Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).
ターゲット&IC50 | JAK2:77 nM (cell free), JAK1:17 nM (cell free), TYK2:23 nM (cell free), JAK3:6.9 μM |
別名 | PF-06700841 |
分子量 | 389.4 |
分子式 | C18H21F2N7O |
CAS No. | 1883299-62-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 75 mg/mL (192.60 mM)
DMSO: 75 mg/mL (192.60 mM)
H2O: Insoluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Brepocitinib 1883299-62-4 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells Tyrosine Kinase/Adaptors Tyrosine Kinases JAK inhibit Janus kinase PF-06700841 Inhibitor PF06700841 PF 06700841 inhibitor