Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.
説明 | ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42. |
ターゲット&IC50 | Rac1:20.17 nM(wild type,EC50), Rac1:25.42 nM(activated mutant,EC50), Cell division cycle 42:100 nM(wild type,EC50), Cell division cycle 42:58.88 nM(activated mutant,EC50), Ras:95.5 nM(activated mutant,EC50) |
In vitro | ML-099 activates Ras protein wild type(EC50 = 141.25 nM), Rab7(EC50 = 181.97 nM), Rab-2A(EC50 = 354.81 nM), Rac1 protein activated mutant(EC50 = 25.42 nM), Rac1 protein wild type(EC50 = 20.17 nM), Ras protein activated mutant(EC50 = 95.5 nM), cell division cycle 42 activated mutant(EC50 = 58.88 nM) and cell division cycle 42 wild type(EC50 = 100 nM)[1]. |
分子量 | 259.32 |
分子式 | C14H13NO2S |
CAS No. | 496775-95-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (192.81 mM)
You can also refer to dose conversion for different animals. 詳細
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ML-099 496775-95-2 Cell Cycle/Checkpoint GPCR/G Protein MAPK Rho Ras inhibit Inhibitor CID 888706 Rab7 Rac1 ab-2A ML 099 CID888706 ML099 CID-888706 inhibitor