Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 9,500 | |||
5 mg | 在庫あり | ¥ 22,000 | |||
10 mg | 在庫あり | ¥ 38,000 | |||
25 mg | 在庫あり | ¥ 73,500 | |||
50 mg | 在庫あり | ¥ 110,000 | |||
100 mg | 在庫あり | ¥ 158,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. |
ターゲット&IC50 | MDA-MB-231 cells:29.7 μM (IC50) |
In vitro | Sophoraflavanone G (0 -100 μM; 24 hours) decreases the viability of the HL-60 cells in a dose-dependent manner, and induces HL-60 cell apoptosis, activated caspase-3 and caspase-9, and downregulated Bcl-2 and Bcl-xL. It also upregulates Bax and released cytochrome c from the mitochondria into the cytoplasm, enabling apoptosis via the mitochondrially-mediated 'intrinsic' pathway [1]. Sophoraflavanone G (0 -40 μM; 24 hours) inhibits MDA-MB-231 cell viability in a concentration-dependent manner (IC50: 29.7 μM) [2]. |
植物由来 |
別名 | Kushenol F, Vexibinol |
分子量 | 424.49 |
分子式 | C25H28O6 |
CAS No. | 97938-30-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (58.89 mM)
You can also refer to dose conversion for different animals. 詳細
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Sophoraflavanone G 97938-30-2 Apoptosis Inhibitor anti-infammatory HL60 inhibit Kushenol F Vexibinol inhibitor