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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T16341 | Notch inhibitor 1 | Others | |
Notch inhibitor 1 is an effective Notch inhibitor (IC50s: 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively). Notch inhibitor 1 is also used in the research of cancer. | |||
T19483 | Notch 1 TFA | Others | |
Notch 1 TFA encodes a member of the NOTCH family of proteins. | |||
T3540 | IMR-1A | Gamma-secretase , Drug Metabolite | |
IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L. | |||
T12246 | CB-103 | Gamma-secretase | |
CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity. | |||
T6861 | IMR-1 | Gamma-secretase | |
IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L. | |||
T3075 | FLI-06 | FLI 06 | Gamma-secretase |
FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM). | |||
T6063 | LY-411575 | LY411575 | Apoptosis , Gamma-secretase |
LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM. | |||
T6249 | Avagacestat | BMS-708163 | Gamma-secretase |
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2. | |||
T3633 | Crenigacestat | LY3039478 | Gamma-secretase |
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor mo... | |||
T6202 | DAPT | LY-374973,GSI-IX | Apoptosis , Beta Amyloid , Gamma-secretase , Autophagy |
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis. | |||
T6274 | RO4929097 | RG-4733 | Beta Amyloid , Gamma-secretase |
RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM). | |||
T6125 | Semagacestat | LY450139 | Beta Amyloid , Gamma-secretase |
Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM). | |||
T13410 | ZLDI-8 | Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related | |
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein. | |||
T22678 | 3,5-Bis(4-nitrophenoxy)benzoic acid | Compound W | Gamma-secretase |
3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) is an inhibitor of γ-secretase. It also causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). | |||
T6935 | Nirogacestat | PF-03084014,PF-3084014,PF03084014,PF 03084014 | Apoptosis , Gamma-secretase |
Nirogacestat (PF 03084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay). | |||
T6135 | YO-01027 | gamma-Secretase Inhibitor XX,Dibenzazepine,DBZ | Gamma-secretase |
YO-01027 (DBZ) is a potent γ-secretase inhibitor. | |||
T1602 | Valproic acid sodium salt | Sodium Valproate | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy |
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha... | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
TP1540 | Jagged-1 (188-204) | Jagged-1 188-204 | Gamma-secretase |
Jagged-1 (188-204)is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolay... | |||
T3521 | γ-Secretase-IN-1 | Compound E | Beta Amyloid , Gamma-secretase |
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage. | |||
T14680 | BMS-906024 | Osugacestat,AL-101,BM-0018 | Gamma-secretase |
BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-... | |||
T31987 | Gossypolone | Wnt/beta-catenin , Gamma-secretase | |
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis. | |||
T9015 | LY900009 | Gamma-secretase | |
LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein. | |||
T35566 | RBPJ Inhibitor-1 | RIN1 | Gamma-secretase |
RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell proliferation[1]. | |||
T21890 | JLK6 | Gamma-secretase | |
JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling | |||
T76788 | Demcizumab | OMP 21M18 | Gamma-secretase |
Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent Notch pathway inhibitor. Demcizumab is effective in multiple cancer models, both alone and in combination with chemotherapy agents. | |||
T11718 | JI051 | JI-051 | Gamma-secretase |
JI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inh... | |||
T24159 | IHR-1 | IHR 1 | Smo |
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. | |||
TP1293 | Jagged-1 (188-204) TFA(219127-21-6 free base) | Jagged-1 (188-204) TFA | Gamma-secretase |
Jagged-1 (188-204) TFA(219127-21-6 free base) is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing sub... | |||
T12277 | NVS-ZP7-4 | Others | |
NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7). | |||
T2003 | ISX-9 | Isoxazole 9,Isoxazole 9 (ISX-9) | Calcium Channel , Wnt/beta-catenin |
ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer. | |||
T6870 | L-685458 | L-685,458 | Apoptosis , Gamma-secretase |
L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM. | |||
T15184 | E 2012 | Gamma-secretase | |
E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induc... | |||
TP2117 | SAHM1 | ||
Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly. | |||
T14683 | BMS-983970 | Gamma-secretase | |
T24210 | JNJ-40418677 | ||
JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch. | |||
T35546 | Yhhu 3792 | ||
Notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes... | |||
T76054 | SAHM1 TFA | ||
SAHM1 TFA is a chemical compound that acts as a Notch pathway inhibitor by stabilizing a hydrocarbon-stapled alpha helical peptide. It specifically targets the protein-protein interface, effectively preventing the assemb... | |||
T13917 | TCFA15 | Others | |
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation. | |||
T17281 | Z-Ile-Leu-aldehyde | Z-IL-CHO,GSI-XII,γ-Secretase inhibitor XII | Others |
Z-Ile-Leu-aldehyde is an effective and competitive peptide aldehyde inhibitor of γ-secretase and notch. | |||
T76023 | Jagged-1 (188-204) (TFA) | ||
Jagged-1 (188-204) TFA, a fragment of the Jagged-1 (JAG-1) protein, acts as a Notch agonist. This compound is significantly present in both cultured and primary multiple myeloma (MM) cells, where JAG-1 facilitates the ma... | |||
T12634 | (R)-NVS-ZP7-4 | Others | |
(R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor. NVS-ZP7-4 is the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as... | |||
T73485 | BT-GSI | ||
BT-GSI, a γ-secretase inhibitor (GSI) with bone-targeting capabilities, effectively inhibits Notch signaling. Exhibiting dual action, it possesses both anti-myeloma and anti-resorptive properties, making it a promising c... | |||
T61930 | Yhhu-3792 | ||
Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesi... | |||
T68980 | MRK003 | ||
MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma. MRK003 treatment induced caspase-dependent apoptosis and inhibited proliferation of MM a... | |||
T80615 | Enoticumab | REGN421 | |
