Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 9,000 | |||
50 mg | 在庫あり | ¥ 10,500 | |||
100 mg | 在庫あり | ¥ 13,000 | |||
200 mg | 在庫あり | ¥ 18,500 | |||
500 mg | 在庫あり | ¥ 30,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
説明 | CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity. |
In vitro | CB-103 has shown the ability to block NOTCH signaling in human T cell acute lymphoblastic leukemia cancer cell lines, and exhibits anti-tumor efficacy in GSI resistant T-ALL cell lines[2]. |
In vivo | CB-103inhibits growth of GSI/Mab resistant triple negative breast cancer, andexhibits anti-tumor activity in xenograft models of human T-ALL and mouse mammary tumors[3]. |
分子量 | 242.32 |
分子式 | C15H18N2O |
CAS No. | 218457-67-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (206.34 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CB-103 218457-67-1 Neuroscience Proteases/Proteasome Stem Cells Gamma-secretase CB 103 pathway CB103 inhibit Inhibitor Notch signaling leukemia inhibitor