Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mechanism of UVA breaking DNA structure.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 66,500 | |||
10 mg | 在庫あり | ¥ 105,500 | |||
25 mg | 在庫あり | ¥ 189,000 | |||
50 mg | 在庫あり | ¥ 250,500 |
説明 | Pterine-6-carboxylic acid (6-Carboxypterin) is a photodegradation product of folic acid, which can be used as a photosensitive agent to study the molecular mechanism of UVA breaking DNA structure. |
In vitro | Pterin-6-carboxylic acid induces DNA photooxidation specifically at consecutive G residues through electron transfer[1]. Pterin-6-carboxylic acid bind to the active site of phosphodiesterase 5 with the binding energy value of -7.1 and 2.05A° 2.23A° when compared with other compound found in the plant. In silico studies hypothesized that pterin-6-carboxylic acid can be an inhibitory agent for PDE5 protein which could be a potential drug candidate for the treatment of erectile dysfunction[2]. |
別名 | 6-Carboxypterin |
分子量 | 207.15 |
分子式 | C7H5N5O3 |
CAS No. | 948-60-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Pterine-6-carboxylic acid 948-60-7 DNA Damage/DNA Repair Metabolism DNA PDE 6-Carboxypterin Inhibitor inhibitor inhibit