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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T13345 | Wnt pathway activator 2 | Others , Wnt/beta-catenin | |
Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM. | |||
T17256 | Wnt pathway activator 1 | Wnt/beta-catenin | |
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM. Wnt pathway activator 1 is a potent Wnt activator for the treatment of androgenetic alopecia (AGA). | |||
T77502 | Wnt pathway inhibitor 3 | Wnt/beta-catenin , Adenylyl cyclase | |
Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies to ameliorate osteoarthritis in a mouse model of experimenta... | |||
T77716 | Wnt pathway inhibitor 4 | Antibacterial | |
Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells. | |||
T3156 | Ciliobrevin A | Hedgehog Pathway Inhibitor 4,HPI-4 | Hedgehog/Smoothened |
Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM. | |||
T38519 | YB-0158 | Wnt pathway inhibitor 2,YB-0158 | |
YB-0158 (Wnt pathway inhibitor 2) is a powerful peptidomimetic compound that effectively targets colorectal cancer stem cells (CSCs) by disrupting the interaction between Sam68 and Src proteins. This compound acts as a r... | |||
T25502 | HIF-IN-33 | HIF IN 33,HIF Pathway Inhibitor 33 | |
HIF-IN-33 is an inhibitor of HIF pathway. | |||
T12246 | CB-103 | Gamma-secretase | |
CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity. | |||
T9810 | TNIK-IN-5 | Wnt/beta-catenin | |
TNIK-IN-5 is an potent TNIK inhibitor (IC50= 0.05 μM). TNIK-IN-5 potently inhibits Wnt signaling in intact cells. TNIK-IN-5 exhibits excellent in vitro anti-colorectal cancer activity. | |||
T12885 | SGC-AAK1-1 | AAK1 (AP2 associated kinase 1) | |
SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe. | |||
T9165 | AZD5305 | PARP | |
AZD5305 is a potent, selective and oral active PARP inhibitor. | |||
T5210 | BAI1 | Apoptosis , BCL | |
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM). | |||
T19857 | Glyphosate | Atila,Lancer,Folusen | Apoptosis , Autophagy |
Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans. | |||
T41286 | N6-Isopentenyladenosine | Endogenous Metabolite , Autophagy | |
N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different... | |||
T5486 | RU.521 | RU320521 | DNA , cGAS |
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS. | |||
T5465 | PF-5274857 | PF-5274857 freebase | Smo |
PF-5274857 (PF-5274857 free base) is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor t... | |||
T14327 | AS1949490 | Phosphatase | |
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM. | |||
T20723 | LGE-899 | Sonidegib metabolite M48,LGE 899 | Drug Metabolite |
LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib. | |||
T22665 | PD 128042 | CI 976 | Acyltransferase |
PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multi... | |||
T9189 | Iptacopan hydrochloride | Iptacopan HCl,LNP023 hydrochloride | Complement System |
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b... | |||
T7739 | L-Leucyl-L-Leucine methyl ester hydrochloride | Leu-Leu-ome hydrochloride | Others , Endogenous Metabolite |
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes. | |||
T1967 | AZD-3463 | ALK/IGF1R inhibitor | Apoptosis , IGF-1R , ALK , Autophagy |
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency. | |||
T1487 | Fluvastatin sodium | XU 62320 sodium,XU-62-320,Fluvastatin sodium salt | Ferroptosis , HMG-CoA Reductase , Autophagy |
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent. | |||
T9105 | NF-κB-IN-1 | 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)- | IκB/IKK , NF-κB |
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir... | |||
T6146 | Dorsomorphin dihydrochloride | BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride | AMPK , Autophagy , TGF-beta/Smad |
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases. | |||
T8851 | I3MT-3 | HMPSNE | Hippo pathway |
I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST... | |||
T60055 | Chromeceptin | 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile | Akt , IGF-1R , mTOR |
Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway. | |||
T24784 | SF5 | SF-5,SF 5 | Apoptosis |
SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade. | |||
T67866 | YW2036 | Wnt/beta-catenin | |
YW2036 is an inhibitor of Wnt signaling pathway. | |||
T20759 | XRP44X | XRP-44-X,XRP 44X,XRP-44X,XRP 44 X | Ras |
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway. | |||
T4609 | Exo1 | Others | |
Exo1 is an inhibitor of the exocytic pathway | |||
T6165 | Bardoxolone Methyl | RTA 402,CDDO Methyl ester,TP-155,NSC 713200 | Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy |
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities. | |||
T3588 | JK184 | Hedgehog/Smoothened | |
JK184 is a potent Hedgehog (Hh) pathway inhibitor. | |||
T2273 | ITD-1 | TGF-beta/Smad | |
ITD-1 is a potent and highly selective TGFβ pathway inhibitor. | |||
