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Search Results for " non-steroidal "

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167

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9

天然化合物

1

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カタログ番号 製品名 別名 ターゲット
T2550 Tolmetin Tolectin COX
Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification of tolmetin is Nonsteroidal Anti-inflammatory Compounds.
T11399 Giredestrant GDC-9545 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand,...
T0380 Bicalutamide ICI-176334 Androgen Receptor , Autophagy
Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.
T6737 Zaltoprofen CN100,Soleton COX
Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.
T22371 Mivacurium dichloride Mivacurium chloride AChR
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg...
T26539 AC-262536 AC262536 Androgen Receptor
AC-262536 is a selective androgen receptor (SAR) modulator. It has partial agonist activity with respect to testosterone and suppresses luteinizing hormone.
T0383 Fenspiride hydrochloride Fenspiride HCl,Pneumorel,Fluiden,Decaspiride Adrenergic Receptor , PDE , Histamine Receptor
Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory ...
T25985 Prifelone R-830,R830,S-16820,S 16820,R 830
Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.
T26109 Robenacoxib Onsior COX
Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity.
T6540 Ibuprofen Lysine Neoprofen COX
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.
T0321 Indoprofen (±)-Indoprofe COX
Indoprofen ((±)-Indoprofe) is a non-steroidal anti-inflammatory drug.
T19679 Benoxaprofen NSC 299582,LY-90459,Benoxaphen. Compound 90459 COX
Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.
T6498 Fenoprofen calcium hydrate Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate Apoptosis , Others , COX
Fenoprofen calcium hydrate (Progesic dihydrate) is a non-steroidal anti-inflammatory drug (NSAID).
T21740 RD162 Androgen Receptor
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
T7839 Lasofoxifene Tartrate CP-336156 Estrogen Receptor/ERR
Lasofoxifene Tartrate (CP-336156) is a third-generation, non-steroidal selective estrogen receptor modulator.
T14546 Bermoprofen AD-1590,AJ-1590 Others
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.
T27209 Droxicam Droxicamum Others
Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal disorders.
T27635 Isoxepac Olopatadine USP Related Compound C Others
Isoxepac (Olopatadine USP Related Compound C) is a non-steroidal anti-antiphlogistic agent and analgesic.
T15246 Esaxerenone XL-550,CS-3150 Glucocorticoid Receptor
Esaxerenone (XL-550) is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.
T11340 Furprofen Prostaglandin Receptor
Furprofen, a non-steroidal anti-inflammatory drug (NSAID), exerts its effects by inhibiting the synthesis of prostaglandin (PGE). This compound demonstrates analgesic properties and can be conveniently administered orall...
T0184 Fenoprofen calcium dihydrate COX
Fenoprofen calcium is a propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.
T0055 Glafenine Glafenin COX
Glafenine (Glafenin), a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of various origins.
T19694 Hydronidone F351,F-351,F 351 Others
Hydronidone (F-351) is Non-Steroidal Antiinflammatory Drugs. It potentially for the treatment of hepatic fibrosis.
T7389 G15 Estrogen Receptor/ERR
G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM)
T1720 Amfenac Sodium Hydrate Amfenac Sodium Monohydrate COX
Amfenac Sodium Hydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety.
T22307 Diclofenac Epolamine diclofenac hydroxyethylpyrrolidine,DHEP,DIEP Others
Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.
T0463 Loxoprofen Loxoprofene,Loxoprofeno,Koloxo COX
Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.
T7313 Enclomiphene citrate Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate Estrogen Receptor/ERR
Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
T14666 BL-1249 Potassium Channel
BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).
T0637 2-Acetyl-6-methoxynaphthalene Others
2-Acetyl-6-methoxynaphthalene, the key intermediate of naphthalene tome and naproxen, is used in synthetic non-steroidal anti-inflammatory analgesic medicine and.
T5843 Tarenflurbil MPC7869,(R)-Flurbiprofen,R-flurbiprofen Retinoid Receptor , Autophagy
Tarenflurbil ((R)-Flurbiprofen) is the non-cyclooxygenase inhibiting R-enantiomer of the non-steroidal anti-inflammatory drug flurbiprofen, which was assessed as a remedy for Alzheimer's disease.
T12361 Parcetasal MR-897 Others
Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.
T4542 Clonixin Clonixic acid Others
Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.
T4561 Tiaprofenic acid Tiaprofensaeure,Acido tiaprofenico,Surgam Others , COX
Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
T1258 Nabumetone BRL14777 COX , Glutathione Peroxidase
Nabumetone (BRL14777)(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
T0448 (S)-(+)-Ibuprofen Dexibuprofen,(S)-Ibuprofen BCL , Thrombin , Cysteine Protease , COX , PPAR
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
T0767 Sulfapyridine Sulfidine,Sulfidin,2-Sulfapyridine Antibacterial , Antibiotic , Autophagy
Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.
T21412 Ketorolac Toradol,Sprix,Acuvail,Macril,Acular COX
Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.
T1421 Aceclofenac Preservex,Airtal COX
Aceclofenac (Preservex) is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties.
T0890 Mefenamic acid CN-35355,CI 473 COX
Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
T0285 Isoxicam Isoxicamum,Isoxicamo,Maxicam COX
Isoxicam (Isoxicamum) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
T0159 Pranoprofen Pyranoprofen Apoptosis , COX , PGE Synthase , Prostaglandin Receptor
Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.
T0484 Deracoxib SC 46,SC 046,SC 59046 Apoptosis , COX
Deracoxib (SC 46) is a non-steroidal, non-narcotic anti-inflammatory drug. It is also a selective cyclooxygenase-2 inhibitor, and IC50 Value: 70 to 150 μM(inhibition of 3 osteosarcoma cell lines).
T30161 EN3356 AS N001,ASN-001 P450
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and ant...
T19967 Fendosal HP 129,P 71-0129,P71-0129,P-71-0129,HP129,HP-129 Immunology/Inflammation related
Fendosal (HP-129) is a non-steroidal anti-inflammatory agent. It is 6.9 to 9.5 times more active than aspirin in the prophylactic and therapeutic adjuvant-induced polyarthritis models of chronic inflammation.
T12481 Pipecuronium bromide RGH-1106 AChR
Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics.
T7363 Ibuprofen Piconol U75630 Others
Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen.
T0319 Suxibuzone Calibene,Suxibuzonum,Suxibuzona COX
Suxibuzone (Suxibuzona) is a drug used for joint and muscular pain. It is a prodrug of the non steroidal anti inflammatory drug phenylbutazone, and is commonly used in horses.
T26926 Butibufen FF 105,FF-106,FF 106,FF106 Lipoxygenase
Butibufen (FF-106) is an orally active non-steroidal anti-inflammatory compound, a potential cyclooxygenase inhibitor with analgesic and antipyretic activity, and inhibits urea synthesis.Butibufen has been used in the st...
T2553 Etofenamate COX
Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.

