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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T11710 | JAK-IN-5 | JAK | |
JAK-IN-5 is a JAK inhibitor. | |||
T13571 | JAK-IN-10 | JAK | |
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders. | |||
T12549 | JAK-IN-11 | R-348 | JAK |
JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment. | |||
T27650 | JAK3i | JAK-3i,JAK 3i | JAK |
JAK3i is a selective covalent inhibitor of JAK3 kinase. JAK3i reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cel... | |||
T61494 | JAK-IN-21 | Tyrosine Kinases , JAK | |
JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively. | |||
T78607 | JAK-STAT-IN-1 | JAK , STAT | |
JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases. | |||
T11710L | JAK-IN-5 hydrochloride | JAK-IN-5 hydrochloride(2096999-92-5 Free base) | JAK |
JAK-IN-5 hydrochloride is a JAK inhibitor [1]. | |||
T3080 | Pyridone 6 | Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I | Tyrosine Kinases , JAK |
Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM... | |||
T39400 | JAK-IN-15 | ||
JAK-IN-15 is a JAK inhibitor. WO2016119700A1 (Compound 15). | |||
T9764 | JAK-IN-14 | ||
JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC 50 of <5 μM. JAK-IN-14 is more than 8-fold selective for JAK1 than JAK2 and JAK3 [1]. | |||
T11705 | JAK-IN-4 | Others | |
JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model. | |||
T11704 | JAK-IN-3 | CCR | |
JAK-IN-3 is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively. | |||
T11703 | JAK-IN-1 | Others | |
T38436 | JAK-2/3-IN-1 | ||
JAK-2/3-IN-1 is a highly effective inhibitor targeting both JAK-2 and JAK-3 isoforms. It exhibits remarkable potency, with Ki values below 250 nM for both isoforms. | |||
T2460 | JAK 3 inhibitor IV | ZM 39923 hydrochloride,Jak3 inhibitor IV | EGFR , Others , JAK |
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase. | |||
T82018 | JAK-IN-33 | JAK | |
JAK-IN-33 (Compound 3 (R)) is a selective inhibitor of the Janus kinase (JAK) family [1]. | |||
T73250 | JAK-IN-17 | ||
JAK-IN-17 is a potent inhibitor of JAK . JAK-IN-17 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases. | |||
T63658 | JAK-IN-18 | ||
JAK-IN-18 is a potent inhibitor of JAK and can be used to study a variety of diseases, particularly eye, skin and respiratory diseases. | |||
T73330 | JAK-IN-24 | ||
JAK-IN-24, a JAK inhibitor, exhibits IC50 values of 0.534 nM and 24 nM in the presence of 4 μM and 1 mM ATP, respectively. Additionally, it effectively inhibits STAT5 phosphorylation induced by PBMC IL-15 with an IC50 of... | |||
T78175 | JAK-IN-25 | JAK | |
JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3. It also demonstrates an IC50 of 28 nM against human whole blood IL-12 (HEB IL-1... | |||
T62556 | JAK-IN-23 | ||
JAK-IN-23 is an orally active dual JAK/STAT and NF-κB inhibitor that inhibits J AK1 (IC50: 8.9 nM), J AK2 (IC50: 15 nM), and J AK3 (IC50: 46.2 nM). JAK-IN-23 exhibits strong anti-inflammatory effects and can reduce the r... | |||
T63026 | JAK-IN-19 | ||
JAK-IN-19 is a potent inhibitor of JAK, with pIC50 values of 7.2 and 7.7 for PBMC IFNγ and HLF Eotaxin, respectively. The pIC50 values for VEGFR2 and Aurora B are 7.0 and 5.8 respectively). | |||
T79882 | JAK-IN-31 | JAK | |
JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2, indicating potent activity across these targets. It is utilized in c... | |||
T79110 | JAK-IN-27 | JAK | |
JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nM for TYK2, 7.7 nM for JAK1, and 629.6 nM for JAK3. Moreover, JA... | |||
T82017 | JAK-IN-34 | JAK | |
JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3, and 1.95 nM for TYK2. It effectively reduces joint swelling w... | |||
T79235 | JAK-IN-30 | JAK | |
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50) values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, an... | |||
TP1269 | Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) | Tyrosine Protein Kinase JAK2 Phospho-Tyr8, 9 | |
Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491. | |||
T79222 | JAK-IN-29 | JAK | |
JAK-IN-29 (Compound 3) is a potent inhibitor of Janus kinases (JAK) [1]. | |||
T79116 | JAK-IN-28 | JAK | |
JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1]. | |||
T63581 | JAK-IN-20 | ||
JAK-IN-20 is a potent, orally active, broad-based JAK inhibitor, capable of acting on JAK1 (IC50: 7 nM), JAK2 (IC50: 5 nM), and JAK3 (IC50: 14 nM).JAK-IN-20 has excellent pharmacokinetic and anti-inflammatory activity in... | |||
T78189 | JAK-IN-26 | JAK | |
JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells wit... | |||
T78708 | JAK/HDAC-IN-2 | JAK | |
JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations. This compound exhibits proapoptotic properties, inhibits histone deace... | |||
T63086 | SYK/JAK-IN-1 | ||
SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2. | |||
T79807 | JAK kinase-IN-1 | JAK | |
JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32 nM, 27 nM, and 3473 nM, respectively [1]. | |||
T60895 | JAK-2/3-IN-3 | ||
JAK-2-/3-IN-3 (compound ST4j) can be used in lymph derived diseases and leukemia research. JAK-2-/3-IN-3 inhibits JAK2 autophosphorylation and induces apoptosis in a time- and dose-dependent manner. JAK-2-/3-IN-3 is a po... | |||
T61323 | JAK-2/3-IN-2 | ||
JAK-2/3-IN-2 (Compound 3h) is a potent dual inhibitor of JAK2 and JAK3. It exhibits inhibitory activity with IC50 values of 23.85 nM and 18.9 nM against JAK2 and JAK3, respectively [1]. | |||
T79768 | HDAC/JAK/BRD4-IN-1 | Epigenetic Reader Domain | |
HDAC/JAK/BRD4-IN-1 (compound 25ap) is a potent triple inhibitor targeting HDAC, JAK, and BRD4. This compound not only inhibits cell proliferation but also induces apoptosis in MDA-MB-231 cells and demonstrates in vivo an... | |||
T5492 | JAK3-IN-6 | JAK | |
JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM | |||
T38624 | Fosifidancitinib | JAK | |
Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3. | |||
T10009 | JAK3-IN-7 | JAK | |
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after organ transplantation, autoimmune disorders, allergic diseases, ... | |||
T35899 | JAK1-IN-8 | JAK1-IN-8 | JAK |
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM). | |||
T35900 | JAK2-IN-7 | JAK2-IN-7 | JAK |
JAK2-IN-7, a selective inhibitor targeting Janus Kinase 2 (JAK2), exhibits inhibitory concentrations (IC50) of 3 nM for JAK2, 11.7 nM for SET-2 cells, and 41 nM for Ba/F3 V617F cells, indicative of its potency and select... | |||
T40443 | JAK2-IN-6 | JAK2-IN-6 | JAK |
JAK2-IN-6, a polysubstituted aminothiazole derivative, is a potent and selective inhibitor of JAK2 (ic50 at 22.86 μg/mL). Jak2-in-6 inhibits the activity of JAK2 enzymes by interfering with Jak2-related signaling pathway... | |||
T3069 | AZD-1480 | JAK | |
AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies... | |||
T11706 | Londamocitinib | AZD4604 | JAK |
Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity. | |||
T6790 | BMS-911543 | BMS911543 | Tyrosine Kinases , Histone Methyltransferase , JAK |
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2. | |||
T4210 | SAR-20347 | SAR20347 | Tyrosine Kinases , JAK |
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM). | |||
T5091 | FM-381 | FM381 | JAK |
FM381 is a potent covalent reversible inhibitor of JAK3. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively. | |||
T2156 | WP1066 | Apoptosis , JAK , STAT | |
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra... | |||
T6122 | CEP-33779 | CEP33779 | JAK |
CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4672 | Brevilin A | Apoptosis , Anti-infection , JAK , STAT , Autophagy | |
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si... | |||
TJS1779 | Protosappanin A | PTA | NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT |
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ... | |||
T6S1966 | Curculigoside | Curculigoside A | Antioxidant , NF-κB , JAK , STAT |
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord... | |||
T5S0167 | Atractylenolide I | IL Receptor , TNF , TLR , JAK , STAT | |
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide... | |||
TQ0196 | Cucurbitacin I | NSC-521777,JSI-124,Elatericin B | JAK , STAT |
Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity. | |||
T4S1499 | Ginsenoside Rk1 | Apoptosis , Others , NF-κB , PI3K , JAK | |
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. It also h... | |||
T16324 | Nimbolide | Apoptosis , NF-κB , CDK | |
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene ... | |||
TN1567 | Delphinidin chloride | Estrogen Receptor/ERR , VEGFR | |
Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in va... | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
T5S1897 | Linderalactone | Apoptosis , Others , JAK | |
1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL. | |||
T6S1141 | Ganoderic acid A | Apoptosis , NF-κB , Endogenous Metabolite , Autophagy | |
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a... | |||
T19934 | Dehydrocrenatidine | TOP 3,TOP-3,O-Methylpicrasidine I,TOP3,Kumujian G | Apoptosis , JAK |
Dehydrocrenatidine (Kumujian G) is an inhibitor of JAK and induces cell apoptosis. | |||
TN4774 | Physalin A | ERK , BCL , p38 MAPK , NF-κB , Androgen Receptor , ROS , JAK , JNK , STAT , p53 , Autophagy | |
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and dow... | |||
TN3364 | Agrimonolide | Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK | |
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-02273 | JAK1 Protein, Human, Recombinant (His) | Human | Yeast |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ... | |||
TMPH-02272 | JAK1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ... | |||
TMPH-02961 | JAK1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ... | |||
TMPH-02274 | JAK2 Protein, Human, Recombinant (His) | Human | E. coli |
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto... | |||
TMPK-00474 | IL-22RA1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component o... | |||
TMPJ-00059 | IL-7 Protein, Human, Recombinant (His) | Human | Human Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions... | |||