T64388 | 3-Phenoxybenzaldehyde | Complement System | |
3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM. | |||
T1806 | IDO-IN-7 | NLG919,Navoximod,NLG-919 analogue,GDC-0919 | Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor. | |||
T37538 | Amifostine thiol | ||
Amifostine thiol (WR-1065), the active metabolite of cytoprotector Amifostine, serves as a cytoprotective agent possessing radioprotective properties. It activates p53 via a JNK-dependent signaling pathway[1][2][3]. | |||
T24642 | YH-306 | YH306,TRV055 acetate (25849-90-5 Free base) | MMP , MMP , FAK , Rho , PI3K , Src |
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis. | |||
T50107 | Ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate | Others | |
ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ... | |||
T60038 | 5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole | Others | |
5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole can be used in the synthesis of heterocyclic compounds to inhibit HIF pathway activity. | |||
T23861 | CAY10526 | CAY-10526,BTH,CAY 10526 | Prostaglandin Receptor |
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway. | |||
T3169 | KC7F2 | HIF/HIF Prolyl-Hydroxylase , HIF | |
KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity. | |||
T77780 | Zamaporvint | RXC004 | Others |
Zamaporvint (RXC004) is a selective, orally active and potent inhibitor of the Wnt pathway that acts on the membrane-bound fatty acyltransferase porcupine to block Wnt ligand palmitoylation, secretion, and pathway activa... | |||
T0459 | Sulindac | Arthrocine,MK-231,Clinoril,Sulindac sulfoxide | COX , Autophagy |
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl... | |||
T8917 | PAR-2-IN-1 | IUN76750 | Protease-activated Receptor |
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects. | |||
T2651 | IWR-1 | IWR-1-endo,endo-IWR 1 | Wnt/beta-catenin |
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM). | |||
TQ0071 | Navoximod | GDC-0919,NLG-919 | Indoleamine 2,3-Dioxygenase (IDO) |
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM). | |||
T67732 | Potassium trimethylsilanolate | Trimethylsiloxypotassium | Others |
Potassium trimethylsilanolate is a catalyst. Potassium trimethylsilanolate promotes the Suzuki-Miyaura reaction by (TMSOK) proceeds through the boronate pathway. | |||
T38563 | Raptinal | Caspase | |
Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines. | |||
T37422L | Ras Inhibitory Peptide acetate | Ras Inhibitory Peptide acetate(159088-48-9 Free base) | Ras |
Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic receptors. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4766 | 3-Methylglutaric acid | Endogenous Metabolite | |
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als... | |||
T3912 | Saikosaponin B1 | Others | |
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro. | |||
TN1019 | Beta-mangostin | β-Mangostin | Apoptosis , Antibacterial , Parasite |
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo... | |||
TN6339 | (R)-5-Hydroxy-1,7-diphenylheptan-3-one | (5R)-Dihydroyashabushiketol | Others |
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop... | |||
TN6714 | Geranylgeraniol | FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095 | Apoptosis |
Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ... | |||
TN6739 | Angoline | 6-Methoxyldihydrochelerythrine | IL Receptor , STAT |
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can... | |||
TQ0190 | D-Xylulose | Others , Endogenous Metabolite | |
D-Xylulose is converted from xylitol by the enzyme NAD+-linked xylitol dehydrogenase in the glucuronate pathway, the most important xylitol-handling metabolic pathway in mammals. | |||
T5253 | 3-Methyladipic acid | Others , Endogenous Metabolite | |
3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabo... | |||
T4941 | D-Fructose-6-phosphate disodium salt | D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT | Others , Endogenous Metabolite |
D-Fructose-6-phosphate disodium salt (D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT) is an important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step ... | |||
T19121 | 3-Hydroxyvaleric acid | Endogenous Metabolite | |
3-Hydroxyvaleric acid participates in the complementary pathway of the tricarboxylic acid cycle. | |||
T4901 | 5'-Guanylic acid disodium salt | Guanosine 5'-monophosphate disodium salt,GMP-5 | Others , Endogenous Metabolite |
5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy... | |||
T8281 | (R)-Sulforaphane | L-Sulforaphane | Nrf2 |
(R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway. | |||
TJS1779 | Protosappanin A | PTA | NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT |
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ... | |||
TN1271 | Scutellarein tetramethyl ether | 4',5,6,7-Tetramethoxyflavone | PAFR |
