Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.
説明 | Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus. |
ターゲット&IC50 | JAK1:8-9 nM |
キナーゼ試験 | In vitro HotSpotSM kinase profiling of 289 kinases is performed. The assay is conducted in the presence of 10 μM [33P]-ATP, using brigatinib concentrations ranging from 0.05 nM to 1 μM. |
別名 | GLPG-0778, GSK-2586184 |
分子量 | 389.45 |
分子式 | C22H23N5O2 |
CAS No. | 1206163-45-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL(51.4 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Solcitinib 1206163-45-2 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells JAK GLPG0778 Janus kinase GLPG 0778 Inhibitor GSK 2586184 inhibit GLPG-0778 GSK2586184 GSK-2586184 inhibitor