Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous histamine.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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50 mg | 在庫あり | ¥ 10,000 | |||
100 mg | 在庫あり | ¥ 13,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous histamine. |
In vitro | In the model of sustained epileptic state induced by picrotoxin, Antazoline can be utilized to protect the intrinsic neural circuitry. |
In vivo | At a concentration of 30 μM, Antazoline effectively reduces neurotoxicity mediated by NMDA and also blocks NMDA-induced currents via a voltage-dependent and rapidly reversible action, with an inhibition rate of 85±3% at a voltage of -60 mV. |
別名 | Phenazocine HCl, Phenazoline hydrochloride, Antazoline HCl |
分子量 | 301.82 |
分子式 | C17H19N3·HCl |
CAS No. | 2508-72-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (149.1 mM)
H2O: 14 mg/mL (46.38 mM)
Ethanol: 4 mg/mL (13.25 mM)
You can also refer to dose conversion for different animals. 詳細
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Antazoline hydrochloride 2508-72-7 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Inhibitor inhibit Antazoline Hydrochloride Phenazoline Hydrochloride Phenazoline Phenazocine HCl Phenazoline hydrochloride Antazoline Antazoline HCl inhibitor