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is extracted from Siam weeds and exhibits anti-inflammatory activity through NF-κB pathway. | |||
T3S1227 | Aristolactam I | Aristolactam,Aristololactam I,Aristololactum | Apoptosis , Caspase |
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF... | |||
TN2237 | Steviol-19-O-glucoside | Steviol-19-O-Glucoside | Others |
Steviol-19-O-glucoside is a natural product from the steviol glycosides biosynthesis pathway in Stevia rebuadiana. | |||
T19343L | Glycerol 3-phosphate biscyclohexylammonium salt | Endogenous Metabolite | |
Glycerol 3-phosphate biscyclohexylammonium salt is an endogenous metabolite produced by cytosolic glycerol 3-phosphate dehydrogenase pathway. | |||
TN1786 | Isomerazin | Isomeranzin | ERK , NF-κB , AChE |
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway. | |||
T2995 | Chrysophanol | 3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb | EGFR |
Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel. | |||
T3386 | Kaempferitrin | Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside | cell cycle arrest , Glucokinase , IGF-1R |
Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos... | |||
T20255 | L-Galactose | Galactose, L- | Endogenous Metabolite |
L-Galactose (Galactose, L-) is a natural product that is widely found in plants and animals. L-Galactose has been shown to be a key intermediate in the molecular pathway for the conversion of D-glucose to oxalic acid in ... | |||
T19343 | Sn-Glycerol 3-phosphate | Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt | Endogenous Metabolite |
sn-Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway. | |||
T8092 | Taurohyodeoxycholic acid sodium salt | Sodium taurohyodeoxycholate hydrate | Caspase |
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. | |||
T2O2776 | L-Valine | Others , Endogenous Metabolite | |
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway. | |||
T8200 | Ginkgolide K | AMPK , Autophagy | |
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity. | |||
TN1058 | Pelargonidin chloride | NOS , Reactive Oxygen Species , Nrf2 , NO Synthase | |
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. | |||
T6S1367 | Procyanidin B2 | Proanthocyanidin B2 | Reactive Oxygen Species , NOD |
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ... | |||
T7468 | (-)-α-Terpineol | α-Terpineol | Others |
(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway | |||
TN1836 | Kudinoside D | LDL , AMPK , PPAR | |
Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway. | |||
T4S0290 | Araloside A | Chikusetsusaponin IV | RAAS , Fas/FasL |
Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway. | |||
TN1684 | Ginsenoside F5 | Apoptosis | |
Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway | |||
TN2232 | Soyasaponin Ab | NOS , NF-κB , COX | |
Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab. | |||
TN6771 | Malabaricone B | Others | |
Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway. | |||
T5793 | Britannin | Apoptosis , AMPK , Autophagy | |
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells. | |||
T2845 | Imperatorin | Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen | TRP/TRPV Channel , AChR , AChE , NOD |
Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo. | |||
T6S0107 | Peimine | Wanpeinine A,Dihydroisoimperialine,Verticine | Others |
1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway. | |||
T7210 | Guanosine 5'-diphosphate | GDP | Endogenous Metabolite |
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. | |||
TN1833 | Karacoline | NF-κB | |
Karacolinem is a natural product, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway. | |||
T4672 | Brevilin A | Apoptosis , Anti-infection , JAK , STAT , Autophagy | |
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si... | |||
T40646 | Lipoteichoic acid | Complement System | |
Lipoteichoic acid, a polymer of Staphylococcus aureus cell wall, activates the complement system by inducing C3 and inhibiting CD55, and reduces fat deposition via the IGF-1 pathway. | |||
T7033 | Rosmanol | Antioxidant , COX | |
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a... | |||
T3871 | Daucosterol | Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A | Glucosidase |
Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1... | |||
T5S0658 | Corynoxine | Autophagy | |
Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla. It is an autophagy enhancer that promotes α-synuclein clearance through the Akt/mTOR pathway. | |||
T13803 | N-Oleoyl glycine | Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR | |
N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte | |||
T4912 | Jatrorrhizine chloride | Yatrorhizine chloride,Neprotine chloride | Others , 5-HT Receptor , OCT , Antibacterial , AChE |
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h... | |||
