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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T71534L | CIA-1 (Free base) | CIA-1(Free base) | Gamma-secretase |
CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenogr... | |||
T71534 | CIA-1 hcl(452087-38-6 Free base) | Gamma-secretase | |
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII a... | |||
T2057 | BVT 2733 | Dehydrogenase | |
BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1. | |||
T4195 | Betahistine | PT 9 base,Vasomotal,Serc base | Histamine Receptor |
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... | |||
T72006 | DCAI Hydrochloride | ||
DCAI hydrochloride is an inhibitor of nucleotide exchange and nucleotide release, by binding to the pocket adjacent to the Ras-SOS interface. | |||
T0246 | Betahistine dihydrochloride | PT-9,Betahistine 2HCl | Histamine Receptor |
Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. | |||
T2125 | Trametinib | GSK1120212,JTP-74057 | Apoptosis , MEK , Autophagy |
Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis. | |||
T5857 | Trametinib (DMSO solvate) | Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate) | Apoptosis , MEK |
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM) | |||
T17870 | cIAP1 ligand 1 | E3 ligase Ligand 12 | Others |
cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands ... | |||
T68043 | Ciamexon | Ciamexone,BM 41332,BM41332,BM-41332 | Others |
Ciamexon (Ciamexone) is a novel immunomodulator that has shown promising results in experimental models of autoimmune disease with little demonstrated cytotoxicity.Ciamexon can be used to study endocrine ophthalmopathies... | |||
T21649L | GnRH Associated Peptide (GAP) (1-13), human Acetate | GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base) | Others |
GnRH Associated Peptide (GAP) (1-13), human Acetate was found to be a potent inhibitor of prolactin secretion and to stimulate the release of gonadotropins. Active immunization with peptides corresponding to GAP sequence... | |||
T124855 | Lucialdehyde A | ||
Lucialdehyde A is a useful organic compound for research related to life sciences and the catalog number is T124855. | |||
T30929 | Cianopramine hydrochloride | Cianopramine HCl,Ro 112465 hydrochloride,Ro-11-2465 hydrochloride | |
Cianopramine hydrochloride is a bio-active chemical. | |||
T17885 | cIAP1 Ligand-Linker Conjugates 11 | E3 ligase Ligand-Linker Conjugates 33 | Others |
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in ... | |||
T17869 | cIAP1 ligand 2 | E3 ligase Ligand 11 | Others |
cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER. | |||
T10496 | Bencianol | ZY15051 | Others |
Bencianol is a semisynthetic flavonoid with anti-spasmogenic activities. | |||
T17889 | cIAP1 Ligand-Linker Conjugates 14 | E3 ligase Ligand-Linker Conjugates 36 | Others |
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1]... | |||
T25248 | Cianopramine | Ro 112465,Ro-112465,Ro112465 | |
Cianopramine is a tricyclic antidepressant and a potent neuronal serotonin (5-HT) uptake inhibitor in animals. | |||
T39103 | Pafolacianine | OTL 38 | |
Pafolacianine (OTL 38) is a near-infrared dye-based fluorescent marker utilized for identifying ovarian cancer lesions during surgeries. | |||
T76324 | GnRH Associated Peptide (1-24), human | ||
Gonadotropin-Releasing Hormone-Associated Peptide (GAP) (1-24), human, also known as hGAP-1-24, is the 1-24 fragment of the human GAP, which is connected to the luteinizing hormone-releasing hormone (LH-RH) through a 3 a... | |||
TP1420 | Microtubule-associated protein tau (26-44) | ||
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine. | |||
T76323 | GnRH Associated Peptide (25-53), human | ||
Gonadotropin-Releasing Hormone-Associated Peptide (GAP) (25-53), Human, also known as hGAP-25-53, is a fragment of the human gonadotropin-releasing hormone-associated peptide that serves as an immunogen for producing ant... | |||
T82346 | Galanin message associated peptide (1-41) amide | ||
Galanin message-associated peptide (1-41) amide is a peptide hormone [1]. | |||
T126403 | Kaempferol 3-O-vicianoside | ||
