Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM) which shows synergistic efficacy in combination with targeted alpha therapies. BAY-8400 can be used for the research of cancer [1].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 29,500 | |||
5 mg | 在庫あり | ¥ 60,500 | |||
10 mg | 在庫あり | ¥ 91,500 | |||
25 mg | 在庫あり | ¥ 186,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
100 mg | 在庫あり | ¥ 431,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 66,000 |
説明 | BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM) which shows synergistic efficacy in combination with targeted alpha therapies. BAY-8400 can be used for the research of cancer [1]. |
ターゲット&IC50 | DNA-PK:81 nM |
In vivo | BAY-8400 (150 mg/kg; p.o.) increases the antitumor efficacy that even improved tumor-induced body weight loss. BAY-8400 shows useful aqueous solubility and oral bioavailability across species [1]. |
分子量 | 393.39 |
分子式 | C21H17F2N5O |
CAS No. | T9498 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (152.52 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BAY-8400 T9498 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK BAY 8400 BAY8400 Inhibitor inhibitor inhibit