TMPY-02647 | IFNAR1 Protein, Human, Recombinant (His) | Human | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPY-03532 | LIF Protein, Human, Recombinant (His) | Human | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-04632 | IL-15 Protein, Human, Recombinant | Human | E. coli |
The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common h... | |||
TMPY-05274 | IL-23R Protein, Human, Recombinant (His) | Human | HEK293 |
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo... | |||
TMPY-00136 | IL-29 Protein, Human, Recombinant | Human | HEK293 |
Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL... | |||
TMPY-04104 | LIF Protein, Human, Recombinant | Human | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-04278 | LIF Protein, Mouse, Recombinant | Mouse | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-01701 | IL-12RB1 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 12 receptor, beta 1 is also known as IL-12 receptor beta component, IL-12R subunit beta-1, and CD212 antigen (CD212). IL12RB1(CD212) is a subunit of the interleukin 12 receptor. IL12RB1(CD212) is a type I tra... | |||
TMPY-05242 | CRLF2/TSLPR Protein, Human, Recombinant (His) | Human | HEK293 |
Overexpression of cytokine receptor-like factor 2 (CRLF2) due to chromosomal rearrangement has been observed in acute lymphoblastic leukemia (ALL) and reported to contribute to oncogenesis and unfavorable outcome in ALL.... | |||
TMPY-01872 | IL-28B Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda... | |||
TMPY-01053 | Prolactin Receptor Protein, Human, Recombinant (His) | Human | HEK293 |
Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept... | |||
TMPY-05748 | CD45 Protein, Human, Recombinant (aa 26-577, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05308 | CD45 Protein, Human, Recombinant (aa 1-529, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05480 | IL-21R Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil... | |||
TMPY-00418 | IL-21R Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil... | |||
TMPY-01934 | IL-21R Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R, and NILR, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 4 subfamil... | |||
TMPY-01845 | IL-10 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-05064 | IL-10 Protein, Mouse, Recombinant | Mouse | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-03547 | IL-10 Protein, Human, Recombinant | Human | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-01410 | IL-3R alpha/CD123 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf... | |||
TMPY-03644 | CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-03776 | CD25/IL2R alpha Protein, Cynomolgus, Recombinant | Cynomolgus | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-01103 | CD25/IL2R alpha Protein, Human, Recombinant (His) | Human | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-05584 | CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-05090 | CD25/IL2R alpha Protein, Rat, Recombinant (His) | Rat | Baculovirus-Insect Cells |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-01923 | CD25/IL2R alpha Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-05644 | CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated | Rhesus | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPK-00343 | IFNAR1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-00326 | IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-01071 | IL-22RA1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ... | |||
TMPK-00342 | IFNAR1 Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-00325 | IFNAR1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-01105 | IL-22RA1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ... | |||
TMPU-00003 | STAT2 Protein, Human, Recombinant (His) | Human | E. coli |
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading... | |||
TMPK-00353 | IL-23R Protein, Human, Recombinant (aa 24-355, His) | Human | HEK293 |
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex cons... | |||
TMPK-00575 | IL-23R Protein, Canine, Recombinant (His) | Canine | HEK293 |
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex cons... | |||
TMPH-00779 | IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc) | Guinea pig | E. coli |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 b... | |||
TMPJ-00076 | IL-28B Protein, Human, Recombinant | Human | Human Cells |
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to pla... | |||
TMPK-01094 | IL-23R Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex cons... | |||
TMPK-00652 | IL-23R Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex cons... | |||
TMPJ-00326 | CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated | Human | Human Cells |
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 recepto... | |||
TMPY-03829 | IFNAR1 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPY-01489 | IFNAR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPH-02456 | IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc) | Mesocricetus auratus | E. coli |
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.; Associates with IL23A... | |||
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