possessing...
T21269 Sulfo-EMCS
Sulfo-EMCS is a heterobifunctional sulfhydryl- and amine-reactive crosslinker.
T70884 Moexipril methyl ester
Moexipril methyl ester is a long-acting, non-sulfhydryl angiotensine-converting enzyme inhibitor.
T19942 SBA Crosslinker SBA Cross-linker,SBA Cross linker
SBA crosslinker is a sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents k...
T19437 MTSEA hydrobromide Others
MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain similar in size to lysine.
T19941 MBS Crosslinker MBS protein crosslinker
MBS crosslinker is a non-cleavable, water-insoluble, heterobifunctional protein crosslinking reagent. The MBS protein crosslinker extended spacer arm analog is SMPB crosslinker SATA Protein Modifier can be used to add su...
T19943 SMPB Crosslinker SMPB Cross linker,SMPB Cross-linker
SMPB crosslinker is a heterobifunctional protein crosslinking reagent that is reactive toward sulfhydryl and amino groups. The SMPB protein crosslinker is an extended chain length analog of MBS crosslinker. SMPB crosslin...
T71768 CB10-277
CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alk...
T81904 Lucifer yellow iodoacetamide dipotassium
Lucifer Yellow Iodoacetamide Dipotassium is a thiol-reactive (sulfhydryl-reactive) fluorescent tracer utilized for labeling proteins.
T27974 Maleimide-PEG4-NHS MAL-PEG-NHS,Maleimide PEG NHS,Maleimido-​Tetra(Ethylene Glycol)​-​Acetic Acid NHS ester,MAL-PEG4-NHS
Maleimide-PEG4-NHS is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds formed through Maleimide-PEG4-NHS linker are stable and are not cleavable. The NHS ester reacts with amino groups at ...
T17834 DM4-SPDP Others
DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amin...
T68012 Rebimastat
Rebimastat is a sulfhydryl-based second-generation matrix metalloproteinase (MMP) inhibitor with potential antineoplastic activity. Rebimastat selectively inhibits several MMPs (MMP 1, 2, 8, 9, and 14), thereby inducing ...
T38351 DYn-2
Mild oxidation can convert the sulfhydryl group of cysteine residues on proteins to cysteine-sulfenic acid derivatives (Cys-SOH). Protein sulfenylation, then, is a post-translational modification that is relevant to redo...

Compounds

N-Succinimidyl-S-acetylthioacetate
T16251
Synonym: SATA
Target: Others
N-Ethylmaleimide
T3088
Synonym: 1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM
Target: Cysteine Protease, DUB
2,2′-Dipyridyl disulfide
T19780
Synonym: 2,2'-Dipyridyl disulfide,OPSS,Aldrithiol 2,Orthopyridyl disulfide
Target: Others
L-Albizziin
T20121
Synonym: NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin
Target: Glutaminase
Biotin-HPDP
T19955
Synonym: Pyridyldisulfide-biotin,Pyridyldithiol-biotin
Target: Others
AMAS
T17389
Synonym:
Target: Others
Sodium 2-mercaptoethanesulfonate
T1414
Synonym: Mitexan,Uromitexan,Mesna,Mesnum,Mesnex
Target: Others
Bucillamine
T21334
Synonym: DE-019,Thiobutarit,Tiobutarit,SA96,DE 019,DE019
Target: VEGFR, Antioxidant
Sulfo-SMCC sodium
T18728
Synonym:
Target: Others
Zofenopril calcium
T5030
Synonym: SQ26991,Zofenopril (calcium)
Target: RAAS, Reactive Oxygen Species
Perindopril erbumine
T1484L
Synonym: S9490-3,Perindopril tert-butylamine salt
Target: Apoptosis, RAAS, MRP
SPDP
T6741
Synonym: SPDP Crosslinker
Target: Others
Tinidazole
T0893
Synonym: CP12574
Target: Antibacterial, Antibiotic
Ilaprazole sodium
T1756
Synonym: IY-81149 sodium
Target: Proton pump, TOPK
Rev 6134
T26066
Synonym: Rev6134,Rev-6134
Target:
Iodoacetyl-LC-Biotin
T19956
Synonym: Iaa-Biotin
Target:
Rev 5975
T26065
Synonym:
Target:
Rev 6207
T26067
Synonym: Rev-6207
Target:
Trandolaprilat
T20758
Synonym: RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403
Target:
Moexipril ethyl ester
T71555
Synonym:
Target:
Sulfo-SMPB sodium
T19568
Synonym:
Target: Others
Sulfo-EMCS
T21269
Synonym:
Target:
Moexipril methyl ester
T70884
Synonym:
Target:
SBA Crosslinker
T19942
Synonym: SBA Cross-linker,SBA Cross linker
Target:
MTSEA hydrobromide
T19437
Synonym:
Target: Others
MBS Crosslinker
T19941
Synonym: MBS protein crosslinker
Target:
SMPB Crosslinker
T19943
Synonym: SMPB Cross linker,SMPB Cross-linker
Target:
CB10-277
T71768
Synonym:
Target:
Lucifer yellow iodoacetamide dipotassium
T81904
Synonym:
Target:
Maleimide-PEG4-NHS
T27974
Synonym: MAL-PEG-NHS,Maleimide PEG NHS,Maleimido-​Tetra(Ethylene Glycol)​-​Acetic Acid NHS ester,MAL-PEG4-NHS
Target:
DM4-SPDP
T17834
Synonym:
Target: Others
rebimastat
T68012
Synonym:
Target:
DYn-2
T38351
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
T1630 Tiopronin Thiopronine,Acadione,Captimer ROS
Tiopronin (Acadione), a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.
T1085L Glutathione oxidized Bi(glutathion-S-yl),Oxidized glutathione,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase
Glutathione oxidized (L(-)-Glutathione) is a GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
T15467 Helenalin Others
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine ...
T75671 Senecionine acetate
Senecionine acetate (O-Acetylsenecionine), a pyrrolizidine alkaloid, inhibits the sequestration of Ca2+ in both extramitochondrial and mitochondrial compartments, likely through the inactivation of free sulfhydryl groups...
T10928 Cytochalasin A HIV Protease
Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin polymerization and interferes with microtubu...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-01020 GFER Protein, Human, Recombinant (His) Human E. coli
GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isofo...
TMPJ-00946 TALDO1 Protein, Human, Recombinant (His) Human HEK293 Cells
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway provi...