Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 9,000 | |||
10 mg | 在庫あり | ¥ 13,500 | |||
25 mg | 在庫あり | ¥ 26,500 | |||
50 mg | 在庫あり | ¥ 49,000 | |||
100 mg | 在庫あり | ¥ 85,500 | |||
500 mg | 在庫あり | ¥ 199,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
説明 | Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. |
ターゲット&IC50 | XBP1:80 nM |
別名 | Vengicide |
分子量 | 291.26 |
分子式 | C12H13N5O4 |
CAS No. | 606-58-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (343.34 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Toyocamycin 606-58-6 Apoptosis Cell Cycle/Checkpoint Microbiology/Virology Others IRE1 Antibiotic Antifungal RNA synthesis CDK mRNA cleavage epigenetics CDK9 inhibitor Cyclin dependent kinase molecular docking reactive oxygen species CDKs RNA Pol II phosphorylation Vengicide Inositol requiring enzyme 1 Fungal Inhibitor adenosine analog drug screening ribosome function inhibit extracellular signal-regulated kinases cancer inhibitor