Kaempferol 3-O-vicianoside is a useful organic compound for research related to life sciences. The catalog number is T126403 and the CAS number is 110352-79-9. | |||
T17900 | cIAP1 Ligand-Linker Conjugates 8 | E3 ligase Ligand-Linker Conjugates 46 | Others |
cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1]. | |||
T29390 | M-Ciaamp | 3-Carboxyphenyl((N-((4-iodophenyl)acetyl)amino)methyl)phosphonate | |
3-Carboxyphenyl((N-((4-iodophenyl)acetyl)amino)methyl)phosphonate is a bioactive chemical. | |||
T17896 | cIAP1 Ligand-Linker Conjugates 4 | E3 ligase Ligand-Linker Conjugates 42 | Others |
cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potenti... | |||
T39609 | cIAP1 Ligand-Linker Conjugates 16 | cIAP1 Ligand-Linker Conjugates 16 | |
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs. | |||
T17888 | cIAP1 Ligand-Linker Conjugates 6 hydrochloride | E3 ligase Ligand-Linker Conjugates 35 hydrochloride | Others |
cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1]. | |||
T17901 | cIAP1 Ligand-Linker Conjugates 10 | E3 ligase Ligand-Linker Conjugates 47 | Others |
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROT... | |||
T17887 | cIAP1 Ligand-Linker Conjugates 15 | E3 ligase Ligand-Linker Conjugates 34 | Others |
cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1... | |||
T17894 | cIAP1 Ligand-Linker Conjugates 3 | E3 ligase Ligand-Linker Conjugates 40 | Others |
cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find ... | |||
T17893 | cIAP1 Ligand-Linker Conjugates 5 | E3 ligase Ligand-Linker Conjugates 39 | Others |
cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for... | |||
T80919 | Tumour-associated MUC1 epitope | ||
Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers o... | |||
T29840 | Alcian blue | ||
Alcian blue is a copper-containing dye used as a gelling agent for lubricants, for staining of bacteria and for the dyeing of histiocytes and fibroblasts in vivo. | |||
T82975 | Aranciamycin | ||
Aranciamycin (Compound 1), an anthracycline antibiotic, exhibits collagenase inhibitory activity (IC50 3.7*10^-7 M) and can inhibit DNA synthesis in tumor cells [1]. | |||
T17890 | cIAP1 Ligand-Linker Conjugates 2 Hydrochloride | E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base) | Others |
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1]. | |||
T17891 | cIAP1 Ligand-Linker Conjugates 2 | E3 ligase Ligand-Linker Conjugates 37 | Others |
cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1]. | |||
T40861 | Nerindocianine | ||
Nerindocianine is a hydrophilic, fluorescent diagnostic contrast agent that is predominantly metabolized by the kidneys, enabling non-invasive, intraoperative ureteral imaging. | |||
T17884 | cIAP1 Ligand-Linker Conjugates 11 Hydrochloride | E3 ligase Ligand-Linker Conjugates 33 Hydrochloride | Others |
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs,... | |||
T33889 | Passitrifasciatin | ||
Passitrifasciatin is a cyclopentanoid cyanohydrin glycoside isolated from Passiflora trifasciata. | |||
T29841 | Alcian yellow | C.I. Ingrain Yellow 1 | |
Alcian yellow is a biomarker. | |||
T17899 | cIAP1 Ligand-Linker Conjugates 9 | E3 ligase Ligand-Linker Conjugates 45 | Others |
cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1]. | |||
T17886 | cIAP1 Ligand-Linker Conjugates 15 hydrochloride | E3 ligase Ligand-Linker Conjugates 34 hydrochloride | Others |
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1]. | |||
T64302 | XIAP/cIAP1 antagonist-1 | ||
XIAP/cIAP1 antagonist-1 is a potent, orally active XIAP/cIAP1 antagonist that acts on XIAP (EC50: 5.1 nM) and cIAP1 (EC50: 0.32 nM). xIAP/cIAP1 antagonist-1 dose-dependently inhibits tumour growth in vivo. | |||
T79637 | CIAC001 | ||
CIAC001, a pyruvate kinase PKM2 inhibitor, exhibits anti-neuroinflammatory properties. It effectively suppresses LPS-induced production of proinflammatory nitric oxide (NO) and provides protection to immunologically acti... | |||
T17895 | cIAP1 Ligand-Linker Conjugates 1 | E3 ligase Ligand-Linker Conjugates 41 | Others |
cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1]. | |||
