Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 9,500 | |||
10 mg | 在庫あり | ¥ 15,000 | |||
25 mg | 在庫あり | ¥ 27,000 | |||
50 mg | 在庫あり | ¥ 40,500 | |||
100 mg | 在庫あり | ¥ 60,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,500 |
説明 | 1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2. |
植物由来 |
別名 | 6,8-Dimethoxyumbelliferone, Phytodolor |
分子量 | 222.19 |
分子式 | C11H10O5 |
CAS No. | 486-21-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40 mg/mL(180 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
You can also refer to dose conversion for different animals. 詳細
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Isofraxidin 486-21-5 Immunology/Inflammation MAPK Neuroscience Proteases/Proteasome COX TLR p38 MAPK MMP ERK 6,8-Dimethoxyumbelliferone Cyclooxygenase inhibit hepatoma Matrix metalloproteinases MD-2 COX-2 invasion TLR4 iNOS ERK1/2 MMP-7 cell Phytodolor Inhibitor Toll-like Receptor (TLR) inhibitor