Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.
説明 | Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration. |
ターゲット&IC50 | VEGFR2:700 nM |
別名 | Tyrphostin SU 1498, AG 1498 |
分子量 | 390.52 |
分子式 | C25H30N2O2 |
CAS No. | 168835-82-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (384.10 mM)
You can also refer to dose conversion for different animals. 詳細
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Su1498 168835-82-3 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Vascular endothelial growth factor receptor Inhibitor Su-1498 Tyrphostin SU 1498 inhibit AG1498 AG-1498 Tyrphostin SU-1498 Tyrphostin SU1498 SU 1498 AG 1498 inhibitor