Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 20,500 | |||
10 mg | 在庫あり | ¥ 35,500 | |||
25 mg | 在庫あり | ¥ 60,500 | |||
50 mg | 在庫あり | ¥ 89,500 | |||
100 mg | 在庫あり | ¥ 131,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells. |
ターゲット&IC50 | IL-2:21 nM (IC50), MLR:30 nM (IC50), JAK3:72 nM (IC50), p38α:3 nM (IC50), Lck:0.2 nM (IC50), VEGF2:1 nM (IC50) |
分子量 | 535.56 |
分子式 | C29H28F3N5O2 |
CAS No. | 882663-88-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 34 mg/mL (63.48 mM)
You can also refer to dose conversion for different animals. 詳細
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AMG-47a 882663-88-9 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling MAPK Stem Cells Tyrosine Kinase/Adaptors p38 MAPK VEGFR JAK Src Inhibitor signal kinases AMG 47a Janus kinase transduction cytoplamic cell AMG47a inhibit receptor specific responses Vascular endothelial growth factor receptor immune tyrosine family inhibitor