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カタログ番号 | 製品名 | 別名 | ターゲット |
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T22554 | Adenosine Kinase Inhibitor (hydrate) | Others | |
Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations. Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without produc... | |||
T14944 | CGS 15943 | PI3K , Adenosine Receptor | |
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively. | |||
T84880 | ABT-702 hydrochloride | Adenosine Kinase Inhibitor hydrochloride | Others |
ABT-702 hydrochloride effectively inhibits adenosine kinase, exhibiting an IC50 value of 1.7 nM [1] [2]. | |||
T4668 | ABT-702 dihydrochloride | Adenosine Receptor | |
ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor. | |||
T6745 | 5-Iodotubercidin | 5-ITu,NSC 113939 | Adenosine Receptor |
5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibits nucleoside transporter, CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC. | |||
T21017 | 5'-Amino-5'-deoxyadenosine | 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo | Apoptosis , Adenosine Receptor |
5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ... | |||
T2615 | Flavopiridol hydrochloride | Alvocidib Hydrochloride,NSC 649890,MDL 107826A,HL 275,FLAVOPIRIDOL HCL,NSC 649890 HCl | HIV Protease , CDK , Autophagy |
Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of ... | |||
T21018 | Anisodine hydrobromide | Others | |
Anisodine hydrobromide is an inhibitor of adenosine kinase. | |||
T70617 | GP-1-515 | Others | |
GP-1-515 is an adenosine kinase inhibitor with anti-inflammatory effects. | |||
T38346 | ABT 702 hydrochloride | Others | |
Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in a... | |||
T35574 | Adenosine 5'-phosphosulfate (sodium salt) | Others | |
Adenosine 5'-phosphosulfate is an ATP and sulfate competitive inhibitor of ATP sulfurylase in humans, S. cerevisiae, and P. chrysogenum (Ki = 18, 2500, and 1500 nM, respectively). Adenosine 5'-phosphosulfate also inhibit... | |||
T26475 | A-286501 | Others | |
A-286501 is an orally active adenosine kinase inhibitor (IC50=0.47 nM). A-286501 effectively attenuates nociception by a non-opioid, non-non-steroidal anti-inflammatory drug ADO, receptor mediated mechanism. | |||
T62227 | GP3269 | Others | |
GP3269 is a selective, potent, orally active human adenosine kinase (AK) inhibitor (IC50: 11 nM) with anticonvulsant effects in rats. | |||
T83806 | Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium | Sp-ADP-α-S | Others |
Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S), an isomer of the sulfur-containing nucleotide derivative ADP-α-S, functions as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 µM. This co... | |||
T83805 | Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium | Rp-ADP-α-S | Others |
Rp-Adenosine-5'-O-(1-thiodiphosphate) (Rp-ADP-α-S), a sulfur-containing isomer of the nucleotide derivative ADP-α-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 µM. This compound... | |||
T68581 | AP23464 | Others | |
AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases, displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells (IC(50) = 14 nM. AP23464 ab... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T17143 | Toyocamycin | Vengicide | Apoptosis , Others , IRE1 , Antibiotic , Antifungal |
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. |