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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5424 | Etosalamide | Ethosalamide | Others |
Etosalamide (Ethosalamide) is an antipyretic and analgesics agent. | |||
T0734 | Antipyrine | Phenazone,Phenazon | COX |
Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver. | |||
T0778 | Phenacetin | Acetophenetidin | COX |
Phenacetin (Acetophenetidin) is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. | |||
T10152 | 4-Methylamino antipyrine | COX , Drug Metabolite | |
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relativel... | |||
T0456 | Cinchophen | Cinconal | COX |
Cinchophen (Cinconal), an analgesic drug, is utilized in treating gout. | |||
T1191L | Metamizole sodium | Analgin,Dipyron | COX |
Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE. | |||
T27635 | Isoxepac | Olopatadine USP Related Compound C | Others |
Isoxepac (Olopatadine USP Related Compound C) is a non-steroidal anti-antiphlogistic agent and analgesic. | |||
T0859 | Fenbufen | CL-82204,Lederfen | ATPase , Caspase , COX |
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractur... | |||
T0448 | (S)-(+)-Ibuprofen | Dexibuprofen,(S)-Ibuprofen | BCL , Thrombin , Cysteine Protease , COX , PPAR |
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX). | |||
T0005 | Aspirin | Acetylsalicylate,Acetylsalicylic Acid,ASA | Mitophagy , Virus Protease , COX , Autophagy |
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel... | |||
T19679 | Benoxaprofen | NSC 299582,LY-90459,Benoxaphen. Compound 90459 | COX |
Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug. | |||
T12533 | Piperylone | PR66 | Others |
Piperylone (PR66) has anti-spasmodic, analgesic, anti-inflammatory and antipyretic activities. | |||
T3608 | Carbasalate calcium | Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium | Platelet aggregation |
Carbasalate calcium (Rheomin) is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor. | |||
T16950 | Sudoxicam | 4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide | COX |
Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema, and antipyretic properties. | |||
T19641 | Epirizole | DA 398,Mepirizole,DA398,Mebron,Methopyrimazole,Dalex,DA-398 | Others |
Epirizole (Mebron) shows antipyretic, analgesic, and anti-inflammatory activity and can be used in studies about chronic rheumatoid arthritis. | |||
T6687 | Suprofen | Maldocil,Suprol,TN-762,Profenal | COX , PGE Synthase |
Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. | |||
T0442 | Bucetin | 3-Hydroxy-p-butyrophenetidide | Others |
Bucetin (3-Hydroxy-p-butyrophenetidide) is a pharmaceutical drug that acts as an analgesic and antipyretic. Bucetin was withdrawn from use in 1986 due to renal toxicity. | |||
T22307 | Diclofenac Epolamine | diclofenac hydroxyethylpyrrolidine,DHEP,DIEP | Others |
Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions. | |||
T0890 | Mefenamic acid | CN-35355,CI 473 | COX |
Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase. | |||
T19672 | Amtolmetin guacil | MED 15,MED15,ST679,ST-679,ST 679,MED-15 | COX |
Amtolmetin guacil (ST-679) inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties. | |||
T7238 | 2-Acetamidophenol | Orthocetamol | |
2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol). | |||
T1209 | Flunixin meglumine | Banamine,Finadyne,Flunixin meglumin | COX |
Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity. | |||
T0058 | 2-Ethoxybenzamide | Ethenzamide,Anovigam | COX |
2-Ethoxybenzamide (Anovigam) is white or almost-white crystalline powder. Almost odorless. Tasteless. It is widely used as an antipyretic anodyne. | |||
T1586 | Tenoxicam | Ro-12-0068,Tenoxicamum,Mobiflex,Tilcotil | COX |
Tenoxicam (Tilcotil), an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. | |||
T1133 | Nimesulide | R805 | COX |
Nimesulide (R805) is a relatively COX-2 selective inhibitor with analgesic and antipyretic properties. | |||
T1582L | Naproxen sodium | Miranax,Anaprox,RS-3650,Naprelan | COX , Autophagy |
Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties. | |||
T5010 | Propyphenazone | Isopropylantipyrine,Propyphenazone (4-Isopropylantipyrine),Isopropylphenazone,4-Isopropylantipyrine,Isopropyrine | COX |
Propyphenazone (4-Isopropylantipyrine), a pyrazolone derivative, exhibits anti-inflammatory, analgesic, and antipyretic properties and acts as a precursor for prodrugs and selective cyclooxygenase-2 inhibitors. | |||
T0867 | Bufexamac | Bufexamic acid | COX , HDAC |
Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action. | |||
T0858 | Flufenamic acid | Arlef,Nichisedan,Achless | Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite |
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. | |||
T3276 | Benorilate | Benortan,Benoral,Salipran,Benorylate | Prostaglandin Receptor |
Benorilate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties. | |||
T1191 | Metamizole sodium hydrate | Sulpyrine,Analgin,Dipyron hydrate | COX |
Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX). Target: COX Dipyrone is a potent analgesic and antipyretic drug that has been used clinically for... | |||