T25247 | Cianergoline | Cianergolinum | |
Cianergoline is a dopaminergic agonist. | |||
T17897 | cIAP1 Ligand-Linker Conjugates 13 | E3 ligase Ligand-Linker Conjugates 43 | Others |
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1]. | |||
T17892 | cIAP1 Ligand-Linker Conjugates 12 | E3 ligase Ligand-Linker Conjugates 38 | Others |
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creatin... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T5S2129 | Sciadopitysin | TNF , NF-κB | |
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o... | |||
T39435 | Myrciacetin | ||
Myrciacetin, a flavonoid derived from Rhododendron dauricum, exhibits inhibitory activity against rat lens aldose reductase, as demonstrated by an IC50 value of 13 μM. | |||
TN4196 | Helicianeoide B | Others | |
Helicianeoide B is a natural product for research related to life sciences. The catalog number is TN4196 and the CAS number is 496066-89-8. | |||
TN4455 | Lucialdehyde B | Integrase , HSV | |
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines. | |||
TN5364 | Boscialin | ||
Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM. | |||
TN2700 | 2,3-dihydrosciadopitysin | Others | |
2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard. | |||
TN4195 | Helicianeoide A | Others | |
Helicianeoide A is a natural product for research related to life sciences. The catalog number is TN4195 and the CAS number is 496066-82-1. | |||
TN6102 | Pistaciamide | ||
Pistaciamide is a natural product for research related to life sciences. The catalog number is TN6102 and the CAS number is 1029004-83-8. | |||
TN4598 | Myrciaphenone A | Others | |
Myrciaphenone A is a natural product from Limoniastrum feei (Girard) Batt. | |||
T3662 | Eleutheroside E | NF-κB | |
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03341 | ASF1B Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the ... | |||
TMPJ-01399 | ASF1A Protein, Human, Recombinant (His, T7) | Human | E. coli |
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chrom... | |||
TMPH-00043 | Fanconi-associated nuclease 1 Protein, Ailuropoda melanoleuca, Recombinant (His & Myc) | Ailuropoda melanoleuca | E. coli |
Fanconi-associated nuclease 1 Protein, Ailuropoda melanoleuca, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.5 kDa and the accession n... | |||
TMPH-03706 | LEB6 Protein, Vicia faba, Recombinant (His) | Vicia faba | P. pastoris (Yeast) |
This protein found in the seeds of many leguminous and non-leguminous plants is the source of sulfur-containing amino acids in seed meals. LEB6 Protein, Vicia faba, Recombinant (His) is expressed in yeast with N-6xHis ta... | |||
TMPH-03035 | M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) | Myrmecia pilosula | Baculovirus Insect Cells |
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum ... | |||
TMPH-03513 | Plastocyanin Protein, Spinacia oleracea, Recombinant (His & SUMO) | Spinacia oleracea | E. coli |
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I. Plastocyanin Protein, Spinacia oleracea, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SU... | |||
TMPH-00028 | Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) | AAV-2 | E. coli |
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a... | |||
TMPH-00455 | OBP28 Protein, Culex quinquefasciatus, Recombinant (His) | Culex quinquefasciatus | P. pastoris (Yeast) |
N/A. OBP28 Protein, Culex quinquefasciatus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is B0XC79. | |||
TMPY-01176 | cIAP1 Protein, Human, Recombinant (Avi) | Human | E. coli |
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r... | |||
TMPH-00296 | Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc) | Bovine | E. coli |
Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession number is P84... | |||
TMPH-00454 | OBP28 Protein, Culex quinquefasciatus, Recombinant (His & Myc) | Culex quinquefasciatus | E. coli |
N/A. OBP28 Protein, Culex quinquefasciatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22 kDa and the accession number is B0XC79. | |||
TMPJ-00353 | ILDR2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homo... |