store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 7,000 | |||
10 mg | 在庫あり | ¥ 12,000 | |||
25 mg | 在庫あり | ¥ 25,000 | |||
50 mg | 在庫あり | ¥ 42,000 | |||
100 mg | 在庫あり | ¥ 66,000 | |||
500 mg | 在庫あり | ¥ 158,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,000 |
説明 | Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition. |
ターゲット&IC50 | Anti-mitotic:1.25 nM |
In vitro | Vinorelbine inhibits microtubule assembly by inducing tubulin aggregation into spirals and paracrystals. [1] Vinorelbine shows potent antiproliferative activity against a series of tumor cells, including human melanoma, non-small-cell lung cancer, breast cancer, etc. [2][3][4] |
In vivo | In vivo, Vinorelbine also shows antitumour activity against a series of subcutaneously-implanted human tumour xenografts. [5] |
植物由来 |
別名 | Vinorelbine Tartrate, Nor-5'-anhydrovinblastine ditartrate, KW-2307, Navelbine tartrate |
分子量 | 1079.11 |
分子式 | C45H54N4O8·2C4H6O6 |
CAS No. | 125317-39-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 107.9 mg/mL (100 mM)
DMSO: 55 mg/mL (50.97 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Vinorelbine ditartrate 125317-39-7 Autophagy Cytoskeletal Signaling Microtubule Associated Vinorelbine Tartrate Nor-5'-anhydrovinblastine ditartrate Inhibitor KW-2307 Nor-5'-anhydrovinblastine Vinorelbine KW 2307 Microtubule/Tubulin Navelbine tartrate Nor-5'-anhydrovinblastine Ditartrate KW2307 Vinorelbine Ditartrate inhibit Navelbine Tartrate inhibitor