T3S2344 | β,β-Dimethylacrylshikonin | Dimethylacrylshikonin,β, β-Dimethylacrylshikonin | ERK , HIF/HIF Prolyl-Hydroxylase |
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant... | |||
T5S0331 | Isoliquiritin | Neoisoliquritin | p53 , Antifungal |
1. Isoliquiritin (Neoisoliquritin) has antitussive effects. 2. Isoliquiritin has antidepressant-like effects. 3. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk betwee... | |||
T2140 | Parthenolide | (-)-Parthenolide | Apoptosis , Mitophagy , NF-κB , HDAC , Autophagy |
(-)-Parthenolide ((-)-Parthenolide), an inhibitor of the Nuclear Factor-κB Pathway, also promotes the ubiquitination of MDM2 and activates p53 cellular functions. | |||
T2739 | Shikimic Acid | Shikimate | Others , Endogenous Metabolite |
Shikimic Acid (Shikimate) is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it. | |||
T4096 | Quinolinic acid | pyridine-2,3-dicarboxylic acid,QUIN | Endogenous Metabolite , NMDAR , iGluR |
Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-01174 | DKK1 Protein, Rhesus, Recombinant (N256Q, His) | Rhesus | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-04811 | DKK1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-00775 | DKK1 Protein, Human, Recombinant (His) | Human | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-01121 | DKK3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p... | |||
TMPY-01030 | TFPI Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-01175 | DKK1 Protein, Rhesus, Recombinant (N256Q, mFc) | Rhesus | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-05797 | DKK1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-06377 | DKK3 Protein, Human, Recombinant | Human | HEK293 |
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p... | |||
TMPY-02859 | TFPI2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei... | |||
TMPY-05479 | DKK1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-00950 | WISP1/CCN4 Protein, Human, Recombinant (His) | Human | HEK293 |
CCN4/Wnt-induced secreted protein 1 (WISP1) is a secreted, cysteine-rich, heparin-binding glycoprotein, belonging to the CCN (CTGF/CYR61/NOV) family of growth factors, and is involved in diverse biological functions such... | |||
TMPY-02329 | TFPI2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei... | |||
TMPY-01004 | TFPI2 Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei... | |||
TMPY-05179 | TFPI Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-00928 | TFPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-03626 | R-Spondin 1/RSPO1 Protein, Human, Recombinant | Human | CHO |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-03197 | R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His) | Mouse | CHO |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-01147 | R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) | Human | HEK293 |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-05081 | Notch 1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair... | |||
TMPY-00680 | BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) | Human,Mouse,Rat,Rhesus,Canine | HEK293 |
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin... | |||
TMPY-06418 | R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. Activator of the beta-catenin signaling cascade leads to TCF-dependent gene... | |||
TMPY-01429 | RELT/TNFRSF19L Protein, Human, Recombinant (His) | Human | HEK293 |
Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in he... | |||
TMPY-02028 | RON/CD136 Protein, Human, Recombinant (His) | Human | HEK293 |
The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ... | |||
TMPY-04874 | IL-23 P19/IL23A Protein, Human, Recombinant (hFc) | Human | HEK293 |
IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35. IL-23 is a heterodimeric cytokine, comprised of a unique p19 subunit and p4 subunit, t... | |||
TMPY-02879 | IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) | Human | E. coli |
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a... | |||
TMPY-04153 | RNF43 Protein, Human, Recombinant (His) | Human | HEK293 |
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr... | |||
TMPY-00686 | Complement C2 Protein, Human, Recombinant (His) | Human | HEK293 |
Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in ext... | |||
TMPY-02481 | ACOX1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ... | |||
TMPY-01101 | Coagulation factor X/F10 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the... | |||
TMPY-01081 | SR-BI/SCARB1 Protein, Human, Recombinant (His) | Human | HEK293 |
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz... | |||
TMPY-05435 | ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPY-04830 | GAS6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ... | |||
TMPY-05156 | ICOS Protein, Human, Recombinant (rFc) | Human | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-02473 | ICOS Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-05242 | CRLF2/TSLPR Protein, Human, Recombinant (His) | Human | HEK293 |
