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T7533 |
Taurolidine
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Apoptosis
,
Others
,
Antibacterial
,
Antibiotic
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Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity. |
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T31668 |
Eribaxaban
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PD 348292,PD0348292,PD-0348292,PD-348292,PD 0348292,PD348292 |
Factor Xa
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Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism. |
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T27920 |
LY 517717
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LY-517717,LY517717 |
Factor Xa
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LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE). |
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T9845 |
Thrombin inhibitor 5
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Thrombin inhibitor 5 (compound 385) is a thrombin inhibitor with IC 50s ranging from 0.1 μM to 1 μM. Thrombin inhibitor 5 can be used for venous thromboembolism research[1]. |
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T0259 |
Chromocarb
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Chromone-2-carboxylic acid,Chromocarbe |
Others
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Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections. |
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T24170 |
Iodoantipyrine
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Jodantipyrine,EINECS 204-966-6,Arthripur,Iodophenazone |
Others
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Iodoantipyrine (Arthripur) is a commonly-used indicator and is used to evaluate in rats by measuring torcular venous efflux after systemic injection of the indicator under conditions of normal and high CBF. |
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T31806 |
Flovagatran
|
TGN 255 |
Thrombin
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Flovagatran (TGN 255) is an orally active, potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism. |
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T29215 |
Zifaxaban
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TY 602,TY602,TY-602 |
Factor Xa
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Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, more than 10,000-fold higher than that of other ser... |
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T0075 |
Nicorandil
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SG-75 |
Potassium Channel
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Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly b... |
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T4341 |
Betrixaban
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PRT054021 |
Factor Xa
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Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel ... |
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T68002 |
Naroparcil
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Thrombin
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Naroparcil, an orally available thioglycoside analog of 4-methylumbelliferyl β-D-xyloside, showed antithrombotic effects in the Wessler sludge model of venous thrombosis (jugular vein).Naroparcil enhanced the formation o... |
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T31206 |
Darexaban
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YM 150,Darexaban, Tanexaban,YM150 |
Factor Xa
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Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati... |
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T0871 |
Noradrenaline bitartrate
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Adrenergic Receptor
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Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors. Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of the ... |
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T1577 |
Midodrine hydrochloride
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Pro-Amatine |
Adrenergic Receptor
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Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This c... |
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T4980 |
Betrixaban maleate
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|
Factor Xa
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Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. |
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T71096 |
GCC-4401C methanesulfonate
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|
|
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GCC-4401C methanesulfonate is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE). |
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T70510 |
CVS-1123
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CVS-1123 is a direct thrombin inhibitor, preventing occlusive arterial and venous thrombosis in a canine model of vascular injury. |
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T11659 |
Inogatran
|
H-314-27 |
Others
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T70681 |
G-4120
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G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis. |
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T71429 |
O-Demethyl apixaban sulfate
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O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases. |
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T70184 |
YM-60828 dihydrochloride
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|
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YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease. |
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T71362 |
GCC-4401C free base
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|
|
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GCC-4401C free base is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE). |
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T64250 |
Desirudin
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|
|
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Desirudin (CGP 39393) is a thrombin inhibitor that inhibits thrombosis and venous stasis thrombosis.Desirudin can be used to study thrombocytopenia or platelet dysfunction associated with thrombocytopenia. |
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T71532 |
Fondaparinux free base
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|
|
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Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is... |
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T68847 |
Aspirin calcium
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Aspirin calcium is the prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition... |
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T70108 |
Fasudil hydrochloride hydrate
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|
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Fasudil hydrochloride hydrate is an HCl salt of Fasudil -- a Rho-kinase (ROCK) inhibitor that has been shown to be effective in hindering the development of mature Cerebral Cavernous Malformation (CCM) lesions as well as... |
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T75408 |
Batroxobin
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|
|
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Batroxobin (DF-521), a venom derived from the Bothrops atrox moojeni snake, facilitates thrombolysis, inhibits thrombus reformation, and offers neuroprotection. It holds research potential for treating cerebral venous th... |
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T0815L |
Warfarin sodium
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|
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An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, an... |
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T70097 |
Acefylline piperazine
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Acefylline piperazine is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. Acephylline piperazine is a theophylline derivative with a direct bronchodilator action. It has the a... |
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T72034 |
LI-2242
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|
Others
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LI-2242 is a potent inositol hexakisphosphate kinase (IP6K) inhibitor with IC50s of 31 nM, 42 nM, 8.7 nM, and 1944 nM for IP6K1, IP6K2, IP6K3, and IPMK, respectively.LI-2242 ameliorated hepatic steatosis by reducing the ... |
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T36427 |
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
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PACAP
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Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expres... |
