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Search Results for " caspase-3 "

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142

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T6005	Z-DEVD-FMK	Caspase-3 Inhibitor	Caspase
	Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.		Caspase
T11696	Ivachtin	Caspase-3 Inhibitor VII	Caspase
	Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining caspases.		Caspase
T21871	MMPSI	Caspase-3/7 Inhibitor I	Apoptosis , Caspase
	MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a ...		Apoptosis , Caspase
T10384	Farudodstat	ASLAN003	Apoptosis , Dehydrogenase , DNA/RNA Synthesis
	Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.		Apoptosis , Dehydrogenase , DNA/RNA Synthesis
T1724	SCR7 pyrazine	SCR7	Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
	SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).		Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
T0300	Pargyline	Pargylamine,Paragyline	MAO , Monoamine Oxidase
	Pargyline (Pargylamine) is a monoamine oxidase inhibitor with antihypertensive properties.		MAO , Monoamine Oxidase
T82774	Caspase-3 activator 3		Caspase
	Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemic activity with IC50 values of 42.89 μM and 33.61 μM, respectively...		Caspase
T6258	Zibotentan	ZD4054	Apoptosis , Endothelin Receptor
	Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.		Apoptosis , Endothelin Receptor
T63479	Caspase-3-IN-1
	Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).
T5104	BTSA1		Apoptosis , BCL
	BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.		Apoptosis , BCL
T8478	SC-43		Apoptosis , Phosphatase , STAT
	SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.		Apoptosis , Phosphatase , STAT
T6993	Tauroursodeoxycholate sodium	Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC)	Apoptosis , ERK , Caspase
	Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.		Apoptosis , ERK , Caspase
T72316	Caspase-3/7 activator 3
	Caspase-3/7 Activator 3 is a potent and tumor-selective compound that effectively activates Caspase-3/7, demonstrating significant anti-proliferative activity and a high capacity to induce apoptosis.
T82775	Caspase-3 activator 2		Caspase
	Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM, respectively [1]. It facilitates apoptosis, rendering it usef...		Caspase
T79743	Caspase-3 activator 1		Pyroptosis
	Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This cleavage enables Caspase-3 to process gasdermin E (GSDME), whic...		Pyroptosis
T1578	Pargyline hydrochloride	Pargylamine hydrochloride	MAO , Monoamine Oxidase
	Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.		MAO , Monoamine Oxidase
T72315	Caspase-3/7 activator 2
	Caspase-3/7 Activator 2 is a potent compound that selectively activates Caspase-3/7, demonstrating tumor specificity, anti-proliferative properties, and a high capacity for inducing apoptosis.
TQ0146L	Ac-DEVD-CHO acetate	Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base)	Caspase
	Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.		Caspase
T38562	AKN-028		FLT
	AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.		FLT
T83963	Z-DEVD-FMK Caspase-3 Inhibitor
	Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and con...
T12412L	PDK4-IN-1 hydrochloride		Apoptosis , PDK
			Apoptosis , PDK
T28178	NLRP3-IN-9	INF-4E,INF 4E,INF4E	NOD
	NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...		NOD
T13416	ZX-29		ALK
	ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect.		ALK
T23861	CAY10526	CAY-10526,BTH,CAY 10526	Prostaglandin Receptor
	CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.		Prostaglandin Receptor
T6085	PF-543	Sphingosine Kinase 1 Inhibitor II,PF 543	Apoptosis , S1P Receptor , Autophagy , LPL Receptor
	PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.		Apoptosis , S1P Receptor , Autophagy , LPL Receptor
T8840	PF-543 hydrochloride	PF-543	Apoptosis , S1P Receptor , Autophagy , LPL Receptor
	PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.		Apoptosis , S1P Receptor , Autophagy , LPL Receptor
T15212	Emamectin Benzoate	MK-244	Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite
	Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
T3340	SCR7		Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
			Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
T10924	Cysteine protease inhibitor-2		Cysteine Protease
	Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.		Cysteine Protease
T9118	KEA1-97		Apoptosis , Others , Caspase
	Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity ...		Apoptosis , Others , Caspase
T15035	Cystamine	2,2'-Disulfanediyldiethanamine	Caspase
	Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used in studies about Huntington's diseases.		Caspase
TQ0146	Ac-DEVD-CHO		Apoptosis , Caspase
			Apoptosis , Caspase
T38563	Raptinal		Caspase
	Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.		Caspase
T7816	Ac-DEVD-pNA		Others
	Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.		Others
T10366L	Arg-Gly-Asp-Ser acetate	Arg-Gly-Asp-Ser acetate(91037-65-9 free base)	Integrin
	Arg-Gly-Asp-Ser acetate is an integrin binding sequence that directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. Arg-Gly-Asp-Ser acetate inhibits integrin ...		Integrin
T7016	VR23		Apoptosis , Proteasome , Caspase
	VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.		Apoptosis , Proteasome , Caspase
T8652	CASP3 Activator 1541		Caspase
	CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.		Caspase
T18909	Ac-DEVD-AMC	AC-ASP-MET-GLN-ASP-AMC,AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN	Caspase
	Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .		Caspase
T1772	MDK83190	Apoptosis Activator 2	Apoptosis , Caspase
	MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .		Apoptosis , Caspase
T19651	Isoflurane	HSDB-8057,Forane,HSDB 8057,HSDB8057,Terrell	Others
	Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.		Others
T8468	CIL62		Caspase
	CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].		Caspase
T26193	SKLB-163	SKLB163	MAPK , Akt , Caspase , Rho , JNK
	SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.		MAPK , Akt , Caspase , Rho , JNK
T61046	Anticancer agent 43		Apoptosis
	Anticancer agent 43 is a potent anticancer agent that induces apoptosis through caspase 3, PARP1, and Bax protein-dependent pathways.Anticancer agent 43 induces DNA damage and can be used in the study of glioblastoma in ...		Apoptosis
T26326	VU0285655-1	VU-0285655,VU0285655,BML 280,VU 0285655,BML280,BML-280	TNF , Phospholipase , Interleukin
	VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhibitory effect on high glucose-induced caspase-3 cleavage and...		TNF , Phospholipase , Interleukin
T9083	TC11	CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11	BCL , Caspase , CDK
	TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.		BCL , Caspase , CDK
T10896L	CSRM617 hydrochloride	CSRM617 hydrochloride(787504-88-5 Free base)	Apoptosis , Others , Androgen Receptor
	CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSR...		Apoptosis , Others , Androgen Receptor
T36819	Ac-FLTD-CMK		Caspase
	Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7...		Caspase
T6275	Obatoclax Mesylate	Obatoclax,GX15-070	BCL , Parasite , Autophagy
	Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.		BCL , Parasite , Autophagy
T22012	7BIO		FLT , DYRK , Aurora Kinase
	7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.		FLT , DYRK , Aurora Kinase
T1933	NVP 231		Apoptosis , ERK
	NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.		Apoptosis , ERK

Compounds

Z-DEVD-FMK

T6005

Synonym: Caspase-3 Inhibitor

Target: Caspase

Ivachtin

T11696

Synonym: Caspase-3 Inhibitor VII

Target: Caspase

MMPSI

T21871

Synonym: Caspase-3/7 Inhibitor I

Target: Apoptosis, Caspase

Farudodstat

T10384

Synonym: ASLAN003

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis

SCR7 pyrazine

T1724

Synonym: SCR7

Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9

Pargyline

T0300

Synonym: Pargylamine,Paragyline

Target: MAO, Monoamine Oxidase

Caspase-3 activator 3

Target: Apoptosis, Endothelin Receptor

Target: Apoptosis, BCL

SC-43

T8478

Synonym:

Target: Apoptosis, Phosphatase, STAT

Tauroursodeoxycholate sodium

T6993

Synonym: Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC)

Target: Apoptosis, ERK, Caspase

Caspase-3/7 activator 3

T72316

Synonym:

Target:

Caspase-3 activator 2

T82775

Synonym:

Target: Caspase

Caspase-3 activator 1

T79743

Synonym:

Target: Pyroptosis

Pargyline hydrochloride

T1578

Synonym: Pargylamine hydrochloride

Target: MAO, Monoamine Oxidase

Caspase-3/7 activator 2

Synonym: Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base)

Z-DEVD-FMK Caspase-3 Inhibitor

T83963

Synonym:

Target:

PDK4-IN-1 hydrochloride

T12412L

Synonym:

Target: Apoptosis, PDK

NLRP3-IN-9

T28178

Synonym: INF-4E,INF 4E,INF4E

Synonym: CAY-10526,BTH,CAY 10526

Target: Prostaglandin Receptor

PF-543

T6085

Synonym: Sphingosine Kinase 1 Inhibitor II,PF 543

Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor

PF-543 hydrochloride

T8840

Synonym: PF-543

Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor

Emamectin Benzoate

T15212

Synonym: MK-244

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite

SCR7

T3340

Synonym:

Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9

Cysteine protease inhibitor-2

T10924

Synonym:

Target: Cysteine Protease

KEA1-97

T9118

Synonym:

Target: Apoptosis, Others, Caspase

Cystamine

T15035

Synonym: 2,2'-Disulfanediyldiethanamine

Target: Apoptosis, Caspase

Arg-Gly-Asp-Ser acetate

T10366L

Synonym: Arg-Gly-Asp-Ser acetate(91037-65-9 free base)

Target: Apoptosis, Proteasome, Caspase

Synonym: AC-ASP-MET-GLN-ASP-AMC,AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN

Target: Caspase

MDK83190

T1772

Synonym: Apoptosis Activator 2

Target: Apoptosis, Caspase

Isoflurane

T19651

Synonym: HSDB-8057,Forane,HSDB 8057,HSDB8057,Terrell

Target: MAPK, Akt, Caspase, Rho, JNK

Synonym: VU-0285655,VU0285655,BML 280,VU 0285655,BML280,BML-280

Target: TNF, Phospholipase, Interleukin

TC11

T9083

Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

Target: BCL, Caspase, CDK

CSRM617 hydrochloride

T10896L

Synonym: CSRM617 hydrochloride(787504-88-5 Free base)

Target: Apoptosis, Others, Androgen Receptor

Synonym: Obatoclax,GX15-070

Target: BCL, Parasite, Autophagy

7BIO

T22012

Synonym:

Target: FLT, DYRK, Aurora Kinase

NVP 231

T1933

Synonym:

Target: Apoptosis, ERK

カタログ番号	製品名	別名	ターゲット
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T21936	M50054		Caspase
	Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.		Caspase
T2S0500	Ilexsaponin A	Ilexsaponin A1	Others
	1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.		Others
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T1079	Metronidazole	Flagyl,Metronidazol,Anagiardil	Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection
	Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T1152	Albendazole	SKF-62979	HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
	Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
T7727	Se-Methylselenocysteine	Se MSC,SeMCys,MSeC,Se-MSC,SeMSC	BCL , IAP , Caspase
	Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.		BCL , IAP , Caspase
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
T3914	Saikosaponin C		Beta Amyloid , Caspase
	Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.		Beta Amyloid , Caspase
T5S2083	Puerarin 6''-O-Xyloside		Apoptosis , Caspase
	Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 an...		Apoptosis , Caspase
T2S0410	Euphorbia factor L1	Euphorbiasteroid	Apoptosis , P-gp
	Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant...		Apoptosis , P-gp
TN1013	Cucurbitacin D		IL Receptor , JNK , STAT
	Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.		IL Receptor , JNK , STAT
T16791	Rottlerin	Mallotoxin,NSC 56346,NSC 94525	CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T3857	Magnolin	(+)-Magnolin	ERK
	Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.		ERK
T5S2283	Sesamolin		p38 MAPK , Caspase , JNK
	1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...		p38 MAPK , Caspase , JNK
T4S1335	Daphnoretin	Dephnoretin,Thymelol	Influenza Virus , Caspase , PKC
	1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...		Influenza Virus , Caspase , PKC
TN1880	Lucidenic acid B	Lucidenicacid B	Apoptosis , Caspase
	Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...		Apoptosis , Caspase
T3S0335	Soyasaponin Bb	Soyasaponin I	NF-κB , Caspase
	1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa...		NF-κB , Caspase
T3771	Methyl protodioscin	Smilax saponin B,NSC-698790	Apoptosis
	Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...		Apoptosis
T3S1227	Aristolactam I	Aristolactam,Aristololactam I,Aristololactum	Apoptosis , Caspase
	1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...		Apoptosis , Caspase
T3240	Citronellol	dihydrogeraniol,(±)-β-Citronellol	Reactive Oxygen Species
	Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.		Reactive Oxygen Species
T75319	Taurodeoxycholic acid	Taurodeoxychloic acid	Apoptosis , Calcium Channel , Caspase
	Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic a...		Apoptosis , Calcium Channel , Caspase
T4085	Paris saponin VII	Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T7452	2-methoxycinnamaldehyde	O-methoxycinnamaldehyde	Apoptosis , Others
	2-methoxycinnamaldehyde is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.		Apoptosis , Others
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
TN1601	Effusol		Caspase
	Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa...		Caspase
T2795	Amygdalin	Laetrile	Others
	Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...		Others
T9113	Myristicin	Myristicine	IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase
	Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ...
T2S2362	Dehydrocorydaline nitrate		BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T2909	Fraxetin	7,8-dihydroxy-6-methoxy coumarin	Apoptosis , Others
	Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a m...		Apoptosis , Others
TN2103	PROCYANIDIN C1		Apoptosis
	Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.		Apoptosis
T2823	Crocin	Gardenia Yellow,Alpha-Crocin	Others
	Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...		Others
T5S1805	5,7-Dihydroxychromone	5,7-Dihydroxy-4H-Chromen-4-One	Others , Virus Protease , PARP , Caspase , Nrf2
	1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...		Others , Virus Protease , PARP , Caspase , Nrf2
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
T4S2326	Cornuside	7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside	ERK , p38 MAPK , NF-κB , JNK
	1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...		ERK , p38 MAPK , NF-κB , JNK
T3S2344	β,β-Dimethylacrylshikonin	Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK , HIF/HIF Prolyl-Hydroxylase
	1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...		ERK , HIF/HIF Prolyl-Hydroxylase
T6S0721	Orientin	Lutexin,Luteolin-8-glucoside	Others
	1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...		Others
T5S1632	Barlerin	8-O-Acetylshanzhiside methyl ester,ND01	VEGFR , TNF , NF-κB , Akt , Caspase
	Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...		VEGFR , TNF , NF-κB , Akt , Caspase
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
T5S0661	Koumine		Others
	1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...		Others
T2698	Asperosaponin VI	Akebia saponin D,Asperosaponin Ⅵ	Apoptosis , Others , Caspase
	Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.		Apoptosis , Others , Caspase
T5S0055	Chelidonine	Helidonine,Khelidonin,Stylophorin	Apoptosis , Others , Influenza Virus
	1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...		Apoptosis , Others , Influenza Virus
TN4087	Furowanin A		Caspase
	Furowanin A shows significant cytotoxicity against HL-60 cells, it induces that Caspase-9 and caspase-3 inhibitors suppresses apoptosis.		Caspase
T27807	13-Methyltetradecanoic acid	LeDSF3
	LeDSF3 is a regulator of the biosynthesis of the antifungal polycyclic tetramate macrolactam HSAF in Lysobacter enzymogenes and anti-tumor agent. LeDSF3 down-regulates p-AKT and activates caspase-3.
TMA0918	Neochamaejasmine A		Caspase
	Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating...		Caspase
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天然物製品

Tauroursodeoxycholate

T2532

Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

Synonym: Ilexsaponin A1

Target: Akt, Caspase, PI3K, STAT, mTOR

Metronidazole

T1079

Synonym: Flagyl,Metronidazol,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

Albendazole

T1152

Synonym: SKF-62979

Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite

Se-Methylselenocysteine

T7727

Synonym: Se MSC,SeMCys,MSeC,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

Dihydrocapsaicin

T2163

Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Target: Others, TRP/TRPV Channel

Saikosaponin C

T3914

Synonym:

Target: Beta Amyloid, Caspase

Puerarin 6''-O-Xyloside

T5S2083

Synonym:

Target: Apoptosis, Caspase

Euphorbia factor L1

T2S0410

Synonym: Euphorbiasteroid

Target: Apoptosis, P-gp

Cucurbitacin D

TN1013

Synonym:

Target: IL Receptor, JNK, STAT

Rottlerin

T16791

Synonym: Mallotoxin,NSC 56346,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

magnolin

T3857

Synonym: (+)-Magnolin

Target: p38 MAPK, Caspase, JNK

Daphnoretin

T4S1335

Synonym: Dephnoretin,Thymelol

Target: Influenza Virus, Caspase, PKC

Lucidenic acid B

TN1880

Synonym: Lucidenicacid B

Target: Apoptosis, Caspase

Soyasaponin Bb

T3S0335

Synonym: Soyasaponin I

Target: NF-κB, Caspase

Methyl protodioscin

T3771

Synonym: Smilax saponin B,NSC-698790

Target: Apoptosis

Aristolactam I

T3S1227

Synonym: Aristolactam,Aristololactam I,Aristololactum

Target: Apoptosis, Caspase

Citronellol

T3240

Synonym: dihydrogeraniol,(±)-β-Citronellol

Target: Reactive Oxygen Species

Taurodeoxycholic acid

T75319

Synonym: Taurodeoxychloic acid

Target: Apoptosis, Calcium Channel, Caspase

Paris saponin VII

T4085

Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

2-methoxycinnamaldehyde

T7452

Synonym: O-methoxycinnamaldehyde

Target: Apoptosis, Others

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Target: IL Receptor, Anti-infection, BCL, P450, PARP, 5-HT Receptor, Caspase, GABA Receptor, NO Synthase

Dehydrocorydaline nitrate

T2S2362

Synonym:

Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Fraxetin

T2909

Synonym: 7,8-dihydroxy-6-methoxy coumarin

Target: Apoptosis, Others

Synonym: Gardenia Yellow,Alpha-Crocin

Target: Others

5,7-Dihydroxychromone

T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

Dehydrocorydaline

T5S2358

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Cornuside

T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

β,β-Dimethylacrylshikonin

T3S2344

Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

Target: ERK, HIF/HIF Prolyl-Hydroxylase

Orientin

T6S0721

Synonym: Lutexin,Luteolin-8-glucoside

Target: Others

Barlerin

T5S1632

Synonym: 8-O-Acetylshanzhiside methyl ester,ND01

Target: VEGFR, TNF, NF-κB, Akt, Caspase

Crocin II

T3779

Synonym: Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

Synonym: Akebia saponin D,Asperosaponin Ⅵ

Target: Apoptosis, Others, Caspase

Chelidonine

T5S0055

Synonym: Helidonine,Khelidonin,Stylophorin

Target: Apoptosis, Others, Influenza Virus

13-Methyltetradecanoic acid

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01056	Caspase-3 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.6 kDa and the accession number is P42574.
TMPY-02831	Caspase-7 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw...
TMPH-01057	Caspase-8 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.9 kDa and the accession number is Q14790.
TMPH-01315	CASR Protein, Human, Recombinant (GST)	Human	E. coli
	CASR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 93.6 kDa and the accession number is P41180.
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPJ-00697	NOL3 Protein, Human, Recombinant (GST)	Human	E. coli
	Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPY-01824	Caspase-14 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses...
TMPJ-00696	NOL3 Protein, Human, Recombinant	Human	E. coli
	Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPJ-00358	DR6 Protein, Mouse, Recombinant (hFc & His)	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may ...
TMPJ-00215	Fas/CD95 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected...
TMPK-00952	CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-00507	UNC5B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-04003	UNC5B Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPJ-00770	Granzyme B/GZMB Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPJ-00483	DFF45 Protein, Human, Recombinant (His)	Human	E. coli
	DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF...
TMPY-04133	UNC5B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPH-02521	PYCARD Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mit...
TMPK-00947	CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00950	CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00948	CDH17 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01224	CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00555	CDH17 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00473	CDH17 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00953	CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00949	CDH17 Domain 7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01223	CDH17 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-06986	FGF-8b Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-00132	Mesothelin Protein, Human, Recombinant	Human	HEK293 Cells
	Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His)	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-04683	CD47 Protein, Human, Recombinant	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-05191	CD47 Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPK-00951	CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00480	NCAM1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-04935	CD47 Protein, Human, Recombinant (aa 1-139, His)	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells)	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi...
TMPY-01180	CD86 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPY-04385	ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ...
TMPY-02640	FAM3B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b...
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc)	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-04273	FGFR2 Protein, Human, Recombinant (aa 1-378, His)	Human	HEK293 Cells
	FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3.
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