Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.
説明 | Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. |
ターゲット&IC50 | COX-2:0.1 μg/mL (IC50) |
別名 | CG-100649, CG100649, CG 100649 |
分子量 | 361.39 |
分子式 | C18H16FNO4S |
CAS No. | 301692-76-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: 55 mg/ml (152.19 mM)
You can also refer to dose conversion for different animals. 詳細
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Polmacoxib 301692-76-2 Immunology/Inflammation Metabolism Neuroscience COX Carbonic Anhydrase NSAID inflammatory polyp colorectal adenoma tumor Inhibitor CG-100649 Cyclooxygenase inhibit Carbonate dehydratase CG100649 orthotopic CG 100649 inhibitor