検索結果

Search Results for " proto-oncogene "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T8825	Capmatinib 2HCl.H2O	INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O	c-Met/HGFR
	Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.		c-Met/HGFR
T1963	Capmatinib	NVP-INC280,INC-280,INCB28060	Apoptosis , c-Met/HGFR
	Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.		Apoptosis , c-Met/HGFR
T1962	ASP3026	ASP 3026	Apoptosis , ALK
	ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS.		Apoptosis , ALK
TP2311	C-MYC PEPTIDE EPITOPE TFA		Others
	C-MYC PEPTIDE EPITOPE TFA, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This pe...		Others
T3455	Merestinib	LY2801653	Discoidin Domain Receptor (DDR) , FLT , c-Met/HGFR , ROS , ROS Kinase
	Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosph...
T63790	Cbl-b-IN-3		E1/E2/E3 Enzyme
	Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n...		E1/E2/E3 Enzyme
T31864	FPFS-1169 HCl	R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169
	FPFS-1169 (BPAP-CPD, R-(-)-BPAP, R- FpFS-1169) is a proto-oncogene protein C-Bcl-2 stimulant that is one of the "catecholaminergic and serotonergic enhancers" and may be used for the treatment of Parkinson's disease.
T63359	C-Myc inhibitor 4
	c-Myc inhibitor 4 is a potent, orally active c-Myc-reducing compound. c-Myc is an important proto-oncogene, which is closely associated with the development of many tumors.
T81285	RGB-1
	RGB-1, a polycyclic aromatic hydrocarbon, functions as a stabilizer of RNA G-quadruplexes and may inhibit RNA translation while decreasing NRAS proto-oncogene expression in breast cancer cells [1].
T71187	Foretinib phosphate
	Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vas...
T72201	Pyridostatin hydrochloride	RR82 hydrochloride
	Pyridostatin (RR82) hydrochloride, a G-quadruplex DNA stabilizing agent (Kd = 490 nM), induces replication- and transcription-dependent DNA damage, promoting growth arrest in human cancer cells. It specifically targets t...
T64072	Cbl-b-IN-2
	Cbl-b-IN-2 is an orally active biological compound that inhibits the E3 enzyme Casitas b lineage lymphoma proto-oncogene b (Cbl-b) in the ubiquitin proteasome pathway and can be used in the study of diseases that modulat...

Compounds

Capmatinib 2HCl.H2O

T8825

Synonym: INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O

Target: c-Met/HGFR

Capmatinib

T1963

Synonym: NVP-INC280,INC-280,INCB28060

Target: Apoptosis, c-Met/HGFR

ASP3026

T1962

Synonym: ASP 3026

Target: Apoptosis, ALK

C-MYC PEPTIDE EPITOPE TFA

Target: Discoidin Domain Receptor (DDR), FLT, c-Met/HGFR, ROS, ROS Kinase

Cbl-b-IN-3

T63790

Synonym:

Target: E1/E2/E3 Enzyme

FPFS-1169 HCl

T31864

Synonym: R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169

Pyridostatin hydrochloride

T72201

Synonym: RR82 hydrochloride

カタログ番号	製品名	別名	ターゲット
TQ0165	Arglabin	(+)-Arglabin	NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
	Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.		NOD-like Receptor (NLR) , Transferase , NOD , Autophagy
T5S1103	Isoliensinine	Isoliensinin	Apoptosis , Antioxidant
	1. Isoliensinine (Isoliensinin), a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities. 2. Isoli...		Apoptosis , Antioxidant

