Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 12,000 |
2 mg | 在庫あり | ¥ 17,000 |
5 mg | 在庫あり | ¥ 23,500 |
10 mg | 在庫あり | ¥ 40,500 |
25 mg | 在庫あり | ¥ 78,000 |
50 mg | お問い合わせ | ¥ 137,500 |
100 mg | お問い合わせ | ¥ 196,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 40,500 |
説明 | UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3. |
ターゲット&IC50 | FLT3:0.74 nM, Mer:0.8 nM |
In vivo | UNC2025 was capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. |
分子量 | 549.62 |
分子式 | C28H42Cl2N6O |
CAS No. | T4419 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.5 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
UNC2025 2HCl (1429881-91-3(free base)) T4419 Angiogenesis Tyrosine Kinase/Adaptors TAM Receptor FLT UNC-2025 2HCl (1429881-91-3(free base)) UNC2025 2HCl (1429881913(free base)) UNC2025 2HCl (1429881 91 3(free base)) Inhibitor inhibitor inhibit