SB2 | TargetMol

カタログ番号	製品名	別名	ターゲット
T23861	CAY10526	CAY-10526,BTH,CAY 10526	Prostaglandin Receptor
	CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.		Prostaglandin Receptor
T12851	SB290157 trifluoroacetate		Complement System
	SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).		Complement System
T1955	SB225002		CXCR
	SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.		CXCR
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
T16856	SB228357		5-HT Receptor
	SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.		5-HT Receptor
T6657	SB273005		Integrin
	SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.		Integrin
T75013	SB26019
	SB26019 is a potent anti-neuroinflammatory compound that modulates the activation of NF-κB by promoting the formation of monomeric α-tubulin. This action of SB26019, in turn, hinders the translocation of p65, signifying ...
T16857	SB269652		Others
	SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor.		Others
T28681	SB220025	SB-220025,SB 220025
	SB220025, a specific and potent inhibitor of human p38 mitogen-activated protein kinase, reduces the production of tumor necrosis factor induced by lipopolysaccharide.
T28688	SB2602	SB-2602,SB 2602
	SB2602 selectively inhibits mTOR.
T82961	ASB20123
	ASB20123, a CNP/ghrelin chimeric peptide, promotes bone growth and has potential research applications in growth disorders and dwarfism [1].
T28685	SB236057	SB-236057,SB 236057
	SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a pote...
T28683	SB234551	SB 234551,SB-234551
	SB234551 is a selective antagonist of endothelin ETA receptor.
T28687	SB251023	SB-251023,SB 251023
	SB251023 is an agonist of β3-adrenoceptor.

Compounds

CAY10526

T23861

Synonym: CAY-10526,BTH,CAY 10526

Target: Prostaglandin Receptor

SB290157 trifluoroacetate

T12851

Synonym:

Target: Complement System

Target: 5-HT Receptor

Synonym: SB-220025,SB 220025

Target:

SB2602

T28688

Synonym: SB-2602,SB 2602

Synonym: SB-236057,SB 236057

Target:

SB234551

T28683

Synonym: SB 234551,SB-234551

Target:

SB251023

T28687

Synonym: SB-251023,SB 251023

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02257	TPSB2 Protein, Human, Recombinant (His & Myc)	Human	P. pastoris (Yeast)
	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (Hi...
TMPH-02258	TPSB2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. TPSB2 Protein, Human, Recombinant (E....
TMPJ-00542	TPSB2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites faci...
TMPJ-00897	TPSB2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled...