Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.
説明 | FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively. |
ターゲット&IC50 | mGluR1(human):5.8 nM, mGluR1(mouse):3.1 nM |
分子量 | 358.41 |
分子式 | C18H23FN6O |
CAS No. | 873551-53-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 35.8 mg/mL(100 mM)
You can also refer to dose conversion for different animals. 詳細
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FTIDC 873551-53-2 Neuroscience GluR mGluR Metabotropic glutamate receptors inhibit Inhibitor inhibitor