Enoticumab (REGN421, SAR153192) is an IgG1κ antibody that specifically targets human Delta-like ligand 4 (Dll4), which serves as a crucial component of the Notch signaling pathway and regulates the uptake of fatty acids ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TWS2045 | Bruceine D | Apoptosis , Antiviral , Gamma-secretase , Parasite | |
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW... | |||
T3399 | Psoralidin | Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial | |
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties. | |||
T4S1990 | Carvacrol | Karvakrol,O-Thymol,cymophenol | Apoptosis , Others , Gamma-secretase , Endogenous Metabolite , Antifungal |
1. Carvacrol (O-Thymol) presents anxiolytic effects. 2. 5-Isopropyl-2-methylphenol presents antinociceptive activity. 3. Carvacrol presents antidepressant effects, seems to be dependent on its interaction with the dopami... | |||
T2842 | Tangeretin | NSC53909,Tangeritin,NSC618905 | Apoptosis , Gamma-secretase |
Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and was also selected as a Notc... | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
T7982 | 3,6-Dihydroxyflavone | Others | |
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway. | |||
T3426 | Bacoside A | MMP , Others , TNF , Dopamine Receptor , NOS , ROS | |
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidat... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-05054 | Notch 4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is i... | |||
TMPY-05081 | Notch 1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Notch 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79.7 kDa and the accession number is P46531. | |||
TMPK-01396 | Notch 3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular dom... | |||
TMPK-01367 | Notch 3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Notch 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 47.7 kDa and the accession number is Q9UM47. | |||
TMPK-01374 | Notch 3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Notch 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 71.53 kDa and the accession number is Q9UM47. | |||
TMPK-01360 | Notch 3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Notch 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 47.7 kDa and the accession number is Q9UM47. | |||
TMPY-04930 | Notch 2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of dev... | |||
TMPK-00868 | Notch 4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression ... | |||
TMPY-02663 | Notch 1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Notch 1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q01705-1. | |||
TMPJ-01452 | Notch 1 Protein, Mouse, Recombinant (aa 18-526, His) | Mouse | HEK293 Cells |
Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531... | |||
TMPY-00415 | Notch 1 Protein, Mouse, Recombinant (hFc) | Mouse | CHO Cells |
Notch 1 Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 80.6 kDa and the accession number is Q01705-1. | |||
TMPK-00465 | Notch 2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Human Notch 2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ... | |||
TMPK-00467 | Notch 1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Notch 1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 56.5 kDa and the accession number is P46531. | |||
TMPK-00466 | Notch 2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ... | |||
TMPK-00468 | Notch 1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Notch 1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 56.5 kDa and the accession number is P46531. | |||
TMPY-05028 | NOTCH2NL Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
NOTCH2NLA (Notch 2 N-Terminal Like A) is a Protein Coding gene. NOTCH2NL, human-specific paralogs of the NOTCH2 receptor, stood out for their ability to promote cortical progenitor maintenance. It belongs to the NOTCH fa... | |||
TMPK-00360 | DLL4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell pro... | |||
TMPH-01783 | NOTCH2NLB Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
NOTCH2NLB Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 31.3 kDa and the accession number is P0DPK3. | |||
TMPH-01784 | NOTCH2NLB Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli |
NOTCH2NLB Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is P0DPK3. | |||
TMPH-02854 | Jagged 1 Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular... | |||
TMPK-01083 | ASPH Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic se... | |||
TMPK-00945 | ASPH Protein, Human, Recombinant (His) | Human | E. coli |
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic se... | |||
TMPY-03276 | BLBP Protein, Human, Recombinant | Human | E. coli |
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic l... | |||
TMPY-03308 | ADAM17 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti... | |||
TMPH-01654 | MAGEA1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal developmen... | |||
TMPK-01030 | LRRN1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction be... | |||
TMPK-01209 | DLL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-00748 | DLL3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-00543 | DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) | Cynomolgus | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPH-02316 | YJEFN3 Protein, Human, Recombinant | Human | E. coli |
May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endotheli... | |||
TMPK-01210 | DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-01206 | DLL3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-00640 | DLL3 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-01207 | DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-01208 | DLL3 Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPK-00542 | DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) | Cynomolgus | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe... | |||
TMPJ-01177 | NOV/CCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor... | |||
TMPH-02217 | SMARCA4 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L4300 | Wnt/Hedgehog/Notch Compound Library | 237 compounds | |
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; | |||
L2600 | Neuronal Signaling Compound Library | 2540 compounds | |
A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L7900 | Osteogenesis Compound Library | 317 compounds | |
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening; | |||
L7700 | Neural Regeneration Compound Library | 524 compounds | |
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; |