T1582 | Naproxen | (S)-Naproxen | COX , Autophagy |
Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. | |||
T27312 | Fentiazac | Donorest,Flogene,BR-700 | Others |
Fentiazac(BR-700) is an orally active nonsteroidal alkanoic acid derivative with significant analgesic, anti-inflammatory, and antipyretic activity.Fentiazac is used in the study of inflammatory diseases such as rheumato... | |||
T1212 | Ketorolac tromethamine salt | Acular LS,Toradol,Ketorolac tris salt,Acular | COX |
Ketorolac tromethamine salt (Ketorolac tris salt) non-selective inhibits the enzymes cyclooxygenase 1 (COX-1) and COX-2with anti-inflammatory, analgesic, and antipyretic activities. | |||
T1325 | Carprofen | Ridamyl,Imadyl,Rimadyl | FAAH , COX , Autophagy |
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. | |||
T8807 | Benzydamine | Others | |
Benzydamine is a benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. Benzydamine is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. | |||
T0914 | Metacetamol | 3-Acetamidophenol | Others |
Metacetamol (3-Acetamidophenol) is a derivative of acetaminophen, a non-toxic regional isomer of acetaminophen. It is an over-the-counter analgesic and antipyretic and is also used as an organic synthesis intermediate. | |||
T0260 | Meclofenamic acid sodium | Meclofenamate Sodium,Movens,Meclomen,Meclonax | Gap Junction Protein , COX |
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis. | |||
T0498 | Salsalate | Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171 | Reactive Oxygen Species , COX |
Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities. | |||
T0855 | (R)-Naproxen | COX | |
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis... | |||
TP2212L | A-MSH, amide Acetate(581-05-5 free base) | Melanocortin Receptor | |
a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelano... | |||
T1432 | Phenylbutazone | Butazolidine | COX |
Phenylbutazone (Butazolidine) is a butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ankylosing spondylitis, rheumatoid arthritis, and reactive arthri... | |||
T1555 | Diclofenac sodium | GP 45840 | Apoptosis , COX |
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. | |||
T0291 | Flurbiprofen | dl-Flurbiprofen | Apoptosis , COX , MRP |
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE. | |||
T1002 | Etodolac | Ultradol,AY-24236,Etodolic acid,Lodine | Retinoid Receptor , COX |
Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ... | |||
T1394 | Ibuprofen | Brufen,(±)-Ibuprofe,Motrin,Advil | COX |
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu... | |||
T15181 | DuP-697 | COX | |
DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic... | |||
T0839 | Ketoprofen | RP-19583 | Apoptosis , COX , MRP |
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas... | |||
T1574 | Etoricoxib | Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine | COX |
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenas... | |||
T1185 | Rofecoxib | MK 966,MK-0966 | COX |
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of pheny... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T6S1435 | Notopterol | Apoptosis , Others | |
1. Notopterol induces apoptosis and inhibits cell cycle-specific. | |||
TN1650 | Friedelin | P450 , NOS , Caspase , Prostaglandin Receptor | |
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities. | |||
T4842 | 1H-pyrazole | 1,2-Diazole,Pyrazole | Others , Endogenous Metabolite |
1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythm... | |||
T0065 | Acetaminophen | 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol | COX , Endogenous Metabolite , Histone Acetyltransferase |
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity. | |||
T0004 | Salicylamide | Salamide,2-Hydroxybenzamide | COX |
Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin. In the over-the-counter pain remedies, Salicylamide is used in c... | |||
TN1215 | (2S)-2'-Methoxykurarinone | 2'-Methoxykurarinone,2'-O-Methylkurarinone | Akt , Antifection |
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo... | |||
T5S1708 | Dendrobine | Others , Influenza Virus | |
1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. 3. Dendrobine on the ele... | |||
T5592 | Acetosyringone | Acetosyringenin | Others |
Acetosyringone (Acetosyringenin)(AS) is a phenol secreted by wounded plant tissues.Acetosyringone is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions. | |||
T1468 | Lornoxicam | Ro 13-9297,Chlortenoxicam,TS110 | COX , Endogenous Metabolite |
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co... | |||
T6S1684 | 8-Gingerol | Antioxidant , Antibacterial , TRP/TRPV Channel | |
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic... | |||
T6S1699 | Shogaol | [6]-Shogaol,6-Shogaol | Lipoxygenase , Autophagy |
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f... | |||
T4S1551 | Cinnamaldehyde | Cinnamic Aldehyde | HIF |
1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express... | |||
T82533 | Donasine | ||
Donasine, an indole alkaloid naturally derived from the rhizomes of Arundo donax L. [1], exhibits antipyretic properties. |