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リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T60005	CK1-IN-3		Casein Kinase
	CK1-IN-3 is casein kinase 1 (CK1) inhibitor and can be used for research on the treatment or prevention of diseases associated with circadiantiazol rhythm, inflammation diseases.		Casein Kinase
T5393	CK1-IN-1	PUN51207	p38 MAPK , Casein Kinase
	CK1-IN-1 (PUN51207) is a casein kinase 1 (CK1) inhibitor. CK1-IN-1 has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.		p38 MAPK , Casein Kinase
T79145	CK1-IN-2		Casein Kinase
	CK1-IN-2 (compound Nr.4) is a potent inhibitor of CK1, exhibiting IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a [1].		Casein Kinase
T8987	Epiblastin A		Casein Kinase
	Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).		Casein Kinase
T22884	JW 67		Wnt/beta-catenin
	JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.		Wnt/beta-catenin
T19913	CKI-7	CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl	ROCK , SGK , Casein Kinase , CDK , S6 Kinase
	CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.		ROCK , SGK , Casein Kinase , CDK , S6 Kinase
T61843	CK156
	CK156 is a potent inhibitor of death-associated protein kinase (DAPK), demonstrating high selectivity. In the DRAK1 NanoBRET assay, CK156 exhibits IC50 values of 182 nM, 34 μM, and 39 μM for DRAK1, CK2a1, and CK2a2, resp...
TP1971	Pseudo RACK1
	Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector ...
T27030	CK176	HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34
	CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs).
T71654	APcK110
	APcK110 is a novel Kit inhibitor . APcK110 inhibits proliferation of the mastocytosis cell line HMC1.2 and the SCF-responsive cell line OCI/AML3 in a dose-dependent manner . APcK110 is a more potent inhibitor of OCI/AML3...
T2440	IC261	SU-5607	Apoptosis , Casein Kinase , CDK
	IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.		Apoptosis , Casein Kinase , CDK
T2449	D4476	D 4476,Casein Kinase I Inhibitor	Apoptosis , Casein Kinase , ALK , Autophagy
	D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).		Apoptosis , Casein Kinase , ALK , Autophagy
T6745	5-Iodotubercidin	5-ITu,NSC 113939	Adenosine Receptor
	5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC.		Adenosine Receptor
T4645	TA-01		p38 MAPK , Casein Kinase , Autophagy
	TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.		p38 MAPK , Casein Kinase , Autophagy
T21915	TBCA	Casein Kinase II Inhibitor III, TBCA	Casein Kinase
	TBCA (Casein Kinase II Inhibitor III, TBCA) is a highly selective CK2 (casein kinase II) inhibitor, IC50 = 110 nM, Ki = 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases.		Casein Kinase
T10829	CKI-7 free base	CKI-7	Casein Kinase
	CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.		Casein Kinase
T2695	TBB	Casein Kinase II Inhibitor I,NSC 231634,4,5,6,7-tetrabromobenzotriazole	GSK-3 , Casein Kinase , CDK
	TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).		GSK-3 , Casein Kinase , CDK
T23224	(R)-DRF053 dihydrochloride		Others
	cdk/CK1 inhibitor,potent and ATP-competitive		Others
T16141	MRT00033659		Others
	MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 µM for CK1δ) and CHK1 (IC50=0.23 µM). MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabiliza...		Others
T83684	Myelin Basic Protein Peptide (mouse, bovine) TFA	Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu,MBP Peptide
	Myelin basic protein (MBP) peptide, a selective substrate for protein kinase C (PKC) over protein kinase A (PKA), casein kinase 1 (CK1), CK2, phosphorylase kinase, and calcium/calmodulin-dependent protein kinase (CaMKII)...
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T16507	PF-5006739		Casein Kinase
	PF-5006739 is an effective and selective inhibitor of CK1δ/ε (IC50s: 3.9 nM and 17.0 nM, respectively). PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency...		Casein Kinase
T10298L	AMG-548		p38 MAPK
	AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole b...		p38 MAPK

Compounds

CK1-IN-3

T60005

Synonym:

Target: Casein Kinase

CK1-IN-1

T5393

Synonym: PUN51207

Target: p38 MAPK, Casein Kinase

CK1-IN-2

T79145

Synonym:

Target: Casein Kinase

Epiblastin A

T8987

Synonym:

Target: Casein Kinase

JW 67

T22884

Synonym:

Target: Wnt/beta-catenin

CKI-7

T19913

Synonym: CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl

Target: ROCK, SGK, Casein Kinase, CDK, S6 Kinase

Synonym: HIV-1 inhibitor-34,HIV-1 inhibitor 34,CK 176,CK-176,HIV-1 inhibitor34

Target: Apoptosis, Casein Kinase, CDK

D4476

T2449

Synonym: D 4476,Casein Kinase I Inhibitor

Target: Apoptosis, Casein Kinase, ALK, Autophagy

5-Iodotubercidin

T6745

Synonym: 5-ITu,NSC 113939

Target: Adenosine Receptor

TA-01

T4645

Synonym:

Target: p38 MAPK, Casein Kinase, Autophagy

TBCA

T21915

Synonym: Casein Kinase II Inhibitor III, TBCA

Target: Casein Kinase

CKI-7 free base

T10829

Synonym: CKI-7

Target: Casein Kinase

TBB

T2695

Synonym: Casein Kinase II Inhibitor I,NSC 231634,4,5,6,7-tetrabromobenzotriazole

Target: GSK-3, Casein Kinase, CDK

(R)-DRF053 dihydrochloride

Myelin Basic Protein Peptide (mouse, bovine) TFA

T83684

Synonym: Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu,MBP Peptide

Target: CaMK, Casein Kinase, PKA, PKC

PF-5006739

T16507

Synonym:

Target: Casein Kinase

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04865	Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His)	CHIKV	Baculovirus-Insect Cells
	Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His) is expressed in Baculovirus-Insect cells.
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	Yeast
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-04375	Casein Kinase 1 alpha Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein k...
TMPY-04484	ACK1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. This downstream effector of CDC42 mediates CDC42-dependent cell mig...
TMPJ-00870	NCK1 Protein, Human, Recombinant (His)	Human	E. coli
	Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, ...
TMPH-03364	RBCK1 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	RBCK1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01860	PCK1 Protein, Human, Recombinant (His)	Human	E. coli
	Cytosolic phosphoenolpyruvate carboxykinase that catalyzes the reversible decarboxylation and phosphorylation of oxaloacetate (OAA) and acts as the rate-limiting enzyme in gluconeogenesis. Regulates cataplerosis and anap...
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PK...
TMPY-03405	SPOCK1 Protein, Human, Recombinant (aa 21-429, His)	Human	Baculovirus-Insect Cells
	Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal tes...
TMPY-04402	CSNK1G1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are ...
TMPH-02131	SKP2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle pr...