Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 101,000 | |||
10 mg | 在庫あり | ¥ 149,000 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
100 mg | 在庫あり | ¥ 429,500 | |||
500 mg | 在庫あり | ¥ 856,000 |
説明 | Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2]. |
ターゲット&IC50 | 5-HT2B:27 μM, 5-HT2C:32 μM(EC50) |
In vivo | Viloxazine (1-16 mg/kg; spinal rat) stimulated the hind limb flexor reflex in the dose-dependent manner.[3] |
別名 | Emovit, Viloxazin |
分子量 | 237.29 |
分子式 | C13H19NO3 |
CAS No. | 46817-91-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (252.86 mM)
You can also refer to dose conversion for different animals. 詳細
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Viloxazine 46817-91-8 GPCR/G Protein Neuroscience 5-HT Receptor Norepinephrine Emovit Viloxazin Inhibitor inhibitor inhibit