Compounds

Tolmetin
T2550
Synonym: Tolectin
Target: COX
Giredestrant
T11399
Synonym: GDC-9545
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
Bicalutamide
T0380
Synonym: ICI-176334
Target: Androgen Receptor, Autophagy
Zaltoprofen
T6737
Synonym: CN100,Soleton
Target: COX
Mivacurium dichloride
T22371
Synonym: Mivacurium chloride
Target: AChR
AC-262536
T26539
Synonym: AC262536
Target: Androgen Receptor
Fenspiride hydrochloride
T0383
Synonym: Fenspiride HCl,Pneumorel,Fluiden,Decaspiride
Target: Adrenergic Receptor, PDE, Histamine Receptor
Prifelone
T25985
Synonym: R-830,R830,S-16820,S 16820,R 830
Target:
Robenacoxib
T26109
Synonym: Onsior
Target: COX
Ibuprofen Lysine
T6540
Synonym: Neoprofen
Target: COX
Indoprofen
T0321
Synonym: (±)-Indoprofe
Target: COX
Benoxaprofen
T19679
Synonym: NSC 299582,LY-90459,Benoxaphen. Compound 90459
Target: COX
Fenoprofen calcium hydrate
T6498
Synonym: Feprona dihydrate,Fenoprofen calcium salt dihydrate,Progesic dihydrate
Target: Apoptosis, Others, COX
RD162
T21740
Synonym:
Target: Androgen Receptor
Lasofoxifene Tartrate
T7839
Synonym: CP-336156
Target: Estrogen Receptor/ERR
Bermoprofen
T14546
Synonym: AD-1590,AJ-1590
Target: Others
Droxicam
T27209
Synonym: Droxicamum
Target: Others
Isoxepac
T27635
Synonym: Olopatadine USP Related Compound C
Target: Others
Esaxerenone
T15246
Synonym: XL-550,CS-3150
Target: Glucocorticoid Receptor
Furprofen
T11340
Synonym:
Target: Prostaglandin Receptor
Fenoprofen calcium dihydrate
T0184
Synonym:
Target: COX
Glafenine
T0055
Synonym: Glafenin
Target: COX
Hydronidone
T19694
Synonym: F351,F-351,F 351
Target: Others
G15
T7389
Synonym:
Target: Estrogen Receptor/ERR
Amfenac Sodium Hydrate
T1720
Synonym: Amfenac Sodium Monohydrate
Target: COX
Diclofenac Epolamine
T22307
Synonym: diclofenac hydroxyethylpyrrolidine,DHEP,DIEP
Target: Others
Loxoprofen
T0463
Synonym: Loxoprofene,Loxoprofeno,Koloxo
Target: COX
Enclomiphene citrate
T7313
Synonym: Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate
Target: Estrogen Receptor/ERR
BL-1249
T14666
Synonym:
Target: Potassium Channel
2-Acetyl-6-methoxynaphthalene
T0637
Synonym:
Target: Others
Tarenflurbil
T5843
Synonym: MPC7869,(R)-Flurbiprofen,R-flurbiprofen
Target: Retinoid Receptor, Autophagy
Parcetasal
T12361
Synonym: MR-897
Target: Others
Clonixin
T4542
Synonym: Clonixic acid
Target: Others
Tiaprofenic acid
T4561
Synonym: Tiaprofensaeure,Acido tiaprofenico,Surgam
Target: Others, COX
Nabumetone
T1258
Synonym: BRL14777
Target: COX, Glutathione Peroxidase
(S)-(+)-Ibuprofen
T0448
Synonym: Dexibuprofen,(S)-Ibuprofen
Target: BCL, Thrombin, Cysteine Protease, COX, PPAR
Sulfapyridine
T0767
Synonym: Sulfidine,Sulfidin,2-Sulfapyridine
Target: Antibacterial, Antibiotic, Autophagy
Ketorolac
T21412
Synonym: Toradol,Sprix,Acuvail,Macril,Acular
Target: COX
Aceclofenac
T1421
Synonym: Preservex,Airtal
Target: COX
