Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, which was the source of cytoprotective prostaglandins in gastric epithelium.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 24,000 | |||
5 mg | 在庫あり | ¥ 55,000 | |||
10 mg | 在庫あり | ¥ 81,000 | |||
25 mg | 在庫あり | ¥ 136,500 | |||
50 mg | 在庫あり | ¥ 195,000 | |||
100 mg | 在庫あり | ¥ 268,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 63,000 |
説明 | Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, which was the source of cytoprotective prostaglandins in gastric epithelium. |
In vitro | The synthesis of Gaultherin (1) and its analogs was carried out to provide 11 glycosides under phase-transfer catalytic conditions. METHODS AND RESULTS: The activities of all synthesized compounds were evaluated by nitric oxide production inhibitory assay in vitro. Methyl 2-O-(4-O-β-d-galactopyranosyl)-β-d-glucopyranosylbenzoate (5f) showed significantly anti-nociceptive and anti-inflammatory effects by the evaluation in vivo. Structure-activity relationships within these compounds were discussed. |
植物由来 |
分子量 | 446.4 |
分子式 | C19H26O12 |
CAS No. | 490-67-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (112.01 mM)
You can also refer to dose conversion for different animals. 詳細
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Gaultherin 490-67-5 Immunology/Inflammation Neuroscience COX salicylate NSAID Gaultheria yunnanensis Inhibitor analgesic anti-inflammatory inhibit non-steroidal inhibitor