天然物製品

Arglabin

TQ0165

Synonym: (+)-Arglabin

Target: NOD-like Receptor (NLR), Transferase, NOD, Autophagy

Isoliensinine

T5S1103

Synonym: Isoliensinin

Target: Apoptosis, Antioxidant

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00548	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103.1 kDa and the accession number is G7MM61.
TMPY-05423	C-MPL Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	C-MPL Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 80.7 kDa and the accession number is A0A1W2Q6N1.
TMPY-01896	HGFR/c-Met Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	HGFR/c-Met Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 102 kDa and the accession number is EDL13881.1.
TMPY-00882	Mer Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	Mer Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 80 kDa and the accession number is Q12866.
TMPY-04330	Mer Protein, Human, Recombinant	Human	HEK293 Cells
	Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.
TMPY-04384	Src Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Src Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is P12931-1.
TMPY-01296	HGFR/c-Met Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is A0A024R759.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPY-00546	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293 Cells
	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128.3 kDa and the accession number is G7MM61.
TMPY-03581	HGFR/c-Met Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	HGFR/c-Met Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128.1 kDa and the accession number is Q2IBC7.
TMPY-04421	FES Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and o...
TMPY-06657	HGFR/c-Met Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	HGFR/c-Met Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 102.53 kDa and the accession number is XP_006236191.1.
TMPY-02068	HGFR/c-Met Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	HGFR/c-Met Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is Q75ZY9.
TMPY-03421	C-MPL Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	C-MPL Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55.1 kDa.
TMPY-00634	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant	Cynomolgus,Rhesus	HEK293 Cells
	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 102.3 kDa and the accession number is G7MM61.
TMPY-06278	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His), Biotinylated	Cynomolgus,Rhesus	HEK293 Cells
	HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103.1 kDa and the accession number is NP_001162100.2.
TMPH-01976	C-Rel Protein, Human, Recombinant (B2M & His)	Human	E. coli
	c-Rel Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPY-04437	Mer Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Mer Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 61.7 kDa and the accession number is Q60805.
TMPY-02291	Mer Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Mer Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79.3 kDa and the accession number is Q60805.
TMPY-04388	BLK Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Blk, also known as B lymphocyte kinase, p55-Blk and BLK, is a member of theprotein kinase superfamily, Tyr protein kinase family and SRC subfamily. BLK / p55-Blk is expressed in lymphatic organ...
TMPH-02791	C-Myc Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPJ-00791	HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpr...
TMPH-01720	C-Myc Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPY-04391	Lyn Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many f...
TMPY-04434	Src Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Src Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 87.7 kDa and the accession number is NP_001020566.111.
TMPH-01721	C-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promotin...
TMPY-06863	C-MPL Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	C-MPL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.64 kDa and the accession number is Q08351-1.
TMPY-01895	HGFR/c-Met Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	HGFR/c-Met Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128 kDa and the accession number is A4FUV6.
TMPY-06797	C-MPL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-MPL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is P40238-1.
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPJ-01143	MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)	Human	HEK293 Cells
	Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPY-03510	Cbl-c Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, C...
TMPY-04363	Mer Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Mer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62 kDa and the accession number is Q12866.
TMPY-04747	Mer Protein, Human, Recombinant (aa 578-872)	Human	Baculovirus Insect Cells
	Mer Protein, Human, Recombinant (aa 578-872) is expressed in Baculovirus insect cells. The predicted molecular weight is 34.1 kDa and the accession number is Q12866.
TMPJ-00647	EGFR vIII Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is NP_001333870.
TMPY-00718	HGFR/c-Met Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 129.5 kDa and the accession number is A0A024R759.
TMPY-05441	HGFR/c-Met Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128.4 kDa and the accession number is A0A024R759.
TMPY-04379	HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST)	Human	Baculovirus Insect Cells
	HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P08581-1.
TMPJ-00648	EGFR vIII Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 61-75 Kda and the accession number is NP_001333870.
TMPY-05095	RAF1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct...
TMPY-05607	HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 104.9 kDa and the accession number is A0A024R759.
TMPJ-00646	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is NP_001333870.
TMPY-02270	RET Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RET Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.1 kDa and the accession number is P07949-1.
TMPY-04418	RET Protein, Human, Recombinant (aa 658-1114, His & GST)	Human	Baculovirus Insect Cells
	RET Protein, Human, Recombinant (aa 658-1114, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.7 kDa and the accession number is P07949-1.
TMPJ-00413	HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860.
TMPJ-00899	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
TMPJ-01418	CSF1R Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ...
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated	Human	HEK293 Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which un...
------------------------ More ------------------------