Mefenamic acid
T0890
Synonym: CN-35355,CI 473
Target: COX
Isoxicam
T0285
Synonym: Isoxicamum,Isoxicamo,Maxicam
Target: COX
Pranoprofen
T0159
Synonym: Pyranoprofen
Target: Apoptosis, COX, PGE Synthase, Prostaglandin Receptor
Deracoxib
T0484
Synonym: SC 46,SC 046,SC 59046
Target: Apoptosis, COX
EN3356
T30161
Synonym: AS N001,ASN-001
Target: P450
Fendosal
T19967
Synonym: HP 129,P 71-0129,P71-0129,P-71-0129,HP129,HP-129
Target: Immunology/Inflammation related
Pipecuronium bromide
T12481
Synonym: RGH-1106
Target: AChR
Ibuprofen Piconol
T7363
Synonym: U75630
Target: Others
Suxibuzone
T0319
Synonym: Calibene,Suxibuzonum,Suxibuzona
Target: COX
Butibufen
T26926
Synonym: FF 105,FF-106,FF 106,FF106
Target: Lipoxygenase
Etofenamate
T2553
Synonym:
Target: COX
1 2 3 4
カタログ番号 製品名 別名 ターゲット
T3S0509 Gaultherin COX
Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w...
TN2282 Trans-Stilbene 1,2-Diphenylethylene (trans),(E)-Stilbene Others
trans-Stilbene (1,2-Diphenylethylene (trans)) is a natural product used in the manufacture of dye lasers, optical brighteners, and non-steroidal synthetic estrogens.
T4000 (±)-Equol Equol,(R,S)-Equol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Drug Metabolite
(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occu...
T6491 (-)-(S)-Equol (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
T13577 β-Zearalenol Others
β-Zearalenol, a non-steroidal estrogenic mycotoxin synthesized by Fusarium species, potentially influences transcription and affects gene expression on the translational level.
T36893 4-oxo Withaferin A
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1...
T81132 Soladulcoside A
Soladulcoside A, a steroidal glycoside with antineoplastic properties, is derived from the entire Solanum nigrum plant. It demonstrates inhibitory effects on A549 cells, suggesting its applicability in researching non-sm...
T35647 4-oxo-27-TBDMS Withaferin A
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/...
T35667 Napyradiomycin A1 Napyradiomycin A1
Napyradiomycin A1is a fungal metabolite originally isolated fromC. rubraand has diverse biological activities.1,2It is active againstS. aureus,M. luteus,B. anthracis,C. bovis, andM. smegmatis(MICs = 1.56-12.5 μg/ml).1Nap...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-01640 MRGPRX2 Protein, Human, Recombinant (His) Human E. coli
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules ...
カタログ番号 製品名
L4710 Nonsteroidal Anti-Inflammatory Compound Library

530 compounds
530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.
L6710 Anti-Inflammatory Traditional Chinese Medicine Compound Library

1246 compounds
A collection of 1246 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study;
L4700 Immunology/Inflammation Compound Library

4720 compounds
A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening.