Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.
説明 | TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors. |
In vivo | TQS reduces LPS-induced IκB and CD11b gene expression and microglial activation associated with hyperalgesia and allodynia by targeting microglial α7 nAChR in the hippocampus[1]. |
別名 | 4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide |
分子量 | 376.47 |
分子式 | C22H20N2O2S |
CAS No. | 353483-92-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 240 mg/mL (637.50 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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TQS 353483-92-8 Neuroscience AChR Inhibitor modulator acetylcholine Nicotinic acetylcholine receptors nAChR allosteric neuroinflammatory positive pain inhibit 4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide nicotinic inhibitor