Overexpression of cytokine receptor-like factor 2 (CRLF2) due to chromosomal rearrangement has been observed in acute lymphoblastic leukemia (ALL) and reported to contribute to oncogenesis and unfavorable outcome in ALL.... | |||
TMPY-02279 | Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) | Human | E. coli |
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en... | |||
TMPK-00369 | HGF Protein, Human, Recombinant (hFc) | Human | HEK293 |
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different i... | |||
TMPY-03565 | Mannan Binding Lectin/MBL2 Protein, Human, Recombinant | Human | CHO |
MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein, which binds sugar structures on micro-organisms and dying host cells and is one of the four known mediators that initiate activation ... | |||
TMPY-00392 | PAM Protein, Human, Recombinant (His) | Human | HEK293 |
Peptidylglycine alpha-amidating monooxygenase (PAM) is highly expressed in neurons and endocrine cells, where it catalyzes one of the final steps in the biosynthesis of bioactive peptides. PAM is also expressed in unicel... | |||
TMPY-01084 | TrkA Protein, Human, Recombinant (His) | Human | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-01750 | HVEM Protein, Human, Recombinant (His) | Human | HEK293 |
Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup... | |||
TMPY-02361 | VEGFR2/KDR Protein, Human, Recombinant (His) | Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ... | |||
TMPY-01725 | Leptin Receptor Protein, Human, Recombinant (His) | Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe... | |||
TMPY-00949 | VEGFR3/FLT4 Protein, Human, Recombinant (His) | Human | HEK293 |
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo... | |||
TMPY-02333 | ULBP-2 Protein, Human, Recombinant (His) | Human | HEK293 |
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e... | |||
TMPY-01281 | ACVR2B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ... | |||
TMPY-06842 | BMP-4 Protein, Human, Recombinant (E399D) | Human | E. coli |
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP... | |||
TMPY-01936 | VEGFR3/FLT4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo... | |||
TMPY-00654 | ACVR2B Protein, Human, Recombinant (hFc) | Human | HEK293 |
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ... | |||
TMPY-05592 | ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated | Human | HEK293 |
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e... | |||
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L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; | |||
L1310 | Cytoskeletal Signaling Pathway Compound Library | 759 compounds | |
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS; | |||
L4300 | Wnt/Hedgehog/Notch Compound Library | 237 compounds | |
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; | |||
L2521 | Glycolysis Compound Library | 555 compounds | |
555 glycolysis-related active compounds for high-throughput and high-content screening. | |||
L1300 | PI3K-AKT-mTOR Compound Library | 420 compounds | |
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; | |||
L3700 | JAK-STAT Compound Library | 252 compounds | |
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening; | |||
L8700 | Ferroptosis Compound Library | 779 compounds | |
A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; | |||
L2010 | Highly Selective Inhibitor Library | 575 compounds | |
L4020 | NO PAINS Compound Library | 9384 compounds | |
L8720 | Pyroptosis Compound Library | 1066 compounds | |
1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. | |||
L1580 | GPCR Compound Library Plus | 338 compounds | |
Well-chosen 338 GPCR targeting compounds with unique structures; | |||
L8600 | Ubiquitination Compound Library | 210 compounds | |
A unique collection of 210 ubiquitination related small chemicals can be used for high throughput and high content screening; | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L6750 | PBCRBS Traditional Chinese Medicine Compound Library | 580 compounds | |
A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis. | |||
L2193 | Anti-Liver Cancer Compound Library | 1787 compounds | |
1787 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies. | |||
L2191 | Anti-Breast Cancer Compound Library | 1939 compounds | |
A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L2510 | Lipid Metabolism Compound Library | 492 compounds | |
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); | |||
L2560 | Metabolism Compound Library | 2320 compounds | |
L8300 | Chromatin Modification Compound Library | 250 compounds | |
A unique collection of 250 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); | |||
L8110 | Reprogramming Compound Library | 1813 compounds | |
A unique collection of 1813 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. |